Protein Alignment CG8833 and LOC1280778

DIOPT Version :10

• Sequence 1: NP_648669.1
• Gene: CG8833 / 39535
• FlyBaseID: FBgn0036386
• Length: 952
• Species: Drosophila melanogaster
• Sequence 2: XP_061516755.1
• Gene: LOC1280778 / 1280778
• VectorBaseID: AGAMI1_001024
• Length: 995
• Species: Anopheles gambiae
• Alignment Length: 1085
• Identity: 411/1085 - (37%)
• Similarity: 585/1085 - (53%)
• Gaps: 233/1085 - (21%)

  Fly     2 DEEEHLHRFGTPLPALQKDVVPAKKPVAIEDQIVKDENGKRRFHGAFTGGFSAGFWNTVGSLEGW 66
            |:||.|.|:||.|||.::|.||:|||:.:|||||.|.|||||||||||||||||:||||||.|||
Mosquito     3 DDEETLCRYGTALPAFEEDAVPSKKPITVEDQIVLDSNGKRRFHGAFTGGFSAGYWNTVGSEEGW 67

  Fly    67 TPQTFKSSRGERASSKAQLKPEDFMDQEDLGEFGIAPQGIRTRDEFANEDEQKQRSDQRRRKLMQ 131
            .|..|||||.|::|...|..|.||||:|||||||||||.::.:::||: .....||::||..|
Mosquito    68 KPAEFKSSRTEKSSLARQQNPMDFMDEEDLGEFGIAPQRVQAKEDFAH-SSAAGRSNKRRLDL-- 129

  Fly   132 PELGVGAIPGLPVLEQLLRPVRDKVAVRILKSMGWKPGQGVGPRQTRKEKRQATARNSKEQYLME 196
             ....|.|||.|||..||.|.|:|.||:|||.|||:.|||:|.|||::||::|..|||||||:::
Mosquito   130 -AFSKGPIPGQPVLRALLEPAREKTAVKILKKMGWREGQGIGERQTKREKKRANERNSKEQYILK 193

  Fly   197 HYGAEGLP-------SNKENKGEEDSNNEDEDDED--ITFAPDDYEPIFYTPKENRFGMSYSGLN 252
            .||.| :|       ::.||...:|....|..|.|  |||||||::|:....|:|.||:.||||:
Mosquito   194 MYGCE-IPGREGQTSASAENDDGDDGEESDGSDSDYEITFAPDDFDPLVAALKDNTFGLGYSGLD 257

  Fly   253 RDPILSKSSSSSAKPMQHINLFGEME-AQANKKQLSIRGQAFGVGAFEEEDE-DIYARDDMTRYD 315
            |        ..::|..|   ||..:| ...|.|:|||||||||:||.|::|: |:||||||:|||
Mosquito   258 R--------GGTSKGFQ---LFDTLEVVDRNNKKLSIRGQAFGIGALEDDDDLDVYARDDMSRYD 311

  Fly   316 FSLADKKPKQKK----QQHVQQRHVIDGFSE-DNSPAVLQRPYAIDLPRDFQPRNWLQRRSRFAP 375
            |||.|:. |.|:    ::...:.:.::||.. .:|..:.::.:.:|:|..|:||||.:|||||..
Mosquito   312 FSLEDRS-KSKRAIEGKKSGSEANTLEGFCPVSSSRKLAKKVFRVDVPEVFRPRNWEERRSRFDR 375

  Fly   376 MDKERAQKLETASEYKRSGLGRHDLNPDQRAQILGEQQQEEKTAEEQPKRNPFKDHSKSLMERIN 440
            :|:|||:|::..:|||..|||||||:|.:|..|||||     |..:.|           ::|.||
Mosquito   376 IDEERARKMQQENEYKIKGLGRHDLDPKERGAILGEQ-----TVAKNP-----------VLEMIN 424

  Fly   441 ARTEGFTKGGVITENGEEQQTELAKEVKEANAAIQERAALKTKD------LPSAM---------- 489
            .::..|.:..|:.|..:    .|.:|.|  .||.:|::...:|.      :||.:
Mosquito   425 KQSSNFVRREVMNEVVD----PLPQETK--RAASEEKSGQDSKRDSSPSIVPSGLVQQPSVLQRQ 483

