DRSC/TRiP Functional Genomics Resources

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Protein Alignment Meics and zgc:174646

DIOPT Version :9

Sequence 1:NP_524062.1 Gene:Meics / 39539 FlyBaseID:FBgn0025874 Length:583 Species:Drosophila melanogaster
Sequence 2:NP_001116087.1 Gene:zgc:174646 / 100142637 ZFINID:ZDB-GENE-080305-6 Length:408 Species:Danio rerio


Alignment Length:410 Identity:144/410 - (35%)
Similarity:217/410 - (52%) Gaps:24/410 - (5%)


- Green bases have known domain annotations that are detailed below.


  Fly   176 IKTEDE-VSIQETFEDAFDEENDNNNTDSEREDSDQWTVGSTEDQDEPWIPGGGGRQTVGG---- 235
            ||.|:| |.|:|||  ...:|:....||..::..:     |.|::....|.|....:| ||    
Zfish     4 IKEENEDVKIEETF--TVKQEDLQEQTDLIKDYEE-----SKEEEHRVKIEGKTHLET-GGILKT 60

  Fly   236 -NNQSLLCTECGVSYSTQKALARHVAKHKEQGDTQKPHLCDFCGRGFRTNAQLTTHRRRHTGERP 299
             :.....||:||.|.:.:..|..|:..|    ..:||..|..||:.|..:|.|..|...|||.:|
Zfish    61 RDKSCFTCTQCGKSLANKSKLKIHMKIH----TGEKPFTCTQCGKSFSHSANLNQHMMIHTGGKP 121

  Fly   300 FKCPLCPKAYTHGPTLKSHMHTHDEEKGHKCPQCDKTFYTRGNLRAHIQRHTGERPYKCPDCPQT 364
            |.|..|.|:::...||..||..|..|:...|.||.|:|....||..|::.||||:|:.|..|.:.
Zfish   122 FTCHQCGKSFSKPSTLYRHMRIHTGEQPFTCTQCGKSFNQPSNLNLHMRIHTGEKPFTCTQCGKN 186

  Fly   365 FAKNSGLKLHSRLHKEERPFKCELCGKGFVQNQHLITHLRVHNGDRQFKCPDCDKSFFEKSNMMK 429
            |..:|.|..|..:|..|:||.|..||:.|..:..|..|:|:|.|::.|.|..|.|||.:.:::.:
Zfish   187 FIHSSHLNEHMMIHTGEKPFTCTQCGRSFSLSSTLNRHMRIHTGEKPFTCTQCGKSFSQSASLNR 251

  Fly   430 HQRTHSGIKPFKCEECGQAFSHNHHLKSHLRIHTGEKPYKCDQCGKGFSANQSLMKHTLWHVDNN 494
            |.|.|:|..||.|.:||::||.:.:|..|:||||||||:.|.:|||.|..:..|.:|.:.|  |.
Zfish   252 HMRIHTGESPFTCTQCGKSFSLSSYLNKHMRIHTGEKPFICTRCGKSFRHSSHLNQHMMIH--NR 314

  Fly   495 DRPFKCSQCPKAYDTQQSLRGHEKTHKNPDEPKTLHQCPHCDVRFALKKTLDKHITSHKIRPHPC 559
            ::||.|:.|.|::....||..|.:.|.. ::|.|   |..|...|:|.....:|:..|.:|.:.|
Zfish   315 EKPFTCTCCGKSFRHSSSLNQHMRIHTG-EKPFT---CTQCGKSFSLSSYFKRHMKIHSVRDYMC 375

  Fly   560 PQCPEGFFSQKSLKKHLRLH 579
            .:|.:.|.:...||:|.|:|
Zfish   376 LECEKTFITAAELKRHQRIH 395

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
MeicsNP_524062.1 zf-AD 21..95 CDD:285071
C2H2 Zn finger 242..262 CDD:275368 7/19 (37%)
C2H2 Zn finger 274..294 CDD:275368 7/19 (37%)
zf-H2C2_2 287..311 CDD:290200 10/23 (43%)
C2H2 Zn finger 302..322 CDD:275368 7/19 (37%)
C2H2 Zn finger 330..350 CDD:275368 8/19 (42%)
zf-H2C2_2 342..366 CDD:290200 10/23 (43%)
C2H2 Zn finger 358..378 CDD:275368 6/19 (32%)
C2H2 Zn finger 386..406 CDD:275368 7/19 (37%)
COG5048 <395..583 CDD:227381 67/185 (36%)
zf-C2H2 412..434 CDD:278523 8/21 (38%)
C2H2 Zn finger 414..434 CDD:275368 7/19 (37%)
zf-H2C2_2 426..451 CDD:290200 10/24 (42%)
C2H2 Zn finger 442..462 CDD:275368 8/19 (42%)
zf-H2C2_2 454..478 CDD:290200 14/23 (61%)
C2H2 Zn finger 470..486 CDD:275368 6/15 (40%)
C2H2 Zn finger 500..520 CDD:275368 6/19 (32%)
C2H2 Zn finger 532..552 CDD:275370 5/19 (26%)
C2H2 Zn finger 559..579 CDD:275370 7/19 (37%)
zgc:174646NP_001116087.1 C2H2 Zn finger 68..88 CDD:275368 7/19 (37%)
zf-H2C2_2 81..105 CDD:290200 9/27 (33%)
C2H2 Zn finger 96..116 CDD:275368 7/19 (37%)
zf-H2C2_2 108..132 CDD:290200 10/23 (43%)
C2H2 Zn finger 124..144 CDD:275368 7/19 (37%)
COG5048 <129..391 CDD:227381 98/267 (37%)
zf-H2C2_2 137..161 CDD:290200 10/23 (43%)
C2H2 Zn finger 152..172 CDD:275368 8/19 (42%)
zf-H2C2_2 164..187 CDD:290200 10/22 (45%)
C2H2 Zn finger 180..200 CDD:275368 6/19 (32%)
zf-H2C2_2 192..216 CDD:290200 9/23 (39%)
C2H2 Zn finger 208..228 CDD:275368 7/19 (37%)
zf-H2C2_2 221..245 CDD:290200 11/23 (48%)
C2H2 Zn finger 236..256 CDD:275368 7/19 (37%)
zf-H2C2_2 248..272 CDD:290200 9/23 (39%)
C2H2 Zn finger 264..284 CDD:275368 8/19 (42%)
zf-H2C2_2 276..301 CDD:290200 15/24 (63%)
C2H2 Zn finger 292..312 CDD:275368 7/19 (37%)
C2H2 Zn finger 320..340 CDD:275368 6/19 (32%)
zf-H2C2_2 332..356 CDD:290200 8/27 (30%)
C2H2 Zn finger 348..368 CDD:275368 5/19 (26%)
C2H2 Zn finger 375..395 CDD:275368 7/19 (37%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
00.000

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