Protein Alignment dysc and Grip

DIOPT Version :9

• Sequence 1: NP_001261810.1
• Gene: dysc / 39533
• FlyBaseID: FBgn0264006
• Length: 1254
• Species: Drosophila melanogaster
• Sequence 2: NP_572285.2
• Gene: Grip / 50391
• FlyBaseID: FBgn0029830
• Length: 1058
• Species: Drosophila melanogaster
• Alignment Length: 1116
• Identity: 206/1116 - (18%)
• Similarity: 320/1116 - (28%)
• Gaps: 505/1116 - (45%)

  Fly    47 AAAASFGLGPSMGGTQSSSSVPTGGSAGLSGHHLRSSGAPGPSSFEAEDIGMAFGMISPPP--GS 109
            |.:...||.|..|.|.::.::|.      :..||..:.|      |..|       :|.||  ||
  Fly    65 AQSEDSGLAPERGTTYATITLPR------NALHLAITFA------ERND-------LSYPPVVGS 110

  Fly   110 GPYVGSSA--AAGGSRV----GNSTSSLRG--------AGGRSG------LYYSPP--------- 145
            ...||.:|  .|.|.|:    |.||..|..        |||...      :.||.|
  Fly   111 LNPVGHAADFLAPGDRLHQIDGISTIGLSNQKVMNMLCAGGSDACPAIVEIEYSLPECTVSQNSL 175

  Fly   146 ------------------------GTSYTIV---ERPHSPHYYFNSAGVPTKGGSLPGRGSAYLS 183
                                    |..|.::   .|||.|.|         |.|.:
  Fly   176 CVTSKLAQITVERESGCLGLTLRGGADYPLIVTHVRPHGPVY---------KTGRI--------- 222

  Fly   184 SSPASHMAAGTAGTLPTSTAASGRSM---GQHASSNGNK-----------------------KRP 222
             .|...:......:|...|.|..:.:   |.|.|...|.                       :||
  Fly   223 -KPGDRLLRVDNVSLIGKTLAEAQQIIKCGGHVSGYTNLTIEYDVSVVQSVEFSMGPLLIEIERP 286

  Fly   223 ISPEQVLRMFGATQSSSVPTSSYHYSNGGTRDRDRTGRRSPASSPPSTTHQIYRDRERERDRSVP 287
            ::.:  |.:.....:::||.|                  ...||.||:..:|
  Fly   287 MNDK--LGLVLCNYTAAVPAS------------------GSGSSTPSSGEKI------------- 318

  Fly   288 NIHELTTRTVSMSRDQQIDHGFGICVKGGKDSGLGVYISRIEENSVAERAG-LRPGDTILEVNGT 351
                                          :...||:|:.|...|:|:|.| |..||.:|.::.|
  Fly   319 ------------------------------EESAGVFIASILPASIADRCGALSVGDQVLSIDDT 353

  Fly   352 --PFTSINHEEALKRCVQILKSSRQISMTVRAPPTLNSTAPLHGFGPPSRDPMYASMAPPLHPQN 414
              ..|:.:.:|.:                     |:..|:...|         |..|      |.
  Fly   354 MIEHTAFSPDEVM---------------------TILDTSTGRG---------YTQM------QI 382

  Fly   415 QAAAAAAAAAASGAGLPFRQTCSWMDRHGRPASPPMEYGGRRSERRDRIRRVELLIE------PG 473
            ..|.|.|....:..|.|   ..|:.....|.:|.    .||:.:|  ..|:..|.:|      ||
  Fly   383 MPAHALARRGHTTLGSP---KYSFSTLESRKSST----AGRQRQR--FARKSSLPLENPACGTPG 438

  Fly   474 QSLGLMIRGGV------------------------EYGLGIF----VTG-----------VDKDS 499
            .:.|.|..||:                        .:|.||.    |:|           :..||
  Fly   439 STGGSMGTGGIHGSSSLGMGLGLCRAESFPVLLDCSHGAGIILSETVSGSGGSGAVAIAQIVPDS 503

