DRSC/TRiP Functional Genomics Resources

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Protein Alignment dysc and Lnx2

DIOPT Version :9

Sequence 1:NP_001261810.1 Gene:dysc / 39533 FlyBaseID:FBgn0264006 Length:1254 Species:Drosophila melanogaster
Sequence 2:NP_001101799.1 Gene:Lnx2 / 360761 RGDID:1308222 Length:686 Species:Rattus norvegicus


Alignment Length:393 Identity:88/393 - (22%)
Similarity:135/393 - (34%) Gaps:119/393 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly   261 RSPASSPPS--TTHQIYRDRERERDRSVPNIHELTTRTVSMSRDQQIDHGFGICVKGGKDSGL-G 322
            :.|.|.|..  ||.:|:|..        |.|.                  .||.:.||.::.| .
  Rat   220 QQPLSLPEGEITTIEIHRTN--------PYIQ------------------LGISIVGGNETPLIN 258

  Fly   323 VYISRI-EENSVAERAGLRPGDTILEVNGTPFTSINHEEALKRCVQILKSSRQISMTVRAPPTLN 386
            :.|..: .:.::|....|..||.||:||....::::|..|  |.| :.:....:.:||.......
  Rat   259 IVIQEVYRDGAIARDGRLLAGDQILQVNNCDISNVSHNYA--RAV-LSQPCSTLHLTVLRERRFG 320

  Fly   387 STAPLHGFGPPSRDPMYASMAPPLHPQNQA--------------------AAAAAAAAASGA--- 428
            |.|..|..|...||.::..:   ||.::.|                    ......||..|.   
  Rat   321 SRANNHADGSAPRDEVFQVL---LHKRDSAEQLGIKLVRRTDEPGVFILDLLEGGLAAQDGRLSS 382

  Fly   429 --------GLPFRQTCSWMDRH-------------GRPASPPMEYGGRR---------------- 456
                    |...:|....:..|             .||..|....|.|.                
  Rat   383 NDRVLAINGHDLKQGTPELAAHIIQASGERVNLTIARPGKPQPSNGSREAGAHSSNHAQPPSHSR 447

  Fly   457 -SERRDRIR-------RVELLIEPGQSLGLMIRG--GVEYG-LGIFVTGVDKDSVADRSG-LMIG 509
             |..:|..|       .:.:..||.:|||:.:.|  |.:.| |.||||.|.......|.| :..|
  Rat   448 PSSHKDLTRCVTCQEKHITVKKEPHESLGMTVAGGRGSKSGELPIFVTSVPPHGCLARDGRIKRG 512

  Fly   510 DEILEVNGQSFLDVTHDEAVGQLKYHKRMSLVI---RDVGKVPHSCTSIEMEP-------WDA-Y 563
            |.:|.:||....:::|.|||..||.......||   .:|.....:..:.|.:|       :|| :
  Rat   513 DVLLNINGIDLTNLSHSEAVAMLKASAASPAVILKALEVQIAEEAAQATEEQPGAFSENEYDASW 577

  Fly   564 SPT 566
            ||:
  Rat   578 SPS 580

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dyscNP_001261810.1 PDZ_signaling 294..380 CDD:238492 19/87 (22%)
PDZ_signaling 466..543 CDD:238492 29/83 (35%)
HN_L-whirlin_R2_like 573..653 CDD:259823
PDZ_signaling 886..971 CDD:238492
Lnx2NP_001101799.1 mRING-HC-C3HC3D_LNX2 46..90 CDD:319694
PDZ 229..315 CDD:214570 26/114 (23%)
PDZ 335..421 CDD:214570 10/88 (11%)
PDZ_signaling 462..538 CDD:238492 27/75 (36%)
PDZ_signaling 595..679 CDD:238492
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3528
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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