Protein Alignment dysc and lnx2a

DIOPT Version :9

• Sequence 1: NP_001261810.1
• Gene: dysc / 39533
• FlyBaseID: FBgn0264006
• Length: 1254
• Species: Drosophila melanogaster
• Sequence 2: NP_001106696.2
• Gene: lnx2a / 553331
• ZFINID: ZDB-GENE-060228-2
• Length: 737
• Species: Danio rerio
• Alignment Length: 591
• Identity: 133/591 - (22%)
• Similarity: 194/591 - (32%)
• Gaps: 188/591 - (31%)

  Fly    60 GTQSSSSVPTGGSAGLSGHHLRSSGAPGPSSFEAEDIGMAFGM-ISPP----PGSGPYV-----G 114
            |:.:.::|||         .....|...|:..|:.:.....|: .:.|    |.|.|.:     |
Zfish   181 GSNACNNVPT---------WTEEPGIDNPAFEESTEEDSVHGLECALPRVKRPLSNPCIHLLRTG 236

  Fly   115 SSAAAGGSRVGNSTSSLRGAGGRSGLYYSPPGTSYTIVERPHSPHYYFNSAGVPTKGGSLPGRGS 179
            |||::|...|  .|..|....|...|...|.|...||.....:|   ::..|:...||
Zfish   237 SSASSGWDFV--ETLPLSAEEGCVKLPSLPEGEITTIEVHRTNP---YSEMGISIVGG------- 289

  Fly   180 AYLSSSPASHMAAGTA---GTLPTSTAASGRSMG---------------QHASSNGNKKRPISPE 226
               :.:|..::.....   |.:    |..||.:.               .|..:.....||.:..
Zfish   290 ---NETPLINVVIQEVYRDGVI----ARDGRLLAGDQILQVNNVDISNVPHNFARSTLARPCATL 347

  Fly   227 QVLRMFGATQSSSVPTSSYHYSNGGTRDRDRTGRRSPASSPPS---TTHQIYRDRERERDRSVPN 288
            |:..:.....|:..|.::                .||..||.|   |.|:    ||......:
Zfish   348 QLTVLRERRCSARPPAAT----------------ASPKGSPASIRITLHK----RESSEQLGI-- 390

  Fly   289 IHELTTRTVSMSRDQQIDHGFGICVKGGKDSGLGVYISRIEENSVAERAG-LRPGDTILEVN--- 349
              :|..||     |:                 .||:|..:.|..:|.:.| |...|.:|.||
Zfish   391 --KLVRRT-----DE-----------------AGVFILDLLEGGLAAKDGRLCSNDRVLAVNEHD 431

  Fly   350 ---GTPFTSINHEEALKRCVQIL--KSSRQISMTVRAPPTLNSTAPLHGFGPPSRDPMYASMAPP 409
               |||..:....:|....|.:|  :||:| :|.|....||......|...||.......|..|.
Zfish   432 LRHGTPELAAQIIQASGERVNLLISRSSKQ-TMAVHTGSTLTRDIWSHDHIPPLPSTATPSPVPS 495

  Fly   410 LHPQNQAAAAAAAAAASGAGLPFRQTCSWMDRHGRPASPPMEYGGRRSERRDRIRRVELLIEPGQ 474
            ||           .|.|.......|..:..::|                       :.:..||.:
Zfish   496 LH-----------LARSSTQRDLSQCVNCKEKH-----------------------ITVKKEPHE 526

  Fly   475 SLGLMIRG--GVEYG-LGIFVTGVDKDSVADRSG-LMIGDEILEVNGQSFLDVTHDEAVGQLKYH 535
            |||:.:.|  |.:.| |.||||.|.......|.| :..||.:|.:|||....::|.||||.||
Zfish   527 SLGMTVAGGRGSKSGELPIFVTSVQPHGCLSRDGRIKRGDVLLSINGQDLTYLSHSEAVGTLK-- 589

  Fly   536 KRMSLVIRDVGKVPHSCTSIEMEPWDAYSPTGTRARRKGQIATMVEEKA--RSLLPRHHFASLSY 598
                                       .|.|....:.|....|||||..  ..|||.|.    :.
Zfish   590 ---------------------------SSATSCSVQLKALEVTMVEEPGLDEELLPPHE----ND 623

  Fly   599 YIAEYS 604
            |.|.:|
Zfish   624 YDASWS 629

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dysc	NP_001261810.1	PDZ_signaling	294..380	CDD:238492	24/94 (26%)
		PDZ_signaling	466..543	CDD:238492	29/80 (36%)
		HN_L-whirlin_R2_like	573..653	CDD:259823	13/34 (38%)
		PDZ_signaling	886..971	CDD:238492
lnx2a	NP_001106696.2	zf-RING_2	49..87	CDD:290367
		PDZ	267..353	CDD:214570	15/102 (15%)
		PDZ_signaling	375..455	CDD:238492	24/109 (22%)
		PDZ_signaling	515..600	CDD:238492	32/136 (24%)
		PDZ_signaling	646..730	CDD:238492

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900