DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32137 and Spdl1

DIOPT Version :9

Sequence 1:	NP_729935.1	Gene:	CG32137 / 39537	FlyBaseID:	FBgn0052137	Length:	620	Species:	Drosophila melanogaster
Sequence 2:	NP_081687.2	Gene:	Spdl1 / 70385	MGIID:	1917635	Length:	608	Species:	Mus musculus

Alignment Length:	498	Identity:	111/498 - (22%)
Similarity:	211/498 - (42%)	Gaps:	100/498 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   109 QLQQKESDILLAAELGKALLEKNEELVKQQEKLIEDYSSKIEKLEQEKHVLRQKLAIAEDESDQR 173
            :|::.|.:.|.||..|..|||:..||..|.:|..|:.....||..||||.|::::.:.....|..
Mouse    11 KLKECEDERLKAAHYGLQLLERQTELQSQLDKCHEEMMITAEKYNQEKHALQREVELKSRMLDSL 75

  Fly   174 VLELQSDLTELKDKLQTQDTAIRQAEKEKTILIDELQHQNTRLTEQIQEAHATELKLSAQIQELK 238
            ..|.::...:.|.:|:..:..:.::.:::   :.:|:::...|..::.||...|.:|..::....
Mouse    76 SCECEALKQQQKAQLEQLEVQLHRSHRQE---VSDLKNKLENLKVELDEARLGEKQLKQKLDLQG 137

  Fly   239 DQYHYRNSSL-----QEHVNSLES----IKTELNLTTGKRQELE---RRLQIAQEEKESLTSSLE 291
            :...:::..|     |..::|:.|    ::|||....|.:..|:   ..||..||:.|.|.:||.
Mouse   138 ELLAHKSEELRLLSEQRVLSSMSSELLALETELTAAEGVKNALKEEVNELQYKQEQLECLNTSLL 202

  Fly   292 ESSDRIHMLERHAREQETKLETTLQALERSQRENNVLSERLG------ADTNSSTPGRKSLQFEM 350
            ...||   |:....|:|.:..:...|||:::.||..|..:||      ||.||
Mouse   203 HQVDR---LKEEKEEREREAVSYYNALEKARVENQDLQVQLGHALQQAADPNS------------ 252

  Fly   351 ECDEDDGSYTETGKPNQMFVEARSVYIQLKSLVDSLKVSHDDDSGLNSDISLELESMDNTISSSE 415
                         |.|.:|.|.....:.::..::.:|..:......|:....::..|...||:..
Mouse   253 -------------KGNSLFAEVEDRRVAMERQLNLMKDKYQSLKKQNAFTRDQMNKMKLQISTLL 304

  Fly   416 RHEDGHLAIEFRQ-----GMLSSMSDELTRLLLNLDAGNFKKMLDQTRNLVLEQEDEIKRSHQLI 475
            |.....  .||.|     .|:...:.|:..||     |...| |::.:|              |.
Mouse   305 RMRGSQ--TEFEQQERLFAMIEQKNGEIKHLL-----GEINK-LEKFKN--------------LY 347

  Fly   476 QQLEAKVTVTDVELQNVKEERDQARGDLEDNTDRDELLSKAQTERDAANDRRTKAEVELAKTRVE 540
            :.:|::.:.:|....            |||:|...:||   |.:.|..|......:.||:   ::
Mouse   348 ESMESRPSTSDTACV------------LEDSTYYSDLL---QLKLDKLNKENESTKDELS---IQ 394

  Fly   541 LMQANSQLLESIQQKVELSQQL--EQWQMDMHELIDEQMRSKL 581
            .|:|   |.|| |:.:::.::|  .:..:.:.|..:.::|:||
Mouse   395 RMKA---LFES-QRALDIERKLFTNERHLQLSESENMKLRAKL 433

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32137	NP_729935.1	DUF4337	<105..>172	CDD:290935	21/62 (34%)
Spdl1	NP_081687.2	Smc	<1..344	CDD:224117	85/371 (23%)
Spdl1	NP_081687.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	465..487
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR32123
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100