DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32137 and Spdl1

DIOPT Version :9

Sequence 1:	NP_729935.1	Gene:	CG32137 / 39537	FlyBaseID:	FBgn0052137	Length:	620	Species:	Drosophila melanogaster
Sequence 2:	NP_001029310.1	Gene:	Spdl1 / 303037	RGDID:	1306908	Length:	597	Species:	Rattus norvegicus

Alignment Length:	499	Identity:	120/499 - (24%)
Similarity:	205/499 - (41%)	Gaps:	106/499 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   109 QLQQKESDILLAAELGKALLEKNEELVKQQEKLIEDYSSKIEKLEQEKHVLRQKLAIAEDESDQR 173
            :|::.|.:.|.||:.|..|||:..||..|.:|..|:..:..|...|||:.|            ||
  Rat    11 KLKECEDERLKAAQYGLQLLERQTELQSQLDKCHEEMMTTAENYNQEKYAL------------QR 63

  Fly   174 VLELQSDLTELKDKLQTQDTAIRQAEKEKTILIDELQHQNTR------------LTEQIQEAHAT 226
            .:||:|.:.|   .|..:..|:||.:|.:...::...|::.|            |..::.||..:
  Rat    64 EVELKSRMLE---SLSCECEALRQQQKAQLEQLEMQLHRSHRQEVHGLRNKLENLKVELDEARLS 125

  Fly   227 ELKLSAQIQELKDQYHYRNSSLQ--------EHVNS-LESIKTELNLTTGKRQELE---RRLQIA 279
            |.:|..::....:...:::..|:        ..|:| |.|::|||....|.:..|.   ..||..
  Rat   126 EKQLKQKLDHQGELLSHKSEELRLLSEQRALSSVSSELLSLQTELTEAEGVKNALREEVNELQCK 190

  Fly   280 QEEKESLTSSLEESSDRIHMLERHAREQETKLETTLQALERSQRENNVLSERLG------ADTNS 338
            ||:.|.|.:||....||   |:....|:|.:..:...|||:::.||..|..:||      ||.||
  Rat   191 QEQLECLNASLLHQVDR---LKEEKEEREKEAVSYYNALEKARVENQDLQVQLGHALQQAADPNS 252

  Fly   339 STPGRKSLQFEMECDEDDGSYTETGKPNQMFVEARSVYIQLKSLVDSLKVSHDDDSGLNSDISLE 403
                                     |.|.:|.|.....:.::..::.:|..:......|:....:
  Rat   253 -------------------------KGNSLFAEVEDRRVAMERRLNLMKDKYQSLKKQNAFTRDQ 292

  Fly   404 LESMDNTISSSERHEDGHLAIEFRQ-----GMLSSMSDELTRLLLNLDAGNFKKMLDQTRNLVLE 463
            :..|...||:..|.....  .||.|     .||...:.|:..||     |...| |::.:||...
  Rat   293 MNKMKLQISTLLRMRGSQ--TEFEQQERLFAMLEQKNGEIKHLL-----GEINK-LEKFKNLYEN 349

  Fly   464 QEDEIKRSHQLIQQLEAKVTVTD---VELQNVKEERDQARGDLEDNTDRDELLSKAQTERDA--- 522
            .|.:...|.... .||.....||   ::|..:.:|.:..:|:|  :..|.:.|.::|...|.
  Rat   350 MESKSSTSDSAC-ALEDSTYYTDLLQLKLDKLNKENESTKGEL--SIQRMKALFESQRTLDIERK 411

  Fly   523 --ANDRRTK-AEVELAKTRVELMQANSQLLESIQQKVELSQQLE 563
              ||:|..: :|.|..|.|.:        |:.::.|.|..:::|
  Rat   412 LFANERHLQLSESENLKLRAK--------LDELKLKYEPEERIE 447

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32137	NP_729935.1	DUF4337	<105..>172	CDD:290935	19/62 (31%)
Spdl1	NP_001029310.1	DUF342	<265..351	CDD:302792	19/93 (20%)
Spdl1	NP_001029310.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	531..597
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR32123
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100