DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dysc and F20D6.1

DIOPT Version :9

Sequence 1:	NP_001261810.1	Gene:	dysc / 39533	FlyBaseID:	FBgn0264006	Length:	1254	Species:	Drosophila melanogaster
Sequence 2:	NP_505110.2	Gene:	F20D6.1 / 184722	WormBaseID:	WBGene00017633	Length:	180	Species:	Caenorhabditis elegans

Alignment Length:	202	Identity:	40/202 - (19%)
Similarity:	66/202 - (32%)	Gaps:	78/202 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly   465 RVELLIEPGQSLGLMIRGGVEYGLGIFVTGVDKD-SVADRSGLMIGDEILEVNGQSFLDVTHDEA 528
            ::.|:..|...||:.::   .|...::|...|.. ....|..|.:||.||.::....||:
Worm     4 KLVLIYFPRSKLGINVK---SYQNVVYVESTDNTWGSTTRRFLYLGDAILRIDDTEILDL----- 60

  Fly   529 VGQLKYHKRMSLVIRDVGKVPHSCTSIEMEPWDAYSPTGTRARR----KGQIATMVEEKA----- 584
                                                ||...|.|    |..:.|::.|:|
Worm    61 ------------------------------------PTTQNALRTGFSKNGVVTIIVERAVHQES 89

  Fly   585 ----RS----------LLPRHHF----ASLSYY----IAEYSA--KAMTIDAFVAVLLEMLDTYE 625
                ||          :||:...    |.|:|:    .||.:.  |..|.|...|..:.:.:|.|
Worm    90 YAFVRSVMGFSKVLDPMLPQDVIQTCTARLAYHNKHGFAEPTPIFKGYTKDYSSAGRVSVTNTVE 154

  Fly   626 KHTLVTE 632
            ..::.||
Worm   155 IKSIRTE 161

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dysc	NP_001261810.1	PDZ_signaling	294..380	CDD:238492
		PDZ_signaling	466..543	CDD:238492	15/77 (19%)
		HN_L-whirlin_R2_like	573..653	CDD:259823	21/89 (24%)
		PDZ_signaling	886..971	CDD:238492
F20D6.1	NP_505110.2	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900