DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32137 and bicdl2

DIOPT Version :9

Sequence 1:	NP_729935.1	Gene:	CG32137 / 39537	FlyBaseID:	FBgn0052137	Length:	620	Species:	Drosophila melanogaster
Sequence 2:	XP_031748457.1	Gene:	bicdl2 / 448330	XenbaseID:	XB-GENE-5747721	Length:	493	Species:	Xenopus tropicalis

Alignment Length:	595	Identity:	159/595 - (26%)
Similarity:	277/595 - (46%)	Gaps:	108/595 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 IVGGSSSSSSGGNKSKRPRQFGQYSIGVGTGAGAGGLLRSDDSGFDHLDYSSLIGDSIDLEHYIS 93
            :..|.:.|..||         .:|   :|:....|||  :..|..:|. |..|:..|   ..|:.
Frog     1 MTSGGADSHEGG---------AEY---LGSMGWNGGL--TSPSMEEHF-YPFLMERS---PSYMG 47

  Fly    94 AMEARRHDQEPDVWAQLQQKESDILLAAELGKALLEKNEELVKQQEKLIEDYSSKIEKLEQEKHV 158
            ..|....|:  |:...|::|:.|:||||||||||||:|::|:|.::.|.|:....:|.:|||||.
Frog    48 EDEEEHGDE--DLSLVLERKDKDLLLAAELGKALLERNDQLMKAKDALEEELRETLEMIEQEKHN 110

  Fly   159 LRQKLAIAEDESDQRVLELQSDLTELKDKLQTQDTAIRQAEKEKTILIDELQHQNTRLTEQIQEA 223
            :|.|:.:.|.|...:|.:|:|||.|.:.::|...:..|:..:|....:.||..||.||.||:.:|
Frog   111 MRLKMEVQESEWRAQVADLESDLAEARLQMQQLLSEQRECGRESASAVQELSEQNQRLVEQLAQA 175

  Fly   224 HATELKLSAQIQELKDQYHYRNSSLQEHVNSLESIKTELNLTTGKRQELERRLQIAQEEKESLTS 288
            ...|..::.:::.||::......|..:....|:|:::|..|...|::|:|.:.:..|||.:::.:
Frog   176 SQVEQAITLEMKSLKEENRDLTISRGQFAPCLQSLRSENALLLEKKKEMESQTKQLQEENDNVQN 240

  Fly   289 SLEESSDRIHMLERH---AREQETKLETTLQALERSQRENNVLSERLGADTNSSTPGRKSLQFEM 350
            .|..:.:.:..|:|.   |:.|..:||...|.|..||
Frog   241 QLISAKEGVFQLQRQKEDAKSQVLQLELEAQKLRDSQ---------------------------- 277

  Fly   351 ECDEDDGSYTETGKPNQMFVEARSVYIQLKSLVDSLKVSHDDDSGLNSDISLELESMDNTISSSE 415
                                  |::.:|||.|.|.|.:.....|...:..||..|...:|:  .:
Frog   278 ----------------------RTLQLQLKELQDELHMRDSQFSMRGTHSSLHSEIQQSTV--GQ 318

  Fly   416 RHEDGHLAIEFRQGMLSSMSDELTRLLLNLDAGNFKKMLDQTRNLVLEQEDEIKRSHQLIQQLEA 480
            .||.|..:.| .|.:.|...|..              :.::..:|:.|.|::..|       |:.
Frog   319 NHEMGRNSAE-TQSITSDYMDTY--------------LTEREGDLLRENEEQTVR-------LQD 361

  Fly   481 KVTVTDVELQNVKEERDQARGDLEDNTDRDELLSKAQTERDAANDRRTKAEVELAKTRVELMQAN 545
            :||:..:|:.::::|..:.: ||....:.|..:.:|..:||.|..::.:.|.|||:.::|....|
Frog   362 QVTMQHIEITDLRKEVQRLK-DLLQQNNADSTVKQAVLDRDEALMKKAELEQELARCQIEKESLN 425

  Fly   546 SQLLESIQQKVELSQQLEQWQMDMHELIDEQMRSKLINNRRAMAAESSAPSPPSSAAANLAKRVT 610
            .|||.:|||||.|||:||.||.||..:|::|::|:         .:.....||.|...:..:|.:
Frog   426 LQLLSTIQQKVMLSQELEAWQDDMQIVINQQLQSQ---------KQQETQKPPESPQNSFLRRDS 481

  Fly   611 SY-KLWSLFQ 619
            .. |:.|.|:
Frog   482 KRGKILSFFK 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32137	NP_729935.1	DUF4337	<105..>172	CDD:290935	31/66 (47%)
bicdl2	XP_031748457.1	SMC_prok_A	<104..407	CDD:274009	87/377 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D269681at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR32123
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4483
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.050