DRSC/TRiP Functional Genomics Resources

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Protein Alignment Meics and zgc:113135

DIOPT Version :9

Sequence 1:NP_524062.1 Gene:Meics / 39539 FlyBaseID:FBgn0025874 Length:583 Species:Drosophila melanogaster
Sequence 2:NP_001013324.1 Gene:zgc:113135 / 503712 ZFINID:ZDB-GENE-050306-7 Length:323 Species:Danio rerio


Alignment Length:299 Identity:108/299 - (36%)
Similarity:147/299 - (49%) Gaps:41/299 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly   288 TTHRRRHTGERP---FKCPLCPKAYTHGPTLKSHMHTHDEEKGHKCPQCDKTFYTRGNLRAHIQR 349
            |:.|||....:.   |.|....|:::..|.|    ..|..||.:.|.||:|:||..|||:.|::.
Zfish    62 TSSRRRPRKSKSSCNFSCKQSRKSFSQKPNL----DVHTREKPYTCKQCEKSFYNTGNLKVHMRI 122

  Fly   350 HTGERPYKCPDCPQTFAKNSGLKLHSRLHKEERPFKCELCGKGFVQNQHLITHLRVHNGDRQFKC 414
            |||||||.|..|.::|.....|.:|.|:|..||.:.|..|||...||.:|..|:|.|.|:|.|.|
Zfish   123 HTGERPYTCQQCGKSFYSTGNLAVHRRIHTGERLYFCPQCGKSCKQNGNLEAHMRTHTGERSFIC 187

  Fly   415 PDCDKSFFEKSNMMKHQRTHSGIKPFKCEECGQAFSHNHHLKSHLRIHTGEKPYKCDQCGKGFSA 479
            ..|.|.|.:|.|:..|.|.|:|.||:.|.|||::|.|...||.|:..|||:||:.|..|||.|:.
Zfish   188 TQCGKGFSQKQNLTIHMRIHTGEKPYTCTECGKSFPHAGSLKHHMISHTGQKPFACAHCGKSFTT 252

  Fly   480 NQSLMKHTLWHVDNNDRPFKCSQCPKAYDTQQSLRGHEKTHKNPDEPKTLHQCPHCDVRFALKKT 544
            ..|||.|...|....  .|.|.||.|:...:.|::.|.|.|...              ||.    
Zfish   253 KASLMNHMNGHTGTT--VFTCDQCGKSLTCKDSIKQHMKIHSGE--------------RFR---- 297

  Fly   545 LDKHITSHKIRPHPCPQCPEGFFSQKSLKKHLRLHNLKK 583
                          |.:|.:.|..::||..|.:|||.:|
Zfish   298 --------------CSECRKVFKHKRSLVNHTKLHNGEK 322

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
MeicsNP_524062.1 zf-AD 21..95 CDD:285071
C2H2 Zn finger 242..262 CDD:275368
C2H2 Zn finger 274..294 CDD:275368 3/5 (60%)
zf-H2C2_2 287..311 CDD:290200 7/25 (28%)
C2H2 Zn finger 302..322 CDD:275368 4/19 (21%)
C2H2 Zn finger 330..350 CDD:275368 10/19 (53%)
zf-H2C2_2 342..366 CDD:290200 12/23 (52%)
C2H2 Zn finger 358..378 CDD:275368 6/19 (32%)
C2H2 Zn finger 386..406 CDD:275368 9/19 (47%)
COG5048 <395..583 CDD:227381 65/187 (35%)
zf-C2H2 412..434 CDD:278523 9/21 (43%)
C2H2 Zn finger 414..434 CDD:275368 8/19 (42%)
zf-H2C2_2 426..451 CDD:290200 12/24 (50%)
C2H2 Zn finger 442..462 CDD:275368 9/19 (47%)
zf-H2C2_2 454..478 CDD:290200 12/23 (52%)
C2H2 Zn finger 470..486 CDD:275368 8/15 (53%)
C2H2 Zn finger 500..520 CDD:275368 7/19 (37%)
C2H2 Zn finger 532..552 CDD:275370 2/19 (11%)
C2H2 Zn finger 559..579 CDD:275370 6/19 (32%)
zgc:113135NP_001013324.1 C2H2 Zn finger 79..95 CDD:275368 4/19 (21%)
C2H2 Zn finger 103..123 CDD:275368 10/19 (53%)
zf-H2C2_2 115..138 CDD:290200 12/22 (55%)
C2H2 Zn finger 131..151 CDD:275368 6/19 (32%)
COG5048 <159..316 CDD:227381 66/190 (35%)
C2H2 Zn finger 159..179 CDD:275368 9/19 (47%)
zf-H2C2_2 171..196 CDD:290200 11/24 (46%)
C2H2 Zn finger 187..207 CDD:275368 8/19 (42%)
zf-H2C2_2 199..222 CDD:290200 11/22 (50%)
C2H2 Zn finger 215..235 CDD:275368 9/19 (47%)
zf-H2C2_2 227..252 CDD:290200 13/24 (54%)
C2H2 Zn finger 243..263 CDD:275368 9/19 (47%)
C2H2 Zn finger 271..291 CDD:275368 7/19 (37%)
C2H2 Zn finger 298..318 CDD:275368 6/19 (32%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 1 0.900 - - OOG6_100488
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.900

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