Protein Alignment CG8833 and gpatch1

DIOPT Version :10

• Sequence 1: NP_648669.1
• Gene: CG8833 / 39535
• FlyBaseID: FBgn0036386
• Length: 952
• Species: Drosophila melanogaster
• Sequence 2: NP_001191052.1
• Gene: gpatch1 / 448925
• ZFINID: ZDB-GENE-040914-65
• Length: 975
• Species: Danio rerio
• Alignment Length: 1074
• Identity: 320/1074 - (29%)
• Similarity: 475/1074 - (44%)
• Gaps: 269/1074 - (25%)

  Fly     2 DEEEHLHRFGTPLPALQKDVVPAKKPVAIEDQIVKDENGK-RRFHGAFTGGFSAGFWNTVGSLEG 65
            |.:|....:||||..|::| .|::||:.:.:|.||||.|: :|||||||||||||::|||||.||
Zfish     6 DSDEDFVTYGTPLEPLEED-EPSRKPIPVHEQTVKDEKGRYKRFHGAFTGGFSAGYFNTVGSKEG 69

  Fly    66 WTPQTFKSSRGERASSKAQLKPEDFMDQEDLGEFGIAPQGIRTRDEFANEDEQKQRSDQRRRKLM 130
            |||.||.||| ::.|.|...:||||||:||.||.||||:.|.|.||||:|     |.||.:.|..
Zfish    70 WTPSTFVSSR-QQKSEKHNARPEDFMDEEDFGEHGIAPREITTTDEFASE-----RKDQIKDKAR 128

  Fly   131 QPELGVGAIPGLP-VLEQLLRPVRDKVAVRILKSMGWKPGQGVGPRQTRKEKRQATARNSKEQYL 194
            ........|||.| :||:.:.|.|..:.|.:|:.||||.|||||||..||.::|.|.|
Zfish   129 AVSSLAALIPGDPGLLEEFIAPARSSIGVELLRKMGWKDGQGVGPRLKRKPRKQNTGR------- 186

  Fly   195 MEHYGAEGLPSNKENKGEEDSNNEDED--DEDITFAPDDYEPIFYTPKENRFGMSYSGLNRDPIL 257
              .||. .||.|    |.|:|..:|::  .|::||||.|..|:.:|||.:..|:.|.|||....|
Zfish   187 --VYGC-SLPRN----GSEESEEDDDEFAPENVTFAPKDVVPVDFTPKVDSHGLGYRGLNPLQAL 244

  Fly   258 SKSSSSSAKPMQHI-----------NLFGEMEAQANKKQLSIRGQAFGVGAFEEEDEDIYARDDM 311
            ...|.|.     ||           ||||: .|...:::..|.||||||||.||||.|||.:|.|
Zfish   245 GGGSGSG-----HINLFTLQSDRTTNLFGD-RASGQERRGGIAGQAFGVGAMEEEDGDIYHKDSM 303

  Fly   312 TRYDFSLADKKPKQ------KKQQHVQQRH-----------VIDGFSEDNSPAVLQRPY-AIDLP 358
            :.||..|..::|..      ..||:.::::           ::|||:..:....::..| ..|||
Zfish   304 SNYDNVLGGEEPGDGLYGWTAPQQYTKKKNALKRVMAYSGRILDGFALASEVTEIKTVYPPPDLP 368

  Fly   359 RDFQPRNWLQ---RRSRFAP-----MDKERAQKLETASEYKRSGLGRHDLNPDQRAQILGEQQQE 415
            |||:|.::.:   ..|..:|     :...|.|..:.||:.     |||.|:..||..:|||...:
Zfish   369 RDFRPVHYFRPVIDPSTVSPIVAQALQLSRGQLSQDASQQ-----GRHKLDSTQRRDMLGESALQ 428

  Fly   416 --------------------EKTAEEQPKRNPFKDHSKSLMERINARTEGFTKGGVITENGEEQQ 460
                                .|.||.|   .|.:.:..|.::|.........|...:    :...
Zfish   429 GPSSVFELLESKDRERLTEIRKAAESQ---KPSESNLSSAVDRAVVVASAKAKAAAL----QALS 486

