Protein Alignment Meics and Zfp286

DIOPT Version :10

• Sequence 1: NP_524062.1
• Gene: Meics / 39539
• FlyBaseID: FBgn0025874
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: XP_006532606.3
• Gene: Zfp286 / 192651
• MGIID: 2384758
• Length: 539
• Species: Mus musculus
• Alignment Length: 513
• Identity: 156/513 - (30%)
• Similarity: 233/513 - (45%)
• Gaps: 98/513 - (19%)

  Fly   103 SNLSRSHCRRGTMNPLIPFEIVGCEDPLDTNVTKLDANRPDVKTDIDEPTDGKATNGQESEPLQE 167
            |...|..|||..          ||.: ....:..|..::||         :..:.:|:|...|::
Mouse    84 SPFPREECRRRR----------GCSE-THCQIPGLPISKPD---------NYNSEDGKELSKLEK 128

  Fly   168 VFEITMNDIKTEDEVSIQETFEDAFDEENDNNNTDSEREDSDQWTVGSTEDQDEPWIPGGGGRQ- 231
            ..:.:.:|::|..| |.:.|....|.:|..|..|::...|||.    .|..:.|.|:.   .||
Mouse   129 SPKCSDSDMETRPE-SKESTSVLDFSKEESNRLTENTASDSDI----ETALECERWLE---HRQR 185

  Fly   232 -------TVGGNNQSLLCTECG------VSYSTQKALARHVAKHKEQGDT--------------- 268
                   .:..:..||...|.|      .|:|.:..|.......|...|.
Mouse   186 NRERYPRQMSAHRNSLPAQEDGERDVYWKSFSQKPLLTTDDRDPKGSWDVHTLGKRLKQKSKLMT 250

  Fly   269 -------QKPHLCDFCGRGFRTNAQLTTHRRRHTGERPFKCPLCPKAYTHGPTLKSHMHTHDEEK 326
                   :|||.||.||..|...:.|..|:|.||||:|:.|..|.|:::|...|..|..||....
Mouse   251 KQRPYKEKKPHKCDECGELFTYRSVLIRHQRVHTGEKPYTCSECGKSFSHRANLTKHQRTHTRIL 315

  Fly   327 GHKCPQCDKTFYTRGNLRAHIQRHTGERPYKCPDCPQTFAKNSGLKLHSRLHKEERPFKCELCGK 391
             .:|.:|.|||....:|..|.:.|.|||||:|.:|.:.|.:::.|..|..:|...:|::|..|.|
Mouse   316 -FECGECKKTFIESSSLEVHQRIHIGERPYECAECGKGFNRSTHLAQHQLIHTGVKPYECNECDK 379

  Fly   392 GFVQNQHLITHLRVHNGDRQFKCPDCDKSFFEKSNMMKHQRTHSGIKPFKCEECGQAFSHNHHLK 456
            .|:.:..||.|.|.|.|::.:||.||.|:|...|::.||||.|:|.:|::|.|||:.||.:.||.
Mouse   380 AFIHSSALIKHQRTHTGEKPYKCQDCGKAFSHCSSLTKHQRVHTGERPYECSECGKTFSQSTHLV 444

  Fly   457 SHLRIHTGEKPYKCDQCGKGFSANQSLMKHTLWHVDNNDRPFKCSQCPKAYDTQQSLRGHEKTHK 521
            .|.|||||||||:|::|||.||.:.:..||...|:  ..:|:||.:|.||:....:|..|::||
Mouse   445 QHQRIHTGEKPYECNECGKTFSRSSNFAKHQRIHM--GKKPYKCGECGKAFVHSSALIQHQRTH- 506

  Fly   522 NPDEPKTLHQCPHCDVRFALKKTLDKHITSHKIRPHPCPQCPEGFFSQKSLKKHLRLH 579
                                        |..|  |..|.:|.:.|.|..||.:|.|.|
Mouse   507 ----------------------------TGEK--PFRCTECGKSFKSSPSLIRHQRTH 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Meics	NP_524062.1	zf-AD	20..95	CDD:462262
		C2H2 Zn finger	242..262	CDD:275368	5/25 (20%)
		C2H2 Zn finger	274..294	CDD:275368	8/19 (42%)
		SFP1	<296..374	CDD:227516	28/77 (36%)
		COG5048	<299..486	CDD:227381	77/186 (41%)
		C2H2 Zn finger	302..322	CDD:275368	6/19 (32%)
		C2H2 Zn finger	330..350	CDD:275368	7/19 (37%)
		C2H2 Zn finger	358..378	CDD:275368	5/19 (26%)
		C2H2 Zn finger	386..406	CDD:275368	8/19 (42%)
		COG5048	<395..583	CDD:227381	69/185 (37%)
		C2H2 Zn finger	414..434	CDD:275368	10/19 (53%)
		C2H2 Zn finger	442..462	CDD:275368	10/19 (53%)
		C2H2 Zn finger	470..486	CDD:275368	6/15 (40%)
		C2H2 Zn finger	500..520	CDD:275368	6/19 (32%)
		C2H2 Zn finger	532..552	CDD:275370	1/19 (5%)
		C2H2 Zn finger	559..579	CDD:275370	8/19 (42%)
Zfp286	XP_006532606.3	C2H2 Zn finger	239..255	CDD:275368	0/15 (0%)
		C2H2 Zn finger	263..283	CDD:275368	8/19 (42%)
		zf-H2C2_2	276..300	CDD:463886	11/23 (48%)
		zf-C2H2	289..311	CDD:395048	6/21 (29%)
		C2H2 Zn finger	291..311	CDD:275368	6/19 (32%)
		C2H2 Zn finger	318..338	CDD:275368	7/19 (37%)
		zf-H2C2_2	330..355	CDD:463886	11/24 (46%)
		C2H2 Zn finger	346..366	CDD:275368	5/19 (26%)
		COG5048	<370..530	CDD:227381	71/192 (37%)
		C2H2 Zn finger	374..394	CDD:275368	8/19 (42%)
		C2H2 Zn finger	402..422	CDD:275368	10/19 (53%)
		C2H2 Zn finger	430..450	CDD:275368	10/19 (53%)
		C2H2 Zn finger	458..478	CDD:275368	8/19 (42%)
		C2H2 Zn finger	486..506	CDD:275368	6/19 (32%)
		C2H2 Zn finger	514..534	CDD:275368	8/19 (42%)