DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG32137 and Trak2

DIOPT Version :9

Sequence 1:NP_729935.1 Gene:CG32137 / 39537 FlyBaseID:FBgn0052137 Length:620 Species:Drosophila melanogaster
Sequence 2:XP_036009516.1 Gene:Trak2 / 70827 MGIID:1918077 Length:932 Species:Mus musculus


Alignment Length:582 Identity:115/582 - (19%)
Similarity:217/582 - (37%) Gaps:175/582 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    72 GFDHLDYSSLIGDSIDLEHYISAMEARRHDQEPDVWAQLQQKESDILLAAELGKALLEKNEELVK 136
            |.|.::..:...:.||:..::                 |.:::.|:.|||.:|:|||::|..|.:
Mouse    98 GTDRVEQMTKTYNDIDMVTHL-----------------LAERDRDLELAARIGQALLKRNHVLSE 145

  Fly   137 QQEKLIEDYSSKIEKLEQEKHVLRQK------LAIAEDESD------------------------ 171
            |.|.|.|......:::.|.:|.|.:|      ::||.:||:                        
Mouse   146 QNEALEEQLGQAFDQVNQLQHELSKKDELLRIVSIASEESETDSSCSTPLRFNESFSLSQGLLQL 210

  Fly   172 ----QRVLELQSDLTELKDKLQTQD-------TAIRQAE----KEKTILIDELQHQNTRLTEQIQ 221
                :::.||:.:...|:.|:|...       .|:..||    |.:|...:|.:.|  .:.:.::
Mouse   211 DMLHEKLRELEEENMALRSKVQFASLSSNALWAALGDAEACHIKTETFTYEEKEQQ--LVNDCVK 273

  Fly   222 EAHATELKLSAQIQELKDQYHYRNSSL---QEHVNSLES----IKTELNLTTGKRQELERRLQIA 279
            |...|..::|...:||..    ::..|   ||.::||.|    ::.:|.....:::||...||.:
Mouse   274 ELRETNAQMSRMTEELSG----KSDELLRYQEEISSLLSQIVDLQHKLKEHVIEKEELRLHLQAS 334

  Fly   280 QEEKESLTSSLEESSDR-------IHMLERHAREQETKLETTLQALERSQRENNVLSERLGADTN 337
            ::.:..||..|.|..||       :|..:...:|..:|...:.. |..||.......|.|.|:..
Mouse   335 KDAQRQLTMELHELQDRNMECLGMLHESQEEIKELRSKSGPSAH-LCFSQSYGVFTGESLAAEIE 398

  Fly   338 SSTPGRKSLQFEMECDEDDGSYTETGKPNQMFVEARSVYIQLKSLVDSLKVSHDD-DSGLNSDIS 401
            .:.  ||.|..    ||:..|..:.               |.|.:.|::||::|. ...:...:.
Mouse   399 GTM--RKKLSL----DEESVSKQKA---------------QQKRVFDTVKVANDTRGRSVTFPVL 442

  Fly   402 LEL--ESMDNTISSSERHEDGHLAIEFRQGML----------------------SSMSDELTRLL 442
            |.:  .:..:.|.:::..|.|....|.:..:.                      |.::..|.||.
Mouse   443 LPIPGSNRSSVIMTAKPFESGVQPAEDKTLLSPGGSTEVPGNSQPTNPPGSPEDSDLATALHRLS 507

  Fly   443 LNLDAGNFKKMLDQTRNLVLEQE---DEIKRSHQLIQQLEAKVTVTDVELQNVKEERDQARGDLE 504
            |            :.:|.:.|::   :|.:|..|::.:.|.:|:..|...:|:.    ....|..
Mouse   508 L------------RRQNYLSEKQFFAEEWERKIQILAEQEEEVSSCDAPTENLA----SVCTDQS 556

  Fly   505 DNTDRDELLSKAQTERDAANDRRTKAEVELAKTRVELMQANSQLLESIQQKVELSQQLEQWQ 566
            :.||    |..|...|.                   .|....|:::.:    |.||.|..||
Mouse   557 ETTD----LGSASCLRG-------------------FMPEKLQIVKPL----EGSQTLHHWQ 591

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG32137NP_729935.1 DUF4337 <105..>172 CDD:290935 23/100 (23%)
Trak2XP_036009516.1 HAP1_N 50..372 CDD:398490 63/296 (21%)
Milton 433..584 CDD:403594 28/193 (15%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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