  Fly   490 ---NSSSAFKPFIADEAKQLRYEKFVSSKLTDDKEIT--EFLARMQPVTLSLWDREMEKKEFIQA 549
               ::...||||||...||.|||:|::.:.| ::.:|  ::|..:||:.||.||||.|:|||:||
Mosquito   484 YVGSTKEGFKPFIAMPDKQERYERFLAFQPT-ERYLTREQYLESLQPLNLSAWDRERERKEFMQA 547

  Fly   550 AKIYRPLVGLMNDRFVSEANVQAEKVEQQE----KPPEERKIVMERTKTMWKPTALLCKRYNIAE 610
            .::||||.|||::|||:.:::.|:|....:    ||   |:|.|.|::.||||...:|||:|:.|
Mosquito   548 ERMYRPLDGLMSERFVTASSLIADKTIPADGDAGKP---REIRMTRSRVMWKPHKDICKRFNVPE 609

  Fly   611 PFGGAMLEP----EKELKAKAKISVFDYLETSVNTKANFETPSIFP------------------- 652
            ||||.|::.    ||..|.|.|.|||||||..|..:.:|.||::.|
Mosquito   610 PFGGMMVDDTDAVEKRRKEKGKFSVFDYLEAPVTNRRDFVTPTMIPVAQQVAEDKRPNGGGSKPV 674

  Fly   653 ---------------------------KHIEKSIPEKVETPPSPPPAPQPEAEIQDKPNTKEEPS 690
                                       |.::::....:|.|  .||..|....:..||..|:
Mosquito   675 EQSSGTSTAGQRCSSKDFFLTESTSSAKEVDRNDGVTIEQP--KPPTSQTSRTVPTKPPYKK--- 734

  Fly   691 KHTFVPKTPLEQAVDESRNKPISEKVDLFKSIFEDSDEEETE----------------------- 732
                  :|.||:.|.|:.||...||.|||||||..|||||.|
Mosquito   735 ------RTELEEKVLEATNKKPEEKRDLFKSIFCSSDEEEQEDEQSKNQQSSKPIDGPAAPSGSA 793

  Fly   733 -LSEQDKLAILQESFGLPVTSTTSAAAQNVLRNTSPPRGIFASLFSPKIKDAAKEPAPTKFGPI- 795
             |::::||.:: :||    .|...|:..|:|||.|||||||.:||..|....|.....:|...:
Mosquito   794 ALTDEEKLKMV-DSF----VSIKPASQLNILRNNSPPRGIFKNLFEFKKPQHADGEDRSKRDSVL 853

  Fly   796 -------EGSKLKIAYKPRKERLRNDRELAMAEVAPE--------DIYGPKLPT------AP--- 836
                   .|...:|..:..|:..:||.: :.::..|:        :.|||:||:      ||
Mosquito   854 QCSSKAAAGKAKEILQQAGKDGAKNDTD-SSSDSDPDSASDSDEPEYYGPRLPSQGGANNAPHSK 917

  Fly   837 -PQKPAAPEIQAEANIDDRLQQLWQQHAPKKRKAEKWVEKKCISGSEDSDASSSNESSSSDSSDD 900
             |.:||:..:.:...:         ...|..|..|.|:||                    |:.:|
Mosquito   918 APVEPASHSLLSGREV---------AGTPTGRYTEVWIEK--------------------DAGED 953

  Fly   901 NDKRSKLSKPKKSHKGSSSKKSKKSKLKSKKKSKKSEESKHKAKK 945
            ....|..:|.||.||....|  ||||.|.||:.||| .:|||:|:
Mosquito   954 RHSSSGRAKKKKKHKHHEHK--KKSKGKHKKEKKKS-SNKHKSKR 995

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8833	NP_648669.1	DUF1604	27..112	CDD:462241	58/84 (69%)
		G-patch	154..201	CDD:396249	28/46 (61%)
LOC1280778	XP_061516755.1	None