DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ssp2 and Nxf7

DIOPT Version :9

Sequence 1:	NP_001287065.1	Gene:	ssp2 / 39540	FlyBaseID:	FBgn0036389	Length:	982	Species:	Drosophila melanogaster
Sequence 2:	NP_001032293.1	Gene:	Nxf7 / 501621	RGDID:	1566170	Length:	614	Species:	Rattus norvegicus

Alignment Length:	280	Identity:	47/280 - (16%)
Similarity:	94/280 - (33%)	Gaps:	86/280 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   253 PALQRTMILG------EEMIGDTTFNLVDSLTTSALQSESESLPVDG--NATFKRPTASATTADE 309
            |:::.|...|      ||.:.| ..::.......|.:.|.|....||  .:.||.........|:
  Rat    62 PSVRHTPYSGRRKSREEEHVED-QIHITVWRDEKAQKREVEQFTEDGTLESWFKVTIPCGRKCDK 125

  Fly   310 TQVLTGRQMNTTFTDGCNTPEGRCETP-----ENIDR-KLALLTMESSTPLTTNMRSHCYHNNNN 368
            ||::             |:....|..|     .:.|: ::.....:||  :...::...|..::.
  Rat   126 TQLM-------------NSVHSLCSVPFTPVDFHCDKYRIQFFVQDSS--IAYALKDVSYKISSE 175

  Fly   369 NNKAGYTPTLKGRGDMNLSPIVGATPQKPTGTAPGRLNNTFEPVAKTAPFNGEKFVLDTMELLEQ 433
                          |....||. ..|    ..||..:.|.|                 |.|.:||
  Rat   176 --------------DFEKIPIF-VNP----SVAPYSVQNRF-----------------TREQMEQ 204

  Fly   434 IEQPLDGTYNLQMSEQH----RQMQCVMDLAEAEVEMLAQQGD---------EEQFENMLAELGK 485
            ::..:...|::   .||    ::::...||....::|:..:..         :|.|..:|:
  Rat   205 LKLAMKKRYDI---SQHALCLKKLRFDPDLMNHNIDMILNRRSCMTATLQIIQEDFPKLLS---- 262

  Fly   486 VNTLNEEQLKMQKSLDTIKR 505
            :|..:.:..::....|.:|:
  Rat   263 LNLSSNKLFQLDSLFDVVKK 282

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ssp2	NP_001287065.1	PHA03247	<676..965	CDD:223021
Nxf7	NP_001032293.1	Tap-RNA_bind	110..191	CDD:401194	17/114 (15%)
		leucine-rich repeat	217..259	CDD:275382	7/41 (17%)
		LRR_8	258..320	CDD:404697	4/29 (14%)
		leucine-rich repeat	260..285	CDD:275382	4/27 (15%)
		leucine-rich repeat	286..309	CDD:275382
		leucine-rich repeat	310..340	CDD:275382
		NTF2_like	380..531	CDD:415585
		TAP_C	549..611	CDD:197882
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3763
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900