Protein Alignment dysc and Lnx2

DIOPT Version :9

• Sequence 1: NP_001261810.1
• Gene: dysc / 39533
• FlyBaseID: FBgn0264006
• Length: 1254
• Species: Drosophila melanogaster
• Sequence 2: NP_542985.4
• Gene: Lnx2 / 140887
• MGIID: 2155959
• Length: 687
• Species: Mus musculus
• Alignment Length: 462
• Identity: 103/462 - (22%)
• Similarity: 163/462 - (35%)
• Gaps: 144/462 - (31%)

  Fly   196 GTLPTSTAASGRSMGQHASSNGNKKRPISPEQVLRMFGATQSSSVPTSSYHYSNGGTRDRDRTGR 260
            ||||..|..||...|:         |.::|            :|:|..:           :..|.
Mouse   173 GTLPPETDCSGTVPGE---------RNLTP------------ASLPVWT-----------EEPGL 205

  Fly   261 RSPASSPPSTTHQIYRDRERERDRSVPNIHELTTRTVSMSRDQ-QIDHGFGICVKGGKDSGL-GV 323
            .:||....:....:      ::..|:|. .|:||..:..|... |:    ||.:.||.::.| .:
Mouse   206 DNPAFEESAAADSV------QQPLSLPE-GEITTIEIHRSNPYIQL----GISIVGGNETPLINI 259

  Fly   324 YISRIEENSVAERAG-LRPGDTILEVNGTPFTSINHEEALKRCVQILKSSRQISMTVRAPPTLNS 387
            .|..:..:.|..|.| |..||.||:||....::::|..|  |.| :.:....:.:||.......|
Mouse   260 VIQEVYRDGVIARDGRLLAGDQILQVNNYDISNVSHNHA--RAV-LSQPCSTLQLTVLRERRFGS 321

  Fly   388 TAPLHGFGPPSRDPMY------------------------------------ASMAPPLHPQNQA 416
            .|..|..|...||.::                                    |:....|:..::.
Mouse   322 RANSHADGSAPRDEVFQVLLHKRDSTEQLGIKLVRRTDEPGVFILDLLEGGLAAQDGRLNSNDRV 386

  Fly   417 AA-------------AAAAAAASGAGLPFRQTCSWMDRHGRP-----------------ASPPME 451
            .|             ||....|||..:...     :.|.|:|                 |.||..
Mouse   387 LAINGHDLKHGTPELAAQIIQASGERVNLT-----IARPGKPQPSNGSREAGAHSSSNHAQPPSH 446

  Fly   452 YGGRRSERRDRIR-------RVELLIEPGQSLGLMIRG--GVEYG-LGIFVTGVDKDSVADRSG- 505
              .|....:|..|       .:.:..||.:|||:.:.|  |.:.| |.||||.|.......|.|
Mouse   447 --SRPGSHKDLTRCVTCQEKHITVKKEPHESLGMTVAGGRGSKSGELPIFVTSVPPHGCLARDGR 509

  Fly   506 LMIGDEILEVNGQSFLDVTHDEAVGQLKYHKRMSLVI---RDVGKVPHSCTSIEMEP-------W 560
            :..||.:|.:||....:::|.|||..||.......||   .:|.....:..:.|.:|       :
Mouse   510 IKRGDVLLNINGIDLTNLSHSEAVAMLKASAASPAVILKALEVQIAEEAAQATEEQPSAFSENEY 574

  Fly   561 DA-YSPT 566
            || :||:
Mouse   575 DASWSPS 581

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dysc	NP_001261810.1	PDZ_signaling	294..380	CDD:238492	24/88 (27%)
		PDZ_signaling	466..543	CDD:238492	29/83 (35%)
		HN_L-whirlin_R2_like	573..653	CDD:259823
		PDZ_signaling	886..971	CDD:238492
Lnx2	NP_542985.4	mRING-HC-C3HC3D_LNX2	46..90	CDD:319694
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	145..175		1/1 (100%)
		NPXY motif	207..210		1/2 (50%)
		PDZ	229..315	CDD:214570	27/92 (29%)
		PDZ_signaling	336..418	CDD:238492	8/86 (9%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	417..454		7/38 (18%)
		PDZ_signaling	463..539	CDD:238492	27/75 (36%)
		PDZ_signaling	596..680	CDD:238492

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900