Protein Alignment Meics and CG3281

DIOPT Version :10

• Sequence 1: NP_524062.1
• Gene: Meics / 39539
• FlyBaseID: FBgn0025874
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_650132.1
• Gene: CG3281 / 41445
• FlyBaseID: FBgn0260741
• Length: 538
• Species: Drosophila melanogaster
• Alignment Length: 614
• Identity: 141/614 - (22%)
• Similarity: 223/614 - (36%)
• Gaps: 151/614 - (24%)

  Fly    19 KNCRACAE--------HSSILVDLFSKEISDPPIWEMLNSILPEICRVKRDEMPQKICPTCLVAA 75
            :.||.|.|        |..|..:....|     :|::|.::...........:|..:|..|....
  Fly    13 QTCRVCLETHETNLYVHDEIKYNDLKLE-----LWQLLEAVSKLKWTWTDPNLPMHLCQNCARRL 72

  Fly    76 QNAFHFRHKCEQSFQFFSQLLQLDKSNSNLSRSHCRRGTMNPLIPFEIVGCEDPLDTNVTKLDAN 140
            ..|:.|..:.|.:.:....|.:..                      |:....|.:..:|.:|
  Fly    73 IGAYEFIVEVENAHETLQNLFEQQ----------------------EVAAKPDEVHVDVVEL--- 112

  Fly   141 RPDVKTDIDEPTDGKATNGQESEPLQEVFEITMNDIKTEDEVSIQETFED----AFDEE------ 195
                   ||:  |...:..|.   |...|        .|..|.::|.:.|    ||..:
  Fly   113 -------IDQ--DDVVSMAQY---LSTSF--------AEQHVEMEEKYGDQDCSAFTSDVGEEPL 157

  Fly   196 NDNNNTDSEREDSDQWTVGSTE-DQDEPWIPGGGGRQTVGGNNQSLLCTECGVSYSTQKALARHV 259
            ..:.:.|.|.|||.|......| :..|...|...|.:.....|....|..|...::..::|.||.
  Fly   158 YASEDRDDEPEDSFQLKPRPDEIENRELSRPSQLGSRLNHSANFIYKCAVCPRVFAKSESLTRHF 222

  Fly   260 AK-HKEQGDTQKPHLC-DFCGRGFRTNAQLTTHRRRHTGERPFKCPLCPKAYTHGPTLKSHM--- 319
            :: ||...|.....|. :.||.|..|                  |..||:.:....||:.||
  Fly   223 SQAHKLTADVAAMKLANESCGTGLLT------------------CEHCPRTFKRQDTLRRHMQAF 269

  Fly   320 ----------HTHDEE------KGHKCPQCDKTFYTRGNLRAHIQRHTGERPYKCPDCPQTFAKN 368
                      .|.|..      |...||.|..:|.. .:|..||:||||:.||||..|.:.|.::
  Fly   270 HPDAIALEPEETTDNSARKRIAKRRDCPHCGLSFPV-SSLTIHIRRHTGDNPYKCDQCEKAFPRS 333

  Fly   369 SGLKLHSRLHKEERPFKCELCGKGFVQNQHLITHLRVHNGDRQFKCPDCDKSFFEKSNMMKHQRT 433
            ..|.||.|.|..|||.:|::|.|.|:....|..|:|:|.|.|.:.|..|.|||.:.:::..|.|.
  Fly   334 QDLSLHMRQHTGERPSECKICSKKFISQNKLARHMRLHTGQRPYSCKMCSKSFVQSNDLKIHMRR 398

  Fly   434 HSGIKPFKCEECGQAFSHNHHLKSHLRIHTGEKPYKC-----DQCGKGFSA------------NQ 481
            |:|.:|::|..||::|.    ..|||.||...|.:..     ::....|:|            ::
  Fly   399 HTGERPYQCGVCGESFV----CGSHLNIHRNRKGHLIAVIPGNEVEANFAADPYVNARVNQRRSE 459

  Fly   482 SLMKHTLWHVDNNDRPFKCSQCPKAYDTQQSLRGHEKTHKNPDEPKTLHQCPHCDVRFALKKTLD 546
            .:.:..|..:..|....:....||                 ||.|...::|..|:.:|.....|.
  Fly   460 DIERMRLQRIPENQLQQRLENLPK-----------------PDVPAMCYKCGVCEQKFKSGALLT 507

  Fly   547 KHITSHKIRPHPCPQCPEGFF--SQKSLK 573
            .|  .:|:..:...:..|..|  :||.:|
  Fly   508 VH--RNKMSHYEIERVYENPFGKNQKIIK 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Meics	NP_524062.1	zf-AD	20..95	CDD:462262	15/82 (18%)
		C2H2 Zn finger	242..262	CDD:275368	5/20 (25%)
		C2H2 Zn finger	274..294	CDD:275368	4/20 (20%)
		SFP1	<296..374	CDD:227516	28/96 (29%)
		COG5048	<299..486	CDD:227381	67/222 (30%)
		C2H2 Zn finger	302..322	CDD:275368	7/32 (22%)
		C2H2 Zn finger	330..350	CDD:275368	7/19 (37%)
		C2H2 Zn finger	358..378	CDD:275368	7/19 (37%)
		C2H2 Zn finger	386..406	CDD:275368	7/19 (37%)
		COG5048	<395..583	CDD:227381	46/198 (23%)
		C2H2 Zn finger	414..434	CDD:275368	7/19 (37%)
		C2H2 Zn finger	442..462	CDD:275368	7/19 (37%)
		C2H2 Zn finger	470..486	CDD:275368	2/32 (6%)
		C2H2 Zn finger	500..520	CDD:275368	2/19 (11%)
		C2H2 Zn finger	532..552	CDD:275370	5/19 (26%)
		C2H2 Zn finger	559..579	CDD:275370	5/17 (29%)
CG3281	NP_650132.1	zf-AD	15..91	CDD:214871	15/80 (19%)
		C2H2 Zn finger	205..226	CDD:275368	5/20 (25%)
		C2H2 Zn finger	249..266	CDD:275368	5/16 (31%)
		COG5048	<294..>391	CDD:227381	40/97 (41%)
		C2H2 Zn finger	296..315	CDD:275368	7/19 (37%)
		C2H2 Zn finger	323..343	CDD:275368	7/19 (37%)
		C2H2 Zn finger	351..371	CDD:275368	7/19 (37%)
		zf-H2C2_2	364..388	CDD:463886	11/23 (48%)
		C2H2 Zn finger	379..399	CDD:275368	7/19 (37%)
		zf-H2C2_2	391..416	CDD:463886	9/28 (32%)
		C2H2 Zn finger	407..424	CDD:275368	8/20 (40%)