Protein Alignment Meics and CG15269

DIOPT Version :10

• Sequence 1: NP_524062.1
• Gene: Meics / 39539
• FlyBaseID: FBgn0025874
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_609739.2
• Gene: CG15269 / 34887
• FlyBaseID: FBgn0028878
• Length: 587
• Species: Drosophila melanogaster
• Alignment Length: 624
• Identity: 162/624 - (25%)
• Similarity: 240/624 - (38%)
• Gaps: 135/624 - (21%)

  Fly    12 SVDASMGKNCRACAEHSSILVDLFSKEISDPPIWEMLNSILPEICRVKRDEMPQ----------- 65
            |:...:||..::..:.|:.::|| ||..|        |||          ..||
  Fly    39 SISKILGKERKSAQDTSTNILDL-SKSSS--------NSI----------RSPQALGGLAIPSTP 84

  Fly    66 ------KICPTCLVAAQNAFHFRHKCEQSFQFFSQLL--------------------QLDKSNSN 104
                  .:.|..|||..||..|      ..|||..||                    |..:...:
  Fly    85 YASGAYSMLPPDLVAMANATKF------YAQFFPHLLPAYAAAAAAAGLSTPPTSPYQTHQHQQH 143

  Fly   105 LSRSHCR-------RGTMNPLIPFEIVGCEDPLDTNVTKLDA-NRPDVKTDIDE----PTDGKAT 157
            |.....|       .|::.|..|.:  ..:.||..  ||..| .|||....:|.    .|.|...
  Fly   144 LPNQQKRFFAPYVINGSVPPPPPLQ--QQQQPLIR--TKSTACTRPDCPECLDYYQRLQTGGYKQ 204

  Fly   158 NGQESEPLQEVFEITMNDIKTEDEVSIQETFEDAFDEENDNNNTDSEREDSDQWTVGSTEDQDEP 222
            ......|.......:...|:...::.:..|...|....:....|:..........||..     |
  Fly   205 TAPLISPAASSVSSSTGSIRPVRDLIMSATGGAASTNISLTTVTNLSLNSVQATAVGMM-----P 264

  Fly   223 WIPGGGGRQTVGGNNQSLLCTECGV-SYSTQKALARHVAKHKEQGDTQKPHLCDFCGRGFRTNAQ 286
            .:.||.....||.|:.::    .|: .|:...|             .:..:.|..|.:.|..:..
  Fly   265 KMTGGLITTAVGSNSGAI----GGIGGYNATSA-------------EEISYKCRICEKVFGCSET 312

  Fly   287 LTTHRRRHTGERPFKCPLCPKAYTHGPTLKSHMHTH--DEEKGHKCPQCDKTFYTRGNLRAHIQR 349
            |..|.:.|...| ::|..|.|.::.....|.|:..|  .:|...:||:|.|||..:|.|.:|::.
  Fly   313 LQAHEKTHKSPR-YECADCGKGFSQLRNYKYHLSVHRGTKEFAAECPECGKTFNDKGYLSSHLKI 376

  Fly   350 HTGERPYKCPDCPQTFAKNSGLKLHSRLHKEERPFKCELCGKGFVQNQHLITHLRVHNGDRQFKC 414
            |...:.|:||.||::|.:.....:|.|:|...:|.||..|||.|.:...|..|:|.|:|::.::|
  Fly   377 HRNRKEYECPYCPKSFNQRVAFNMHVRIHTGVKPHKCNECGKRFSRKMLLKQHMRTHSGEKPYQC 441

  Fly   415 PDCDKSFFEKSNMMKHQRTHSGIKPFKCEECGQAFSHNHHLKSHLRIHTGEKPYKC--DQCGKGF 477
            ..|.|||.::|||..|.|.|||||||.|..|.:||:..||||:||..|||.|||.|  ..|.:.|
  Fly   442 SVCGKSFADRSNMTLHHRLHSGIKPFSCPLCPKAFTKKHHLKTHLNYHTGCKPYVCPHPNCNQAF 506

  Fly   478 SANQSLMKHTLWHVDNNDRPFKCSQCPKAYD----TQQSLRGHEKTHKNPDEPKTLHQCPHCDVR 538
            :.:.::..|..          ||...|  .|    |..:|....|....|  |.||        .
  Fly   507 TQSSNMRTHAK----------KCQYRP--LDGLTVTSSALPVPGKQQTGP--PPTL--------A 549

  Fly   539 FALKKTLDKHITSHKIRPHPCPQCPEGFFSQKSLKKHLR 577
            .|:.:|.........:.|...|..|.   ||::|..:||
  Fly   550 MAMAQTFQMPPPPGVLTPGSGPSQPP---SQQTLLSNLR 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Meics	NP_524062.1	zf-AD	20..95	CDD:462262	21/91 (23%)
		C2H2 Zn finger	242..262	CDD:275368	3/20 (15%)
		C2H2 Zn finger	274..294	CDD:275368	5/19 (26%)
		SFP1	<296..374	CDD:227516	24/79 (30%)
		COG5048	<299..486	CDD:227381	74/190 (39%)
		C2H2 Zn finger	302..322	CDD:275368	5/19 (26%)
		C2H2 Zn finger	330..350	CDD:275368	9/19 (47%)
		C2H2 Zn finger	358..378	CDD:275368	7/19 (37%)
		C2H2 Zn finger	386..406	CDD:275368	8/19 (42%)
		COG5048	<395..583	CDD:227381	63/189 (33%)
		C2H2 Zn finger	414..434	CDD:275368	10/19 (53%)
		C2H2 Zn finger	442..462	CDD:275368	10/19 (53%)
		C2H2 Zn finger	470..486	CDD:275368	3/17 (18%)
		C2H2 Zn finger	500..520	CDD:275368	6/23 (26%)
		C2H2 Zn finger	532..552	CDD:275370	2/19 (11%)
		C2H2 Zn finger	559..579	CDD:275370	7/19 (37%)
CG15269	NP_609739.2	C2H2 Zn finger	300..320	CDD:275368	5/19 (26%)
		C2H2 Zn finger	327..347	CDD:275368	5/19 (26%)
		C2H2 Zn finger	357..377	CDD:275368	9/19 (47%)
		COG5048	<370..515	CDD:227381	60/144 (42%)
		C2H2 Zn finger	385..405	CDD:275368	7/19 (37%)
		C2H2 Zn finger	413..433	CDD:275368	8/19 (42%)
		C2H2 Zn finger	441..461	CDD:275368	10/19 (53%)
		C2H2 Zn finger	469..489	CDD:275368	10/19 (53%)
		C2H2 Zn finger	497..515	CDD:275368	3/17 (18%)