Protein Alignment dysc and Pdzk1

DIOPT Version :9

• Sequence 1: NP_001261810.1
• Gene: dysc / 39533
• FlyBaseID: FBgn0264006
• Length: 1254
• Species: Drosophila melanogaster
• Sequence 2: NP_113900.1
• Gene: Pdzk1 / 65144
• RGDID: 70924
• Length: 523
• Species: Rattus norvegicus
• Alignment Length: 638
• Identity: 127/638 - (19%)
• Similarity: 220/638 - (34%)
• Gaps: 186/638 - (29%)

  Fly   295 RTVSMSRDQQIDHGFGICVKGGKDSGLGVYISRIEENSVAERAGLRPGDTILEVNGTPFTSINHE 359
            |...:|:.:..::||.:.::...|   |..:..|||.|.||:|||..||.:|.:||   ..::.|
  Rat     8 RECKLSKKEGQNYGFFLRIEKDTD---GHLVRVIEEGSPAEKAGLLDGDRVLRING---VFVDKE 66

  Fly   360 EALKRCVQILKSSRQISMTV----RAPPTLNSTAPLHGFGPPSRDPMYASMAPPLHPQNQAAAAA 420
            |..:....:.||...:::.|    .....:.....|.......|:|......|.|
  Rat    67 EHAQVVDLVRKSGNSVTLLVLDGDSYEKAVKHQVDLKELDQSPREPALNEKKPDL---------- 121

  Fly   421 AAAAASGAGLPFRQTCSWMDRHGRPASPPMEYGGRRSERRDRIRRVELLIEPGQSLGLMIRGGVE 485
                ....|:   :||         |.|.:.|                |::.|.|.|..:: .::
  Rat   122 ----GMNGGV---ETC---------AQPRLCY----------------LVKEGNSFGFSLK-TIQ 153

  Fly   486 YGLGIFVTGVDKDSVADRSGLMIGDEILEVNGQSFLDVTHDEAVGQL-KYHKRMSLVIRDVGKVP 549
            ...|:|:|.:....||.::|::..|.::||||::..:.:|:|.|.:: |...|:..::  |.|..
  Rat   154 GKKGVFLTDITPQGVAMKAGVLADDHLIEVNGENVENASHEEVVEKVTKSGSRIMFLL--VDKET 216

  Fly   550 HSCTSIEMEPWDAYSPTGTRARRKGQIATMVEEKARSLLPRHHFASLSYYI-------------- 600
            ..|.|.:..|:          :|:.....::..:.|.::.:.......:|:
  Rat   217 ARCHSEQKTPF----------KRETASLKLLPHQPRVVVIKKGSNGYGFYLRAGPEQKGQIIKDI 271

  Fly   601 -----AEYSAKAMTIDAFVAVLLEMLDTYEKHTLVTEIRE-------LVFPE--DR----TRYDE 647
                 || :|.....|..|||..|.::..:..::|..||.       ||..:  ||    .|:..
  Rat   272 EPGSPAE-AAGLKNNDLVVAVNGESVEALDHDSVVEMIRNGGDQTTLLVLDKEADRIYSLARFSP 335

  Fly   648 LVYRRERDPYSVDRHRRKGDPARDLPVTADDLEIIAATGRSPSSDSGLGMTVTDIYKRPALQLPH 712
            |:|.:.::   :.....|..||   |::|.    :.|.|.:.:.|.|                .|
  Rat   336 LLYCQSQE---LPNGSVKEAPA---PISAP----LEAPGSATTEDVG----------------DH 374

  Fly   713 RPMSAGPILHRSQPASHYQTGSNQSSSSLSPPQQQQQQQQHYQPHHASLRHLGGIGGNVGSGRHH 777
            :|.....|........|......|..|.:...||                  ||.....|
  Rat   375 KPKLCRLIKEDDSYGFHLNAIRGQPGSFVKEVQQ------------------GGPADKAG----- 416

  Fly   778 HHPLGPSQLKFRQTKDNQQQE-YGCDEHRTRRGSE--TLLPEYEPDAEQELATKLSRSFDMKEEG 839
               |....:......:|.|.| |.....|.:...|  |||          :..|::.|:...::.
  Rat   417 ---LENEDIIIEVNGENVQDEPYDRVVERIKSSGEHVTLL----------VCGKVAYSYFQAKKI 468

  Fly   840 GTL--LGD--------KGVRRHQSMQ------------RLSAEQNGGSTTEQT 870
            ..|  |.|        ||...|.|.:            .|||..:..|.:|.|
  Rat   469 PILSSLADPLVAGPDEKGETEHDSAESTKDSSHPARDRTLSAASHSSSNSEDT 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dysc	NP_001261810.1	PDZ_signaling	294..380	CDD:238492	25/88 (28%)
		PDZ_signaling	466..543	CDD:238492	20/77 (26%)
		HN_L-whirlin_R2_like	573..653	CDD:259823	20/111 (18%)
		PDZ_signaling	886..971	CDD:238492
Pdzk1	NP_113900.1	PDZ_signaling	7..87	CDD:238492	24/84 (29%)
		PDZ	132..212	CDD:214570	22/98 (22%)
		PDZ_signaling	242..320	CDD:238492	14/78 (18%)
		PDZ	375..455	CDD:214570	20/115 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	479..523		10/43 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810