DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DCTN1-p150 and clip3

DIOPT Version :9

Sequence 1:	NP_524061.1	Gene:	DCTN1-p150 / 39536	FlyBaseID:	FBgn0001108	Length:	1265	Species:	Drosophila melanogaster
Sequence 2:	XP_005157797.1	Gene:	clip3 / 562450	ZFINID:	ZDB-GENE-131127-193	Length:	539	Species:	Danio rerio

Alignment Length:	158	Identity:	49/158 - (31%)
Similarity:	71/158 - (44%)	Gaps:	35/158 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSEKNLKVGARVELTGKDLLGTVAYVGMTSFAVGKWVGVVLDEPKGKNSGSIKGQQYFQCDENCG 65
            :|...||:|.||.| .:...||:.:.|.|.||.|:|||:.||||:|||.||:.|.:||.|....|
Zfish   277 LSSLGLKLGDRVVL-DETKTGTLRFCGTTEFASGQWVGLELDEPEGKNDGSVGGIRYFICSAKQG 340

  Fly    66 MFVRPTQL-RLLEAAPGSRRSIEDVSGATPTAAQPTKARLSSSRTSLSSSRQSLLGSRTQLTTSL 129
            :|...::: :.:|..|.|            ..:.|...|:..||.:....::.....|
Zfish   341 IFAPVSKITKAVEQTPSS------------VTSTPKTPRMDLSRVTGKIKKEKKEKDR------- 386

  Fly   130 SERTASSSSIGPRK------SLAPQNSK 151
             |:|       |||      ||.|...|
Zfish   387 -EKT-------PRKKSLSGVSLDPDGVK 406

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DCTN1-p150	NP_524061.1	CAP_GLY	8..74	CDD:214997	29/66 (44%)
DCTN1-p150	NP_524061.1	Dynactin	553..834	CDD:289240
clip3	XP_005157797.1	ANK	100..222	CDD:238125
		ANK repeat	108..145	CDD:293786
		Ank_2	110..216	CDD:289560
		ANK repeat	147..178	CDD:293786
		ANK repeat	186..216	CDD:293786
		CAP_GLY	285..348	CDD:279625	29/63 (46%)
		CAP_GLY	410..473	CDD:279625
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910