DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DCTN1-p150 and clip3

DIOPT Version :9

Sequence 1:	NP_524061.1	Gene:	DCTN1-p150 / 39536	FlyBaseID:	FBgn0001108	Length:	1265	Species:	Drosophila melanogaster
Sequence 2:	NP_001120145.1	Gene:	clip3 / 100145183	XenbaseID:	XB-GENE-5806327	Length:	534	Species:	Xenopus tropicalis

Alignment Length:	148	Identity:	43/148 - (29%)
Similarity:	69/148 - (46%)	Gaps:	12/148 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSEKNLKVGARVELTGKDLLGTVAYVGMTSFAVGKWVGVVLDEPKGKNSGSIKGQQYFQCDENCG 65
            ::...:|:|.|: |...:..||:.:.|.|.||.|:||||.||||:|||.||:.|.:||.|....|
Frog   279 LASLGMKLGDRI-LLDAEKAGTLRFCGTTEFASGQWVGVELDEPEGKNDGSVGGIRYFICPPKQG 342

  Fly    66 MFVRPTQLRLLEAAPGSRRSIEDVSGATPTAAQPTKARLSSSRTSLSSSRQSLLGSRTQLTTSLS 130
            :|           ||.|:.|.......:...:.|...|:..||.:....::.....:..|:....
Frog   343 IF-----------APVSKISKAPDQPPSSVTSTPRTPRVDFSRVTGKGRKEKKATHKKSLSVGSL 396

  Fly   131 ERTASSSSIGPRKSLAPQ 148
            ::......||.:..:|.|
Frog   397 DKEGLKIDIGDQVLVAGQ 414

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DCTN1-p150	NP_524061.1	CAP_GLY	8..74	CDD:214997	29/65 (45%)
DCTN1-p150	NP_524061.1	Dynactin	553..834	CDD:289240
clip3	NP_001120145.1	ANK repeat	110..147	CDD:293786
		Ank_2	112..218	CDD:372319
		ANK repeat	149..185	CDD:293786
		ANK repeat	187..218	CDD:293786
		CAP_GLY	286..350	CDD:366568	32/75 (43%)
		CAP_GLY	405..469	CDD:366568	4/10 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1398
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940