DRSC/TRiP Functional Genomics Resources

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Protein Alignment dysc and Slc9a3r2

DIOPT Version :9

Sequence 1:NP_001261810.1 Gene:dysc / 39533 FlyBaseID:FBgn0264006 Length:1254 Species:Drosophila melanogaster
Sequence 2:NP_446263.2 Gene:Slc9a3r2 / 116501 RGDID:620380 Length:337 Species:Rattus norvegicus


Alignment Length:364 Identity:84/364 - (23%)
Similarity:130/364 - (35%) Gaps:119/364 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   292 LTTRTVSMSRDQQIDHGFGICVKGGKDSGLGVYISRIEENSVAERAGLRPGDTILEVNGTPFTSI 356
            |..|...:.|.:|   |:|..:.|.| ...|.:|.|:|..|.||.|.||.||.::||||......
  Rat     7 LRPRLCRLVRGEQ---GYGFHLHGEK-GRRGQFIRRVEPGSPAEAAALRAGDRLVEVNGVNVEGE 67

  Fly   357 NHEEALKRCVQILKSSRQISMTVRAPP------TLNSTAPL-HGFGPPSRDPMYASMAPPLHPQN 414
            .|.:.::| ::.::...|:.:..:...      .|..|..: |...||:.:|.        .|:.
  Rat    68 THHQVVQR-IKAVEGQTQLLVVDKETDEELCRRQLTCTEEMAHRGLPPAHNPW--------EPKP 123

  Fly   415 QAAAAAAAAAASGAGLPFRQTCSWMDRHGRPASPPMEYGGRRSERRDRIRRVELLIEPGQSLGLM 479
            ..|.:.:..:.:|.          .|.:|    ||.|...|....|                   
  Rat   124 DWACSGSLGSDTGQ----------KDVNG----PPRELRPRLCHLR------------------- 155

  Fly   480 IRGGVEYGL---------GIFVTGVDKDSVADRSGLMIGDEILEVNGQSFLDVTHDEAVGQLK-- 533
             ||...||.         |.::..||..|.|..|||...|.::|||||:...:.|.|.|.::|  
  Rat   156 -RGPQGYGFNLHSDKSRPGQYIRSVDPGSPASLSGLRAQDRLIEVNGQNVEGLRHAEVVARIKAQ 219

  Fly   534 ---------------YHKRMSLVIRD---VGKVPHS---------------CTSIEMEP------ 559
                           :.||:.:|..:   .|.:|..               |:|....|      
  Rat   220 EDEARLLVVDPETDEHFKRLRVVPTEDHVEGPLPSPVTNGTSLAQLNGGSVCSSRSDLPGSEKDN 284

  Fly   560 -----W--DAY-------SPTGTRARRKGQIATMVEEKA 584
                 |  |.:       |||...|:.|.: ||.|.::|
  Rat   285 EDGSAWKRDPFQESGLHLSPTAAEAKEKAR-ATRVNKRA 322

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dyscNP_001261810.1 PDZ_signaling 294..380 CDD:238492 26/85 (31%)
PDZ_signaling 466..543 CDD:238492 25/102 (25%)
HN_L-whirlin_R2_like 573..653 CDD:259823 5/12 (42%)
PDZ_signaling 886..971 CDD:238492
Slc9a3r2NP_446263.2 PDZ_signaling 9..88 CDD:238492 26/83 (31%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 127..146 5/32 (16%)
PDZ_signaling 149..228 CDD:238492 24/98 (24%)
EBP50_C 232..337 CDD:401087 19/92 (21%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 246..337 16/78 (21%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3528
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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