Protein Alignment dysc and CG5921

DIOPT Version :10

• Sequence 1: NP_001261810.1
• Gene: dysc / 39533
• FlyBaseID: FBgn0264006
• Length: 1254
• Species: Drosophila melanogaster
• Sequence 2: NP_727061.2
• Gene: CG5921 / 31538
• FlyBaseID: FBgn0029835
• Length: 886
• Species: Drosophila melanogaster
• Alignment Length: 1079
• Identity: 223/1079 - (20%)
• Similarity: 339/1079 - (31%)
• Gaps: 376/1079 - (34%)

  Fly   200 TSTAASGRSMGQHASSNGNKKRPISPEQVLRMFGATQSSSVPTSSYHYSNGGTRDRDRTGRRSPA 264
            |.||||. |:...||...:.....|..    |.|:|.||         ::........|...|..
  Fly     3 TMTAASA-SISTSASLTNSASTDCSSS----MQGSTTSS---------ASSDVMTLTTTAASSWC 53

  Fly   265 SSPPSTTHQIYR-DRERERDRSVPNIHELTTRTVSMSRDQQIDHGFGICVKGGKDSGLGVYISRI 328
            :.|.|:..::.| .|..:|...|......:|              :|..|:||::.|.|.::|.:
  Fly    54 AIPASSRLRVLRLVRPHQRRLLVGGPERGST--------------YGFTVRGGREHGTGFFVSHV 104

  Fly   329 EENSVAERAGLRPGDTILEVNGTPFTSINHEEALKRCVQILKSSRQISMTVRAPPTLNSTAPLHG 393
            |....|...|||.||.||.:||.......|:|    .:|::....::::.||....|
  Fly   105 EHGGEAHLKGLRIGDQILRINGFRLDDAVHKE----FIQLVAGQDRVTLKVRGVGML-------- 157

  Fly   394 FGPPSRDPMYASMAPPLHPQNQAAAAAAAAAASGAGLPFRQTCSWM-----DRHGRPASPPMEYG 453
               |.||                             || .:..||.     ...|.|:....: |
  Fly   158 ---PVRD-----------------------------LP-EERLSWSVVKLPSVSGTPSESSFK-G 188

  Fly   454 GRRSERRDRIRRVELLIEPGQSLGLMIRGGVEYGLGIFVTGVDKDSVADRSGLMIGDEILEVNGQ 518
            .||...||  ..|.|.:.|...|||.|..|.|:..||||......|||..:||..||:||.||..
  Fly   189 ERRGASRD--ISVVLHVAPRTKLGLGICKGPEWKPGIFVQFTKDRSVAREAGLRPGDQILSVNSI 251

  Fly   519 SFLDVTHDEAVGQLKYHKRMSLVIRDVGKVPHSCTSIEMEPWD-------AYSPTGTR----ARR 572
            .|.||...|||..:|...::.:|:|       :....::.|.:       |.|.||.:    |..
  Fly   252 DFSDVLFSEAVAVMKSSSKLDMVVR-------TAAGCDLFPGESSGYNSSASSVTGDQSPCWADA 309

  Fly   573 KGQIATMVEEKA--------RSLLPRHHFASLSYYIAEYSAKAMTIDAFVAVLLEMLDTYEKHTL 629
            |.:..|.|.|::        .|..|              .|.:......|.|..:|..|..|.|
  Fly   310 KSKRLTAVREESGAGGGGCGLSSAP--------------GAGSPNWSQGVEVHKQMNKTIIKLT- 359

  Fly   630 VTEIRELVFPEDRTRYDELVYRRERDPYSVDRHRRKGDPARDLPVTADDLEIIAATGRSPSSDSG 694
                      |:.|..:.                                ..||:||.|..|.||
  Fly   360 ----------ENGTSINN--------------------------------TYIASTGGSSVSGSG 382

