Protein Alignment dysc and Pdzph1

DIOPT Version :9

• Sequence 1: NP_001261810.1
• Gene: dysc / 39533
• FlyBaseID: FBgn0264006
• Length: 1254
• Species: Drosophila melanogaster
• Sequence 2: NP_081277.1
• Gene: Pdzph1 / 69239
• MGIID: 1916489
• Length: 1238
• Species: Mus musculus
• Alignment Length: 758
• Identity: 150/758 - (19%)
• Similarity: 243/758 - (32%)
• Gaps: 222/758 - (29%)

  Fly   494 GVDKDSVADRSGLMIGDEI----LEVNGQSFLDVTHDEAVGQLKYHKRMSLVIRDVGKVPHSCTS 554
            ||.:..|...:..::|.||    :.....:|:::.|..::|:|..|:|        |.:.|:..
Mouse   212 GVSRSEVPSVNISIVGKEIMVEYISKKQNTFINICHPNSIGKLTKHRR--------GPLKHTTD- 267

  Fly   555 IEMEPWDAYSPTGTRARRKGQIATMVEEKARSLLPRHHFASLSYYIAEYSAKAMTIDAFVAVLLE 619
               ||.::.|..|            :.......|...|.:|.:::.|..|..|:
Mouse   268 ---EPCESASQPG------------INHPENQRLENQHQSSDAFHDAPCSVNAV----------- 306

  Fly   620 MLDTYEKHTLVTEIRELVFPEDRTRYDELVYRRERD--------PYSVDRHRRKGDPARDLPVTA 676
                 :|....|.:..|..|.          |||::        |...:.......|.:.|.:|.
Mouse   307 -----QKENSDTIVVSLSSPP----------RREKEKPNTLPSAPDDSEEGESATSPQKVLQITQ 356

  Fly   677 D-DLEIIAATGRS--PSSDSGLGMTV---TDIYKRPALQLPHRPMSAGPILHRSQPASHYQTGSN 735
            | .||....|..|  |:|...|..|.   .|:.|          ||    |..|:.....:..|:
Mouse   357 DKPLEQHCFTADSCLPTSSETLRTTSLNNVDLSK----------MS----LEDSRDVDEERKNSS 407

  Fly   736 QSSSSLSPPQQQQQQQQHYQPHHASLRHLGGIGGNVGSGRHHHHPLGPSQLKFRQTK-DNQQQEY 799
            ....:::|..|.|..........:::..:..|....||   ...||....|:....| ||.
Mouse   408 DVRENITPDSQVQPCTAGTNGPLSAVNSIIPIQDASGS---EFSPLSFLTLQLLGAKADNM---- 465

  Fly   800 GCDEHRTRRGSETLLPE-YE-------PDAEQEL--------ATKLSRSFDMKEEGGTLLGDK-- 846
            ||      ||.|||..| :|       |.:||..        :.::||..:..|..|......
Mouse   466 GC------RGEETLPGEGHESSNSLLFPVSEQAAKPSPLLSPSHRVSRCSEPVETTGNTFSFSQY 524

  Fly   847 -GVRRHQS------MQRLSAEQNGGSTTEQTHEHNPNVVPDHRGNLHITVKKTKPILGIAIEGGA 904
             ||.|.|.      :.:.|...:..|..:.....:|........:..|.|.|: |:.|
Mouse   525 IGVEREQEKVHYRLINKASLHNDSSSNIQPLERKDPQSPAVTIASCSILVPKS-PLHG------- 581

  Fly   905 NTKHPLPRIINIHENGAAFEAGGLEVGQLILEVDGTKVEGLHHQEVARLIAECFANREKAEITFL 969
                      |||.:        :|..|.....:..:..||...||..:          |.||
Mouse   582 ----------NIHSS--------VEWNQTEDHANHAERAGLSRMEVPVM----------ASIT-- 616

  Fly   970 VVEAKKSNLEPKPTALIFLEAXHLLALPASDPL----ERQKLEFLYEWGIDLTETPKPMPTPIPL 1030
                  :.||.......:.|:    .:.::.|:    .|:...:|...|.|.::.       :|:
Mouse   617 ------NELEQSLATQNYKES----TVDSNSPMAIRNPRESTSYLENVGDDASQA-------LPV 664

  Fly  1031 TK---AKNPPPLPHELHNNINSQYGSSAALSNHQPHQHTHPHPQQQQQQQQHSNTKTPNTNSNKT 1092
            .|   .:|...|..|..|.|.||.......|......||      .::......|...:.:||..
Mouse   665 VKNMCHRNFEDLTRENQNEICSQMDFLQNSSESTSVGHT------TEKLFLIDKTLASDDDSNSN 723

  Fly  1093 QGTPTTGTGAATTGSKQQQQPGNTTNTPTK-----ASREATPTREQHHQHATPT---REHQQQTP 1149
            :...|.|.      :..||:|.....|.::     :..:..||....|    |.   ...|:|..
Mouse   724 RDHKTCGL------NNFQQEPAECQRTTSRVYCEESGNQRYPTEVSCH----PVDILLSPQKQKA 778

  Fly  1150 TRQQQLQ----REQQQQL-----------QREQQQQHHRDRQQ 1177
            .:.|.|:    |:..|:|           |.|..:|..|.|||
Mouse   779 LKDQNLEINNPRKLSQELALRGGRASDGSQEEAIEQWARRRQQ 821

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dysc	NP_001261810.1	PDZ_signaling	294..380	CDD:238492
		PDZ_signaling	466..543	CDD:238492	12/52 (23%)
		HN_L-whirlin_R2_like	573..653	CDD:259823	11/79 (14%)
		PDZ_signaling	886..971	CDD:238492	17/84 (20%)
Pdzph1	NP_081277.1	PDZ_signaling	903..981	CDD:238492
		PH-like	986..1093	CDD:302622
		PH	993..1094	CDD:278594
		PH-like	1123..1215	CDD:302622
		PH	1125..1216	CDD:278594

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900