DRSC/TRiP Functional Genomics Resources

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Protein Alignment dysc and GOPC

DIOPT Version :9

Sequence 1:NP_001261810.1 Gene:dysc / 39533 FlyBaseID:FBgn0264006 Length:1254 Species:Drosophila melanogaster
Sequence 2:NP_065132.1 Gene:GOPC / 57120 HGNCID:17643 Length:462 Species:Homo sapiens


Alignment Length:205 Identity:50/205 - (24%)
Similarity:82/205 - (40%) Gaps:56/205 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   360 EALKRCVQILKSS-------------------RQISMTVRAPPTLNSTAPLHGFGPPSRDPMYAS 405
            |||:|.:.:|::.                   :||.:..|         .:.|   |:.|.::..
Human   187 EALRRHIAVLQAEVYGARLAAKYLDKELAGRVQQIQLLGR---------DMKG---PAHDKLWNQ 239

  Fly   406 MAPPLHPQNQAAAAAAAAAASGAGLPFRQTCSWMDRHGRPASPPMEYGG---RRSERRDRIRRVE 467
            :...:|.........|              |...:...||...|..:..   ::|:....||:|.
Human   240 LEAEIHLHRHKTVIRA--------------CRGRNDLKRPMQAPPGHDQDSLKKSQGVGPIRKVL 290

  Fly   468 LLIEPGQSLGLMIRGGVEYGLGIFVTGVDKDSVADR-SGLMIGDEILEVNGQSFLDVTHDEAV-- 529
            ||.|..:.||:.|.||.|:|:.|.::.:.....||| .||.:||.||.|||.:..|..|.|||  
Human   291 LLKEDHEGLGISITGGKEHGVPILISEIHPGQPADRCGGLHVGDAILAVNGVNLRDTKHKEAVTI 355

  Fly   530 -----GQLKY 534
                 |::::
Human   356 LSQQRGEIEF 365

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dyscNP_001261810.1 PDZ_signaling 294..380 CDD:238492 7/38 (18%)
PDZ_signaling 466..543 CDD:238492 30/77 (39%)
HN_L-whirlin_R2_like 573..653 CDD:259823
PDZ_signaling 886..971 CDD:238492
GOPCNP_065132.1 bZIP_2 <166..199 CDD:285017 5/11 (45%)
PDZ_signaling 286..368 CDD:238492 32/80 (40%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 426..449
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3528
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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