DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8745 and phykpl

DIOPT Version :9

Sequence 1:	NP_648665.1	Gene:	CG8745 / 39530	FlyBaseID:	FBgn0036381	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	NP_001032646.1	Gene:	phykpl / 557205	ZFINID:	ZDB-GENE-051127-33	Length:	447	Species:	Danio rerio

Alignment Length:	445	Identity:	230/445 - (51%)
Similarity:	319/445 - (71%)	Gaps:	12/445 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 VASEQLSKTETIKLRNQHIGQACQLFYRSDPLKIVRGQGQYMFDEEGTRYLDCINNVAHVGHCHP 75
            :|.|...|.||:::|.:.|.|:|:||:..||:||||.:|||::||.||:|||||:||.||||.||
Zfish     1 MAVELFHKNETLQMRKKLIAQSCRLFFSHDPVKIVRARGQYLYDENGTQYLDCISNVQHVGHSHP 65

  Fly    76 EVVRAGALQMATISTNNRFLHDELVQCARTLTSKMPEPLSVCFFVNSGSEANDLALRLARNFTKR 140
            .:.:....||..::||.|||||.:||.|..|.:.:|:.|||.:|||||||||||||||||.:|:.
Zfish    66 SITQVAGAQMDLLNTNTRFLHDNIVQYADRLAATLPKKLSVFYFVNSGSEANDLALRLARQYTRH 130

  Fly   141 QDVITLDHAYHGHLQSVMEVSPYKFNQPGGEAKPDYVHVAPCPDVYGGKFTDKMYPDADMGALYA 205
            ||||.|||||||||.|::::|||||.:.  |.:.::|||||.||.|.|.:.:. :|:.  |..||
Zfish   131 QDVIVLDHAYHGHLTSLIDISPYKFRKL--EGQKEWVHVAPLPDTYHGIYRED-HPEP--GQAYA 190

  Fly   206 QPIEEICQKQLAKGQGVAAFIAESLQSCGGQILPPAGYFQAVYDAVRSAGGVCIADEVQVGFGRV 270
            ..::.:.::...||:.:::|.||||.|.||||:.|.||.:.|.:.|..||||.:|||:|.|||||
Zfish   191 DTVKSLIEEAHKKGRKISSFFAESLPSVGGQIIFPTGYCKRVAEYVHEAGGVYVADEIQTGFGRV 255

  Fly   271 GSHYWAF--ETQNVIPDIVCVAKPMGNGHPVGAVVTTPEIAQAFHATGVAYFNTYGGNPVSCAIA 333
            |||:|||  |.::..||||.:.||||||||:..||||.|||.||.|.||.||||:|||||||||.
Zfish   256 GSHFWAFQLEGEDFCPDIVTMGKPMGNGHPIACVVTTEEIAGAFTANGVEYFNTFGGNPVSCAIG 320

  Fly   334 NAVMRVIEEEGLQQKALVLGDYLLEECNRLKQEFECIGDVRGAGLFVGIELVQDRKERIPDKKAA 398
            .||:.|||:|.|:..|:.:|.:|.:...:|:::...||||||.|||:|:|||:||:.|.|..:.|
Zfish   321 LAVLDVIEKEDLRGNAVRVGGHLKQLLLQLQEKHLLIGDVRGVGLFIGMELVKDRESREPATEEA 385

  Fly   399 HWVVNRMKQLHRVLVSSDGPNDNVIKLKPPMCFNRENADEFLLGFRECLTAVMQE 453
            ..:|.|:|: .|:::|:|||.|:|||.||||||::|:|:..:    .|:..::.|
Zfish   386 AHLVRRLKE-DRIVMSTDGPWDSVIKFKPPMCFSKEDANRVV----TCIDQILTE 435

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8745	NP_648665.1	GabT	20..450	CDD:223238	226/431 (52%)
CG8745	NP_648665.1	OAT_like	37..447	CDD:99735	217/411 (53%)
phykpl	NP_001032646.1	GabT	10..437	CDD:223238	227/436 (52%)
phykpl	NP_001032646.1	OAT_like	29..433	CDD:99735	218/413 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	467	1.000	Domainoid score	I442
eggNOG	1	0.900	-	-		E1_COG0160
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	502	1.000	Inparanoid score	I1323
OMA	1	1.010	-	-		QHG63788
OrthoDB	1	1.010	-	-		D145181at2759
OrthoFinder	1	1.000	-	-		FOG0000701
OrthoInspector	1	1.000	-	-		otm24360
orthoMCL	1	0.900	-	-		OOG6_103965
Panther	1	1.100	-	-	O	PTHR45688
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1960
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.840