  Fly   461 TELAKEVKEANAAIQERAALKTKDLPSAMNSSSAFKPFIADEAKQLRYEKFVSSKLTDDKEITEF 525
            :.......:.....:.:.||.....|:| ::|..||||..:..||.||:.::|.....||:..|
Zfish   487 SRFQSSSTQPQPPSETQMALNAWSGPTA-DASKTFKPFSKNPQKQARYDLYISKLKQGDKDAVE- 549

  Fly   526 LARMQPVTLSL------WDREMEKKEFIQAAKIYRPLVGLMNDRFV----SEANVQAEKVEQQEK 580
                    |||      |:|..|::||::||.:|:|....::.||.    .|.....:..::||.
Zfish   550 --------LSLDSSMTEWERGREREEFVRAALLYKPSSSSLSSRFTHGKHEEDTDTVDVAQEQEN 606

  Fly   581 PPEERKIVME--------RTKTMWKPTALLCKRYNIAEPFGGAMLEPEKELKAKAKISVFDYLET 637
            ..::::..::        |....|.|..|||||:||.:|:.|:.:....::| :.|.|||::|..
Zfish   607 DVDDKQAAVKMKMFGKLTRDTFEWHPDKLLCKRFNIPDPYPGSSMVGMPKVK-RDKYSVFNFLTI 670

  Fly   638 SVNTKANFETP----SIFPK--------------HIEKSIPEKV------ETPPSPPPAPQPEAE 678
            ...::.|...|    |..|:              .::.|.|:..      ||........|.|||
Zfish   671 PDGSQVNPSDPKPSSSTIPRVTAEASSKKSRWDVPVQASEPKDAVSAFLSETRSEVSATQQTEAE 735

  Fly   679 IQDKPNTKEEPSKHTFVPKTPLEQAV-----------DESRNKPISEKVDLFKSIFEDSDEEETE 732
            :  |..|...|:..|  .:..:.|:|           :|...:.:...:||||:||..|.:|::.
Zfish   736 V--KTQTDALPASAT--SEVKVAQSVEKQSDQKNEEEEEEEEEEVRPSMDLFKAIFASSSDEKSS 796

  Fly   733 LSEQDKLAILQESFGLPVTSTTSAAAQNVLRNTSPPRGIFASLFSPKIKDAAKEPAPTKFGP--- 794
            .|.:|: |..:|....|   |:.||.......|..|                  |.|.:|.|
Zfish   797 SSSEDE-AEEEEELAPP---TSEAAQSTTTSGTVIP------------------PIPAQFTPAPD 839

  Fly   795 ----IEGSKLKIAYKPRKERLRNDREL-----AMAEVAPEDIYGPKLPTAPPQ-KPAAPEIQAEA 849
                ::...|.:...|..|......:.     |.::...|:.:||:||  ||. .|:.
Zfish   840 INKAMDLKHLTVQSVPSAETTAQSTQSSLNAPAKSQGLDEEEFGPRLP--PPGFVPST------- 895

  Fly   850 NIDDRLQQLWQQHAPKKRKAEKWVEKKCISGSEDSDASSSNESSSSDSSDDNDKRSKLSKPKKSH 914
                        |:|:.:|.:|                                     |.|:.|
Zfish   896 ------------HSPQMKKQKK-------------------------------------KDKEKH 911

  Fly   915 KGSSSKKSKKSKLKSKKKSKKSEESKHKAKKKKK 948
            ||...||.||     ||||||   .|||.|:||:
Zfish   912 KGKKHKKEKK-----KKKSKK---HKHKGKQKKR 937

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8833	NP_648669.1	DUF1604	27..112	CDD:462241	54/85 (64%)
		G-patch	154..201	CDD:396249	20/46 (43%)
gpatch1	NP_001191052.1	DUF1604	30..115	CDD:462241	54/85 (64%)
		G-patch	153..>187	CDD:396249	18/42 (43%)