Protein Alignment dysc and grip2a

DIOPT Version :9

• Sequence 1: NP_001261810.1
• Gene: dysc / 39533
• FlyBaseID: FBgn0264006
• Length: 1254
• Species: Drosophila melanogaster
• Sequence 2: XP_017212845.1
• Gene: grip2a / 568084
• ZFINID: ZDB-GENE-081104-132
• Length: 1100
• Species: Danio rerio
• Alignment Length: 1153
• Identity: 234/1153 - (20%)
• Similarity: 386/1153 - (33%)
• Gaps: 354/1153 - (30%)

  Fly    28 CDLGPSRWSAR---PY--GYNATAAAAASFGLGPSMGGTQ-------------SSSSVPTGGSAG 74
            |.:|..|...:   ||  |...||:.::.|....|:...|             ||..:...|...
Zfish    45 CRIGVIRGRVKDDVPYTKGSKDTASDSSGFTNRCSLADEQRGVTTVELIKKEGSSLGLTISGGCD 109

  Fly    75 LSGHHLRSSGAPGPSSFEAEDIGMAFGMISPPPGSGPYVGSSAAAGGSRVGNS--TSSLRGAGGR 137
            ..|....|:..||..:..::.:.:           |.|:.|......|::.:.  .|.|:..|.|
Zfish   110 KEGKPRVSNLRPGGLAARSDQLNV-----------GDYIKSVNGINLSKLRHDEIISMLKNIGER 163

  Fly   138 SGL---YYSPPGTSYTIVERPHSPHYYFNSAGVPTKGGSLPGRGSAYLSSSPASHMAAGTAGTLP 199
            ..|   |..||                                   :..|:|.|.::.    |:.
Zfish   164 VVLEVEYELPP-----------------------------------FAPSNPCSVISK----TIE 189

  Fly   200 TSTAASGRSM------GQHASSNGNKKRPISPEQVLRMFGATQSSSVPTSSYHYSNGGTRDRDRT 258
            ......|.|.      |.|  .:.:|.||:                |.|   :...||..||:.|
Zfish   190 VCLEKEGNSFGFVLRGGFH--EDWHKARPL----------------VVT---YVRPGGPADREGT 233

  Fly   259 GRRSPASSPPSTTHQIYRDRERERDRSVPNIHELTTRTVSMSRDQQ----IDHGFGICVKGGKDS 319
            .|   |.....:.:.:..:|::..|          ..|:.|...|:    |::...:.....|.|
Zfish   234 LR---AGDRVLSVNGVAVNRQKHAD----------ALTLIMQSSQEAFFLIEYDIMVMDSVQKSS 285

  Fly   320 G-------------LG-------------VYISRIEENSVAERAG-LRPGDTILEVNGTPFTSIN 357
            |             ||             :.|.:|:..|||:|.| |..||.:|.::|   .|..
Zfish   286 GPLQVDIARSAGSVLGLSLSTSLYRNKQVITIQKIKPASVADRCGALHAGDILLAIDG---MSTE 347

  Fly   358 HEEALKRCVQILKSSRQISM------------TVRAPPTL--------NSTAPLHGFGPPSRDPM 402
            | .:|....|:|.||.:::.            |||...:.        |.|..|..|   .:.|.
Zfish   348 H-CSLMEAQQLLSSSSELTKLEILPSLHSSQDTVRVQRSCQRQWDSSENYTNALPAF---QKTPS 408

  Fly   403 YASMAPPLHPQNQAAAAAAAAAASG---------AGLPFRQTCSWMDRHGRPASPPMEYGGRRSE 458
            ..|...|. |.:::.::..:|..||         :..|.....|.:..:  |:||......||..
Zfish   409 AWSQTTPT-PSHRSVSSGVSANTSGFHSYNCGSQSAYPNTYPSSTLPSY--PSSPRCSATKRRHR 470

  Fly   459 RRD-------------------RIRRVELLI--EPGQSLGLMIRGGVEYGLGIFVTG-------- 494
            |::                   .:...|:|:  :|....||.::|||      |.|.
Zfish   471 RKEHKSSLSLASSTVGAGGQVVHLESAEVLLRGDPLTGFGLQLQGGV------FATEPLSAPAAI 529

