Protein Alignment dysc and Stxbp4

DIOPT Version :9

• Sequence 1: NP_001261810.1
• Gene: dysc / 39533
• FlyBaseID: FBgn0264006
• Length: 1254
• Species: Drosophila melanogaster
• Sequence 2: XP_006247190.1
• Gene: Stxbp4 / 303443
• RGDID: 1307903
• Length: 557
• Species: Rattus norvegicus
• Alignment Length: 455
• Identity: 98/455 - (21%)
• Similarity: 153/455 - (33%)
• Gaps: 147/455 - (32%)

  Fly   259 GRRSPASSPPSTTHQIYRDRERERDRSVPNIHELTTRTVSMSRDQQIDHGFGICVKGGKDSGLG- 322
            |..|..||.|           .|||.:.        |.::::::.    |.|:.:.||.|...|
  Rat     4 GTSSARSSSP-----------LERDPAF--------RVITVAKET----GLGLKILGGIDRNEGP 45

  Fly   323 -VYISRIEENSVAERAG-LRPGDTILEVNGTPFTSINHEEA---LKRCVQILKSSRQI------- 375
             |||..:.......:.| |:|||.::.:|......::.|||   |.|.....:|..:|
  Rat    46 LVYIHEVTPGGDCYKDGRLKPGDQLVSINKESMIGVSFEEAKNILTRAKLRWESPLEIAFIRQKS 110

  Fly   376 ------SMTVRAPPT-------------LNSTA----PLHGFGPPSRDPMYAS----MAPPLHPQ 413
                  ::..::||.             |:|.|    |.....|.::|.:..|    ...|.|.|
  Rat   111 YCGHPGNICCQSPPVSEDCEPQTSAFNLLSSPAGTLLPKTSSTPRTQDSILPSCTVIQTQPEHSQ 175

  Fly   414 NQAAAAAAAAAASGAGLPFRQT--------CSWMDRHGRPASPPMEYGGRRSERRDRIRRVELLI 470
                    |..|....|..|.|        .:|.|    .||.|..........|.:..::|:.:
  Rat   176 --------AGLAPVPSLNNRPTDTSNADIAPAWTD----DASGPQGKISLNPSARLKAEKLEMAL 228

  Fly   471 ---------EPGQSLGLMIR----GGVEYG------LGIFVTGVDKDSVADRSGLMIGDEILEVN 516
                     |..::|...::    |.|.:|      ..:|...:|:.:|.|.       |:..|.
  Rat   229 NYLGIQPTKEQHEALRQQVQADSEGTVSFGDFVQVARNLFCLQLDEVNVGDH-------ELPSVL 286

  Fly   517 GQSFLDVTHDEA--VGQLKYHKRMSLVIRDVGK------VPHSCTSIEMEPWDAYSPTGTRARRK 573
            ....|.....||  ||:|:..:..:|..||..|      ..|....||            ..:..
  Rat   287 DSQLLPCGSLEADEVGRLRQERNAALEERDALKEKLLESEKHRKQLIE------------ELQNV 339

  Fly   574 GQIATMVEEKARSLLPRHHFASLSYYIAEYSAKAMTIDAFVAVLLEMLDTYEK--HTLVTEIREL 636
            .|.|..|.|:.|:|..|.|.|.    .|:..|:.|.:|            ||:  ..|..|:.||
  Rat   340 KQEAKAVAEETRALRSRIHLAE----AAQRQARGMEMD------------YEEVIRLLEAEVSEL 388

  Fly   637  636
              Rat   389  388

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dysc	NP_001261810.1	PDZ_signaling	294..380	CDD:238492	23/104 (22%)
		PDZ_signaling	466..543	CDD:238492	19/97 (20%)
		HN_L-whirlin_R2_like	573..653	CDD:259823	19/66 (29%)
		PDZ_signaling	886..971	CDD:238492
Stxbp4	XP_006247190.1	PDZ_signaling	21..94	CDD:238492	21/76 (28%)
		TPR_MLP1_2	299..400	CDD:285204	29/118 (25%)
		GBP_C	<306..389	CDD:303769	26/111 (23%)
		coiled coil	359..369	CDD:293879	3/13 (23%)
		coiled coil	378..389	CDD:293879	4/11 (36%)
		WW	502..531	CDD:278809

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900