DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment ssp2 and NXF2

DIOPT Version :9

Sequence 1:NP_001287065.1 Gene:ssp2 / 39540 FlyBaseID:FBgn0036389 Length:982 Species:Drosophila melanogaster
Sequence 2:NP_071336.1 Gene:NXF2 / 56001 HGNCID:8072 Length:626 Species:Homo sapiens


Alignment Length:335 Identity:73/335 - (21%)
Similarity:135/335 - (40%) Gaps:74/335 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly     9 ALKDDSYIFLADKTHDDVSNILQQWKTNNQPPLQQLHLQYNNEAFKNNSK-------TFTRPKR- 65
            ||||.||     |.:||.:..:..:..::..|.          :.||..|       ..|..|| 
Human   176 ALKDVSY-----KIYDDENQKICIFVNHSTAPY----------SVKNKLKPGQMEMLKLTMNKRY 225

  Fly    66 ---------RNLDFSQNGAGNDSGV---GTGSVAGAPAMLQLEIGGLVTTNM--HKSF----LQD 112
                     :||.|..:..|.|..:   ....:|....:::.....|::.|:  :|.:    |.|
Human   226 NVSQQALDLQNLRFDPDLMGRDIDIILNRRNCMAATLKIIERNFPELLSLNLCNNKLYQLDGLSD 290

  Fly   113 TSPPSSICSSMNTERMNNSLITSADFTNLNFLQ-STIGLEQDPNLTTTLTNQTTDNMGIGG---- 172
            .:..:....::|..:  |.|.::.:...:..|: ..:.||.:| |.:|.::|:.....|..    
Human   291 ITEKAPKVKTLNLSK--NKLESAWELGKVKGLKLEELWLEGNP-LCSTFSDQSAYVSAIRDCFPK 352

  Fly   173 --SIGGYTLS-DMIRDRKALESLTMCEDDGT---LIKDSHIGQIDE-ISLTLSKTASGC--STMD 228
              .:.|..|| .:|.|..:.|::..|:::.|   .:|...:..:.: .|:..|....|.  :..|
Human   353 LLRLDGRELSAPVIVDIDSSETMKPCKENFTGSETLKHLVLQFLQQYYSIYDSGDRQGLLGAYHD 417

  Fly   229 NSTDSMSIPLAADRTMPVVVSAVCPALQ--RTM------ILGEEMIGDTTFNLVDSLTTSAL--- 282
            .:..|::||.....:.|   |::|...:  |.|      .|..|::..|..::||||  |||   
Human   418 EACFSLAIPFDPKDSAP---SSLCKYFEDSRNMKTLKDPYLKGELLRRTKRDIVDSL--SALPKT 477

  Fly   283 QSESESLPVD 292
            |.:..|:.||
Human   478 QHDLSSILVD 487

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ssp2NP_001287065.1 PHA03247 <676..965 CDD:223021
NXF2NP_071336.1 Tap-RNA_bind 121..203 CDD:312616 9/31 (29%)
leucine-rich repeat 229..271 CDD:275382 6/41 (15%)
LRR_8 270..332 CDD:316378 12/64 (19%)
LRR 1 271..296 5/24 (21%)
leucine-rich repeat 272..297 CDD:275382 5/24 (21%)
LRR 2 297..320 3/24 (13%)
leucine-rich repeat 298..321 CDD:275382 3/24 (13%)
LRR 3 321..348 7/27 (26%)
leucine-rich repeat 322..352 CDD:275382 7/30 (23%)
LRR 4 349..376 6/26 (23%)
NTF2_like 391..543 CDD:324324 26/102 (25%)
TAP_C 570..623 CDD:197882
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3763
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.