  Fly   495 --VDKDSVADRSG-LMIGDEILEVNGQSFLDVTHDEAVGQLKYHKRMSLVIRDVGKVPHSCTSIE 556
              ::.|:.|:|.| |.:||.||.:||....|.|.:||          :.::||..........:|
Zfish   530 RFIEPDTPAERCGVLQVGDRILSINGIPTEDGTLEEA----------NQLLRDAALANKIALEVE 584

  Fly   557 MEPWDAYSP-TGT----RARRKG---QIATMVEEKARS--LLPRHHFASLSYYIA--EYSAKAMT 609
            .:..::..| :||    ..:|:|   .|.....:||..  ::......|:::.|.  |...:.:.
Zfish   585 FDVAESVIPSSGTFQVKLPKRRGVELGITISASKKAGKPLIISEIQKGSIAHRIGTLEPGDRLLA 649

  Fly   610 IDAFVAVLLEMLDTYEKHTLVTEIRELV---FPEDRTRYDEL------VYRRERDPYSVDRHRRK 665
            ||   .|.|:.....|...::.:...:|   ..:|....|||      ::..|.        :|.
Zfish   650 ID---NVRLDNCGMEEAMMVLQQAEGMVKLRIQKDEDNLDELESSGSVIFTVEL--------KRH 703

  Fly   666 GDPARDLPVTADDLE------IIAA---------TGRSPSSDSGLGMTVTDIYKRPALQLPHRPM 715
            |.|   |.:|....|      :|::         ||.....|..|.:....:..:|..:..|...
Zfish   704 GGP---LGITISGTEEPFNPILISSLTRNGLAHRTGALHIGDRVLAINNMSLKGKPLSEAIHLLQ 765

  Fly   716 SAG-----PILHRSQPASHYQTGS-NQSSSSLSPPQQQQQQQQHYQPHHASLRHL---------- 764
            :||     .|..||.|....:.|| ::::|.:|..:..:........:...||..
Zfish   766 TAGDTVTLKIKKRSDPLLDSERGSPSRTASCVSDMEDDRSDSFRRGKYSDLLRQTTPPSLDSAMD 830

  Fly   765 ----GGIGGNVGS-GRHHHHP----LGPSQLKFRQTKDNQQQEYGCDEHR-------------TR 807
                ..:....|| |.:.|.|    |.||.  :|||............||             |.
Zfish   831 SWDSSALDAGYGSQGVYIHRPSDFTLHPSD--WRQTNHRSPLMSRRPAHRPTVYDGRLSEEDWTY 893

  Fly   808 RGSET------------LLPEYEPDAEQELATKLSRSFDMKE------EGGTL-LGDKGVRRHQS 853
            .||.:            ....|...|.|:|.| ..:|..::|      .|.|| ||:...::::|
Zfish   894 SGSVSPACGHNYNSTTDAQENYWSQALQDLET-CGQSEILRELEATIMSGSTLSLGEDFEKQNES 957

  Fly   854 MQR---LSAEQNGGSTTEQTHEHNPNVVPDHRGNLH-ITVKKTKPI--LGIAIEGGANTKHPLPR 912
            ..:   ||.|....:|.|...|::|:|..:    || |.::|....  .|.::..|...|.....
Zfish   958 KTKFLELSPENTSVNTPEDLKENSPSVPLE----LHKICIQKDADSRDFGFSVSDGLLEKGVYVN 1018

  Fly   913 IINIHENGAAFEAGGLEVGQLILEVDGTKVEGLHHQEVARLIAECFAN 960
            :  |..:|.|.:| ||.....||:|:..:...........||.|...|
Zfish  1019 M--IRPDGPADQA-GLRPYDRILQVNHARTRDFDCCLAVPLITEAGEN 1063

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dysc	NP_001261810.1	PDZ_signaling	294..380	CDD:238492	29/128 (23%)
		PDZ_signaling	466..543	CDD:238492	25/89 (28%)
		HN_L-whirlin_R2_like	573..653	CDD:259823	17/95 (18%)
		PDZ_signaling	886..971	CDD:238492	19/78 (24%)
grip2a	XP_017212845.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900