Protein Alignment dysc and ush1c

DIOPT Version :9

• Sequence 1: NP_001261810.1
• Gene: dysc / 39533
• FlyBaseID: FBgn0264006
• Length: 1254
• Species: Drosophila melanogaster
• Sequence 2: XP_009296312.1
• Gene: ush1c / 564412
• ZFINID: ZDB-GENE-060312-41
• Length: 586
• Species: Danio rerio
• Alignment Length: 693
• Identity: 136/693 - (19%)
• Similarity: 243/693 - (35%)
• Gaps: 268/693 - (38%)

  Fly   272 HQIYRDRERERDRSVPNIHELTTRTVSMSRDQQID----HGFGICVKGGKDSGLGVYISRIEENS 332
            ||:..|             :||.:.....::.::|    .|.|:.|:||.:.|.|::||:|.::.
Zfish    70 HQVQYD-------------QLTPKRSRKLKEVRLDRTHPEGLGLSVRGGLEFGSGLFISQIVKDG 121

  Fly   333 VAERAGLRPGDTILEVNGTPFTSINHEEALKRCVQILKSSRQISMTVRAPPTLNSTAPLHGFGPP 397
            .|...||:.||.|:.:||...:|..|||.    :.::|:.:.:|:.||....:
Zfish   122 QAGNVGLQVGDEIVRINGYSISSCIHEEV----INLIKTKKTVSLKVRHVGMI------------ 170

  Fly   398 SRDPMYASMAPPLHPQ--NQAAAAAAAAAASGAGLPFRQTCSWMDRHGRPASPPMEYGGRRSERR 460
               |:.:|...||..|  :|..:.:...:.|.|||                   ...||...:.
Zfish   171 ---PVKSSSDEPLKWQFVDQFVSESGEKSNSIAGL-------------------ASIGGNEIKE- 212

  Fly   461 DRIRRVELLIEPGQSLGLMIRGGVEYGLGIFVTGVDKDSVADRSGLMIGDEILEVNGQSFLDVTH 525
               ::|.|.:...:.:|:.|..|.....||:|:.|...|::...||.:||:|:||||..|.:::|
Zfish   213 ---KKVFLSLVGTKGMGISISSGPTKKPGIYVSNVKPGSLSAEVGLQVGDQIVEVNGVEFTNLSH 274

  Fly   526 DEAVGQLKYHKRMSLVIRDVGKVPHSCTSIEMEPWDAYSPTGTRARRKGQIATMVEEKARSLLPR 590
            .|||..||..:.:::.:.                      ||.     |....|.:|:..::..|
Zfish   275 QEAVRVLKSSRSLTITVL----------------------TGA-----GSELFMTDEERLAVEAR 312

  Fly   591 HHFASLSYYIAEYSAKAMTIDAFVAVLLEMLDTYEKHTLVTEIRELVFPEDRTRYDELVYRRERD 655
            |          |...:.:.....||:        |.:.:|.|.:|    ::|.|..|:..:...:
Zfish   313 H----------ELDRQELMHQKKVAL--------ETNKIVKEQQE----KERQRKMEISQKAAEE 355

  Fly   656 PYSVDRHRRKGDPARDLPVTADDLEIIAATGRSPSSDSGLGMTVTDIYKRPALQLPHRPMSAGPI 720
            .   :|:|:             ::|.|.|..:.
Zfish   356 E---ERYRK-------------EMERIEAAEKK-------------------------------- 372

  Fly   721 LHRSQPASHYQTGSNQSSSSLSP---PQQQQQQQQHYQPHHASLRHLGGIGGNVGSGRHHHHPLG 782
             |..:....:  ||.:...|:||   |......:                             |.
Zfish   373 -HHKEWEDDW--GSKEKKKSVSPAASPSPPPPTR-----------------------------LA 405

  Fly   783 PSQLKFRQTKDNQQQEYGCDEHRTRRGSETLLPEYEPDA---EQELATKLSRSFDMKEEGGTLLG 844
            ||......|.|:.::|.|       .|.:..:.:::|.:   .:::|.:..|...:|:||.
Zfish   406 PSPKPKTSTADSYEEETG-------EGFQKYVDDFDPHSMFTAEQIAGRDVRLLRIKKEGK---- 459

  Fly   845 DKGVRRHQSMQRLSAEQNGGSTTEQTHEHNPNVVPDHRGNLHITVKKTKPILGIAIEGGANTKHP 909
                                                               |.:|||||.::  |
Zfish   460 ---------------------------------------------------LDLAIEGGIDS--P 471

  Fly   910 LPRII--NIHENGAAFEAGGLEVGQLILEVDG------TKVEG 944
            |.:|:  :|:|.|||.:.||:..|..|:.|:|      |..||
Zfish   472 LGKIVVSSIYEGGAADKHGGVVSGDEIMAVNGKILTDVTLAEG 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dysc	NP_001261810.1	PDZ_signaling	294..380	CDD:238492	25/89 (28%)
		PDZ_signaling	466..543	CDD:238492	26/76 (34%)
		HN_L-whirlin_R2_like	573..653	CDD:259823	15/79 (19%)
		PDZ_signaling	886..971	CDD:238492	23/67 (34%)
ush1c	XP_009296312.1	harmonin_N	2..80	CDD:259819	5/22 (23%)
		PDZ_signaling	85..165	CDD:238492	25/83 (30%)
		PDZ_signaling	212..292	CDD:238492	26/83 (31%)
		RILP-like	317..>379	CDD:304877	15/122 (12%)
		PDZ_signaling	447..534	CDD:238492	27/125 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810