DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DCTN1-p150 and Clip3

DIOPT Version :9

Sequence 1:	NP_524061.1	Gene:	DCTN1-p150 / 39536	FlyBaseID:	FBgn0001108	Length:	1265	Species:	Drosophila melanogaster
Sequence 2:	NP_001100971.1	Gene:	Clip3 / 308493	RGDID:	1306245	Length:	547	Species:	Rattus norvegicus

Alignment Length:	153	Identity:	48/153 - (31%)
Similarity:	78/153 - (50%)	Gaps:	19/153 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSEKNLKVGARVELTGKDLLGTVAYVGMTSFAVGKWVGVVLDEPKGKNSGSIKGQQYFQCDENCG 65
            :|...|::|.||.|.|:. .||:.:.|.|.||.|:||||.||||:|||.||:.|.:||.|....|
  Rat   289 LSALGLRLGDRVLLDGQK-TGTLRFCGTTEFASGQWVGVELDEPEGKNDGSVGGVRYFICPPKQG 352

  Fly    66 MFVRPTQL-RLLEAAPGSRRSIEDVSGATPTAAQPTKARLSSSRTSLSSSRQSLLGSRTQLTT-- 127
            :|...::: :.::|.|.|            ..:.|...|:..||.: ...|:...|.:...::
  Rat   353 LFASVSKVSKAVDAPPSS------------VTSTPRTPRMDFSRVT-GKGRREHKGKKKSPSSPS 404

  Fly   128 --SLSERTASSSSIGPRKSLAPQ 148
              ||.:|..:.:.:|.:..:|.|
  Rat   405 LGSLQQREGAKAEVGDQVLVAGQ 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DCTN1-p150	NP_524061.1	CAP_GLY	8..74	CDD:214997	31/66 (47%)
DCTN1-p150	NP_524061.1	Dynactin	553..834	CDD:289240
Clip3	NP_001100971.1	ANK repeat	120..157	CDD:293786
		Ank_2	122..228	CDD:403870
		ANK repeat	159..190	CDD:293786
		ANK repeat	198..228	CDD:293786
		CAP_GLY	296..360	CDD:396049	31/64 (48%)
		CAP_GLY	418..482	CDD:396049	3/10 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5244
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810