Protein Alignment Hsc70-1 and hsp70

DIOPT Version :9

• Sequence 1: NP_524063.1
• Gene: Hsc70-1 / 39542
• FlyBaseID: FBgn0001216
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_001106370.1
• Gene: hsp70 / 100037899
• XenbaseID: XB-GENE-485626
• Length: 643
• Species: Xenopus tropicalis
• Alignment Length: 640
• Identity: 503/640 - (78%)
• Similarity: 576/640 - (90%)
• Gaps: 7/640 - (1%)

  Fly     6 AVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTESERLIGDAAKNQVAMNPNNTIFDA 70
            ||||||||||||||||||||||||||||||||||||||||::||||||||||||||||.||:|||
 Frog     7 AVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPQNTVFDA 71

  Fly    71 KRLIGRRFDDATVQSDMKHWPFEVFAENGKPRIRVEYKGERKSFYPEEVSSMVLTKMRETAEAYL 135
            ||||||:|:|..||||:|||||:|.:::|||:::||:|||.|:|:|||:|||||.||:|||||||
 Frog    72 KRLIGRKFNDPVVQSDLKHWPFQVVSDHGKPKVKVEFKGEEKTFFPEEISSMVLIKMKETAEAYL 136

  Fly   136 GGTVTDAVVTVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGLDKQGTSERNVLIFDL 200
            |..||:||:||||||||||||||||||.||||||||||||||||||||||||....|||||||||
 Frog   137 GHAVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDKGTRGERNVLIFDL 201

  Fly   201 GGGTFDVSVLTIEDGIFEVKATAGDTHLGGEDFDNRLVNHFVQEFQRKHKKDLGQNKRALRRLRT 265
            ||||||||:|||:|||||||||||||||||||||||:||||::||:||||||:.|||||||||||
 Frog   202 GGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRMVNHFMEEFKRKHKKDISQNKRALRRLRT 266

  Fly   266 ACERAKRTLSSSTQASIEIDSLFEGVDFYTSVTRARFEELNGDLFRGTMEPVAKALRDAKMDKGQ 330
            ||||||||||||:||||||||||||:|||||:||||||||..||||||:|||.|||||||:||.|
 Frog   267 ACERAKRTLSSSSQASIEIDSLFEGIDFYTSITRARFEELCSDLFRGTLEPVEKALRDAKLDKSQ 331

  Fly   331 IHDIVLVGGSTRIPKVQRLLQDFFNGKELNKSINPDEAVAYGAAVQAAILHGDKSEAVQDLLLLD 395
            |.:||||||||||||||:||||||||:|||||||||||||||||||||||.|||||.||||||||
 Frog   332 IDEIVLVGGSTRIPKVQKLLQDFFNGRELNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLD 396

  Fly   396 VTPLSLGIETAGGVMTTLIKRNTTIPTKQTQIFTTYADNQPGVLIQVFEGERAMTRDNNSLGKFE 460
            |.|||||:||||||||.||||||||||||||.||||:||||||||||||||||||:|||.|||||
 Frog   397 VAPLSLGLETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVFEGERAMTKDNNLLGKFE 461

  Fly   461 LSAIPPAPRGVPQVEVTFDIDANGILNVTALEKSTGKENRITITNDKGRLSKEDIERMVNDAEAY 525
            ||.||||||||||:||||||||||||||:|:|||:||:|:||||||||||||||||:||.:||.|
 Frog   462 LSGIPPAPRGVPQIEVTFDIDANGILNVSAVEKSSGKQNKITITNDKGRLSKEDIEKMVQEAERY 526

  Fly   526 RQADEQQRDRINAKNQLESYCFQLRSTLDDEHLSSRFSPADRETIQQRSSETIAWLDANQLAERQ 590
            :..|:.||::|:|||.||||.|.|:|.::||::..:.|..|:..|.::.::.|:||:.|||||:.
 Frog   527 KADDDAQREKIDAKNSLESYAFNLKSMVEDENMKGKISEGDKRIISEKCTQIISWLENNQLAEKD 591

  Fly   591 EFEHKQQELERICSPIITRLYQGAGMAPPPTAGGSNPGAT----GGSGPTIEEVD 641
            |:..:|:||||:|.||||:||||   :.|.:..||:.||.    |.|||||||||
 Frog   592 EYAFQQKELERVCQPIITKLYQG---SMPGSMPGSSCGAQARQGGSSGPTIEEVD 643

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-1	NP_524063.1	PTZ00009	1..641	CDD:240227	501/638 (79%)
		HSPA1-2_6-8-like_NBD	6..381	CDD:212675	320/374 (86%)
hsp70	NP_001106370.1	PTZ00009	2..643	CDD:240227	501/638 (79%)
		HSPA1-2_6-8-like_NBD	7..382	CDD:212675	320/374 (86%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D180577at33208
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	1	1.000	-	-		otm47512
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X148
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.010