  Fly   500 VADRSG-LMIGDEILEVNGQSFLDVTHDEAVGQLKYHKRMSLVIRDVGKVPHSCTS--------- 554
            |||||| :..||.|:.:|....||..   |:.||          .:.|...:..::
  Fly   504 VADRSGCIQAGDRIVAINKMYSLDAA---AMRQL----------LEGGSSRNGASNGTPANWLEL 555

  Fly   555 -IEMEPWDAYSPT-----------------------------------GTRARRKGQIAT----- 578
             ||.:..||..|.                                   |:.|.|.|.:.:
  Fly   556 EIEFDMPDAVVPASGVFSVKLLRAGKCGLGLSVSGSSHGGLVISDVKMGSPAHRSGSLRSGDILL 620

  Fly   579 --------------MVEEKARSLLPRH---HFASLSYYIAEYSAKAMTIDAFV------------ 614
                          :::|:.||..|.|   .|.:|       :.|.:.:..|:
  Fly   621 AVDQHPVQHFNVDALLKEEGRSQNPSHSSSDFTTL-------TIKRIVLPDFLPMSSPIYSNCPA 678

  Fly   615 -AVLLEM---LDTYEKHTLVTEIRELVFPEDRTRYDELVYRRERDPYSVDRHRRKGDPARDLPVT 675
             .:.|.|   :.|...|.|.:......     .:|.:.|..:.|.| ..|..|        :| :
  Fly   679 SGINLGMGMGVSTSTDHDLYSSAYVTA-----GKYADCVSLKSRTP-QPDYFR--------VP-S 728

  Fly   676 ADDLEIIAATGRSPSSDSGLGMTVTDIYKRPALQLPHRPMSAGPILHRSQPASHYQTGSNQSSSS 740
            .||..:.:...||.|..:|                            .:|.|:.:.||.| |.|.
  Fly   729 MDDASLQSVQLRSGSGSNG----------------------------GNQAANSWSTGVN-SRSY 764

  Fly   741 LSPPQQQQQQQQHYQPHHASLRHLGGIGGNVGSGRHHHHPLGPSQLKFRQTKDNQQQEY-GCDEH 804
            ::||..|....:                                   ..:.:|.|:|.| |.:.:
  Fly   765 VAPPNTQSLTTE-----------------------------------LPEEEDEQEQMYPGYELN 794

  Fly   805 RTRRGSETLLPEYEPDAEQELATKLSRSFDMKEEGGTLLGDKGVRRHQSMQRLSAEQNGGSTTEQ 869
            |......|.||   |..|.::....:.| ..|..|.:|        ||.:..:..|..||
  Fly   795 RYASVDCTALP---PPMENKVYGSAASS-SSKSSGSSL--------HQIIFTVRLEPKGG----- 842

  Fly   870 THEHNPNVVPDHRGNLHITVKKTKPILGIAIEGGANTKHPLPRIINIHENGAAFEAGGLEVGQLI 934
                                     :|||.:.|..:....: .|..:.|.|.|.:.|.:.||..:
  Fly   843 -------------------------LLGITLAGSEDITKSI-TISGLVEGGIAHKNGQIHVGDQL 881

  Fly   935 LEVDGTKVEGL 945
            |.:|...|:|:
  Fly   882 LAIDEHSVQGM 892

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dysc	NP_001261810.1	PDZ_signaling	294..380	CDD:238492	15/88 (17%)
		PDZ_signaling	466..543	CDD:238492	30/122 (25%)
		HN_L-whirlin_R2_like	573..653	CDD:259823	17/117 (15%)
		PDZ_signaling	886..971	CDD:238492	15/60 (25%)
Grip	NP_572285.2	PDZ	82..147	CDD:294084	21/83 (25%)
		PDZ_signaling	183..254	CDD:238492	14/89 (16%)
		PDZ_signaling	278..375	CDD:238492	28/180 (16%)
		PDZ	496..>521	CDD:294084	11/24 (46%)
		PDZ_signaling	571..658	CDD:238492	11/93 (12%)
		PDZ_signaling	832..913	CDD:238492	18/92 (20%)
		PDZ_signaling	973..1055	CDD:238492

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900