Protein Alignment CG32137 and Myo18a

DIOPT Version :9

• Sequence 1: NP_729935.1
• Gene: CG32137 / 39537
• FlyBaseID: FBgn0052137
• Length: 620
• Species: Drosophila melanogaster
• Sequence 2: XP_036012684.1
• Gene: Myo18a / 360013
• MGIID: 2667185
• Length: 2493
• Species: Mus musculus
• Alignment Length: 627
• Identity: 137/627 - (21%)
• Similarity: 243/627 - (38%)
• Gaps: 212/627 - (33%)

  Fly   128 LEKNEELVKQQEKLIEDYSSKIEKLEQEKHVLRQKLAIAEDESDQRVLELQSDLT------ELKD 186
            ::.:||.::.:::.|:...||:||:|:|::.||    ::.|..:.|:.||.|:||      |...
Mouse  1300 VQLSEEQIRNKDEEIQQLRSKLEKVEKERNELR----LSSDRLETRISELTSELTDERNTGESAS 1360

  Fly   187 KLQTQDTAIR-QAEKEKTILIDELQHQNTRLTEQ--IQEAHATELKL--SAQI------------ 234
            :|...:||.| :.|||    :.|||.|...|.:|  :.|....|.:|  :|:|
Mouse  1361 QLLDAETAERLRTEKE----MKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGE 1421

  Fly   235 --------------------QELKDQYHYRNSSLQEHVNSLESIKTELNLTTGKRQELERRLQIA 279
                                |||:|:......|.::....|..::.:.:.:....|:|:::.|..
Mouse  1422 WRLKYERAVREVDFTKKRLQQELEDKMEVEQQSRRQLERRLGDLQADSDESQRALQQLKKKCQRL 1486

  Fly   280 QEEKESLTSSLEESSDRIHMLERHAREQETKL-----ETTLQALERS--QRENNVL--------- 328
            ..|.:.....||....|.|.||:..|..:::|     ||..:.|:|.  |||.::|
Mouse  1487 TAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEETQREKLQREKLQREKDMLLAEAFSLKQ 1551

  Fly   329 --------------------------SERLGADTNSSTPGRKSLQ--------FEMECDEDDGSY 359
                                      |.:...|..|....:|.|:        .|.|.||..||.
Mouse  1552 QMEEKDLDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGSI 1616

  Fly   360 TETGKPNQMFVEARSVYIQLKSLVDSLKVSHDDDSGLNSDISLELESMDNTISSS---------- 414
                   ||..:|:   ::|:..::.::.:|          |.|:||.|..:..:
Mouse  1617 -------QMLEQAK---LRLEMEMERMRQTH----------SKEMESRDEEVEEARQSCQKKLKQ 1661

  Fly   415 ------ERHEDGHLAIEFR---QGMLSSMSDEL-----------------TRLLLNLDAGNFKKM 453
                  |.:||...|:..:   :..||::||::                 |:.|| .||   :.|
Mouse  1662 MEVQLEEEYEDKQKALREKRELESKLSTLSDQVNQRDFESEKRLRKDLKRTKALL-ADA---QIM 1722

  Fly   454 LDQTRNLV------------LEQ---------------EDEIKRSHQLIQQLEAKVTVTDVELQN 491
            ||..:|..            ||:               |.|::..|..|..:....|..:.:|..
Mouse  1723 LDHLKNNAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEMEDLHLQIDDIAKAKTALEEQLSR 1787

  Fly   492 VKEERDQARGDL-EDNTDRDELLSK-----AQTERDAANDRRTKAEVELAKTRVELMQANSQLLE 550
            ::.|:::.:..| ||..|.:||:.|     ||..||.|.....:|::|                |
Mouse  1788 LQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDMAQMNDLQAQIE----------------E 1836

  Fly   551 SIQQKVELSQQLEQWQMDMHELIDEQMRSK-LINNRRAMAAE 591
            |.::|.||.::|:..|..: |.:::.|..| |::.:.|...|
Mouse  1837 SNKEKQELQEKLQALQSQV-EFLEQSMVDKSLVSRQEAKIRE 1877

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32137	NP_729935.1	DUF4337	<105..>172	CDD:290935	12/43 (28%)
Myo18a	XP_036012684.1	PDZ_signaling	220..308	CDD:238492
		COG5022	429..1950	CDD:227355	137/627 (22%)
		MYSc_Myo18	467..1224	CDD:276837
		MDN1	<1782..2121	CDD:227596	29/113 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910