  Fly   695 LGMTVTDIYKRPALQLPHRPMSAGPILHRSQPASHYQTGSNQSSSSLSPPQQQQ--QQQQHYQPH 757
                                 |.|         |.....|.||.|:.|.|.:..  .::.|.:|.
  Fly   383 ---------------------STG---------SGTSGRSQQSQSNPSNPSRNSTTMKRSHLRPV 417

  Fly   758 HASLRHLG---------GIGGNVGSGRHHHHPLGPSQLKFRQTKDNQQQEYGCDEHRTRRGSETL 813
            :::...:|         |..|:.|||......:.|:
  Fly   418 NSAGSGIGLSSGSAGSAGSAGSSGSGSRSGGVIAPA----------------------------- 453

  Fly   814 LPEYEPDAEQE-----------LATKLSRSFDMKEEGGTLLGDKGVRRHQSMQRLSAEQNG-GST 866
             |...|.|..|           |::.::.....::|      .:..::||.......:::| |:.
  Fly   454 -PAPPPPAMNEGANASGSVGSSLSSAITEELKKRKE------KQQQQQHQQRHNRDRDRDGNGNV 511

  Fly   867 TEQTHEHNPNVVPDHRGNL-HITVKKTKPILGIA--IEGGANTKHPLPRIINIHENGAAFEAGGL 928
            ..|...||.|  ..||.:: .::.::...:.|:|  ::|.       .||.|:...|.|..|||.
  Fly   512 DRQLTGHNGN--GGHRSSVGQVSHRQRANVAGVAATLQGS-------ERISNLTGGGGAGGAGGS 567

  Fly   929 EVGQLILEVDGTKVEGLHHQEVARLIAECFANREKAEITFLVVEAKKSNLEPKPTALIFLEAXHL 993
            .        ......|..|                   |.|:.|.|:::.......  |.|:.|.
  Fly   568 N--------GAAGAGGDQH-------------------TALMDEFKRAHQRMFRNG--FHESEHK 603

  Fly   994 LALPASDPLERQKLEFLYEWGIDLT------------ETPKPMPTPIPLTKA------------- 1033
            |:......|..:.|     :|.:::            |....|||..|::..
  Fly   604 LSSLGKSSLADRSL-----YGREMSLLRVKNGGSGGGEGSGVMPTMRPVSMGRPLVTMSTYQERG 663

  Fly  1034 ---KNPPPLPHEL-------------------------HNNINSQYGSSAALSNHQPHQHTHP-- 1068
               |....:|.|.                         :|.:.||.|.:.|..|..|.....|
  Fly   664 ETLKRTSIMPDESCYRNSINSNNNNGFSRNRSNSNTNNNNRLQSQNGVNPANGNGSPELPPPPPQ 728

  Fly  1069 --HPQQQQQQQQHSNTKTPNTNSNKTQGTPTTGTGAAT---TGS----KQQQQPGNTTNTPTKAS 1124
              :||.:|...||....|.|..:|        |:|:|.   .||    :|...|..:.:......
  Fly   729 FANPQPKQMPPQHIKPMTGNAAAN--------GSGSANGLGNGSLAKVRQPMSPMRSASISVGGF 785

  Fly  1125 R-EATPTREQHHQHATPTREHQQQTPTRQQQLQREQQQQ 1162
            | .|||   |....|...|..|.......:.:...|||:
  Fly   786 RPPATP---QPDYDAVQIRSSQGSESVSGRDVATSQQQR 821

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dysc	NP_001261810.1	PDZ_canonical	296..380	CDD:467153	21/83 (25%)
		PDZ2_FL-whirlin	466..546	CDD:467223	33/79 (42%)
		HN_L-whirlin_R2_like	573..653	CDD:259823	15/87 (17%)
		PDZ3_FL-whirlin-like	884..974	CDD:467224	16/92 (17%)
CG5921	NP_727061.2	PDZ1_harmonin	72..155	CDD:467219	26/100 (26%)
		PDZ_canonical	195..276	CDD:483948	34/82 (41%)