DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8745 and Gabat

DIOPT Version :9

Sequence 1:	NP_648665.1	Gene:	CG8745 / 39530	FlyBaseID:	FBgn0036381	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	NP_001163479.1	Gene:	Gabat / 40188	FlyBaseID:	FBgn0036927	Length:	486	Species:	Drosophila melanogaster

Alignment Length:	507	Identity:	111/507 - (21%)
Similarity:	193/507 - (38%)	Gaps:	110/507 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 NLVASEQLSKT------ETIKLRNQ--HIGQACQLFYRSDPLKIVRGQGQYMFDEEGTRYLDCIN 65
            |:...|.:.||      ::|:|:.|  .:.....:.:.:|..|.:   |.|::|.:|...||...
  Fly    25 NVEPKEPVVKTKSIPGPKSIELKKQLDSVQATGTIQFFADYEKSI---GNYIYDVDGNILLDVYT 86

  Fly    66 NVAHV--GHCHPEVVRAGALQMATISTNNR-------------FLHDELVQCARTLTSKMPEPLS 115
            .::.|  |:.||.:.:....:....:..||             .||..|:..|       |:.|:
  Fly    87 QISSVPLGYNHPRLYKVFNNEQNLKTLINRPALGVFPGKEWPEKLHSVLLNIA-------PKGLN 144

  Fly   116 VCFFVNSGSEANDLA-----------LRLARNFTKRQ---------------DVITLDHAYHGHL 154
            ....:..||.:|:.|           ||.....|:::               .:::...|:||..
  Fly   145 KITTMMCGSCSNENAYKSIFIWYQNKLRGNAPLTEQEKNSCMINIPPGAPKLSILSFKGAFHGRT 209

  Fly   155 QSVMEVSPYKFNQPGGEAKPDYVHVAPCP--DVYGGKFTDKMYPDADMGALYAQPIEEICQ---- 213
            ...:..:..|           |:|....|  |.....|.:..|| .|....:.:..:|.|.
  Fly   210 LGALSTTHSK-----------YIHKLDVPSFDWPIASFPEYRYP-LDENVAHNKKEDEKCLSEVQ 262

  Fly   214 ---KQLAKGQGVAAFIAESLQSCGGQILPPAGYFQAVYDAVRSAGGVCIADEVQVGFGRVGSHYW 275
               :|.|....||..:.|.:||.||.......:|:::....:..|...:.||||.|.|..|. :|
  Fly   263 DLIQQYASKNPVAGIVVEPIQSEGGDNEASPEFFRSLQAICKKNGIALLIDEVQTGGGSTGK-FW 326

  Fly   276 A---FETQNVIPDIVCVAKPM---GNGHPVGAVVTTPEIAQAFHATGVAYFNTYGGNPVSCAIAN 334
            |   ||.::. ||:|..:|.:   |..|....:...|          ...|||:.|:|....:..
  Fly   327 AHEHFELESP-PDVVTFSKKLQLGGYFHNDDFIPNEP----------YRIFNTWMGDPGKVLLLE 380

  Fly   335 AVMRVIEEEGLQQKALVLGDYLLEECNRLKQEF-ECIGDVRGAGLFVGIELVQDRKERIPDKKAA 398
            .|::||:||.|.....|.|..|......|::|| ..:...||.|.|:.:...        :.|..
  Fly   381 EVVKVIQEEKLLANVDVAGKVLKNGLLSLEKEFPHILNSTRGRGTFLAVNCT--------NTKVR 437

  Fly   399 HWVVNRMKQLHRVLVSSDGPNDNVIKLKPPMCFNRENADEFLLGFRECLTAV 450
            ..::..:| ||.  :.:.|..:..|:.:|.:.|...:|:..|..||:.|..:
  Fly   438 DQIIGALK-LHG--IQTGGCGEISIRFRPALIFKEYHANIVLDRFRKVLQGI 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8745	NP_648665.1	GabT	20..450	CDD:223238	107/488 (22%)
CG8745	NP_648665.1	OAT_like	37..447	CDD:99735	103/466 (22%)
Gabat	NP_001163479.1	GabT	27..484	CDD:223238	109/501 (22%)
Gabat	NP_001163479.1	AAT_I	27..483	CDD:302748	109/500 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439933
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0160
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740