DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8745 and SPBC1773.03c

DIOPT Version :9

Sequence 1:	NP_648665.1	Gene:	CG8745 / 39530	FlyBaseID:	FBgn0036381	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	NP_595118.1	Gene:	SPBC1773.03c / 2539964	PomBaseID:	SPBC1773.03c	Length:	459	Species:	Schizosaccharomyces pombe

Alignment Length:	482	Identity:	137/482 - (28%)
Similarity:	224/482 - (46%)	Gaps:	71/482 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 SEQLSKTETIKLRNQHIGQACQLFYRSD---PLKIVRGQGQYMFDEEGTRYLDCINN--VAHVGH 72
            :|.::.|.:.|...::     .|||.|.   |..:||.:|.|::.|:|||.:|....  ||.:||
pombe     2 TETVTTTSSDKSEKKN-----YLFYTSPNHRPPTVVRAEGVYLYLEDGTRIMDATGGAAVACLGH 61

  Fly    73 CHPEVVRAGALQMATISTNNRFLH---------DELVQCARTLTSKMPEPLSVCFFVNSGSEAND 128
            .:.||:.|...|...:.    ::|         |:|   |..|.|:.|:..:..:|.||||||.:
pombe    62 GNKEVIDAMHKQSEKVC----YIHSMGFSNEPADKL---ANLLVSEHPDVFARAYFANSGSEAVE 119

  Fly   129 LALRLARNF------TKRQDVITLDHAYHGHLQSVMEV-------SPYKFNQPGGEAKPDYVHVA 180
            ..|:|...:      .:|..:|.....|||:....:.|       .||:     |.......||:
pombe   120 TCLKLILQYWQLVGEKQRCHIIARKQGYHGNTLFALSVGGMKPRKQPYE-----GVFSHTTSHVS 179

  Fly   181 PCPDV---YGGKFTDKMYPDADMGALYAQPIEEICQKQLAKG-QGVAAFIAESLQ-SCGGQILPP 240
            ||.:.   ..|:.|::         ..|:..:|:..:.|..| :.||||:||::. :|.|...|.
pombe   180 PCFEYRYKENGETTEE---------YVARLAKELEDEILRVGPEKVAAFVAETVSGACTGCATPV 235

  Fly   241 AGYFQAVYDAVRSAGGVCIADEVQVGFGRVGS-HYWAFETQNVIPDIVCVAKPMGNGH-PVGAVV 303
            .|||:|:.......|.:...|||..|.||.|: |.|  |.:.|.|||..:||.:|.|: |:...:
pombe   236 PGYFKAMRKVCDKYGVIFYLDEVMSGIGRTGTMHAW--EQEGVTPDIQSIAKCLGGGYQPISGAL 298

  Fly   304 TTPEIAQAFHA--TGVAYFNTYGGNPVSCAIANAVMRVIEEEGLQQKALVLGDYLLEECNRLKQE 366
            ....|...|..  ..:|.|.||..:|::|:.|.||..::..:.|.::|..:|.||.|:.:.....
pombe   299 VGHRIMNVFEQKDAAMAGFFTYQAHPIACSAALAVQTILRRDHLVERAAEMGKYLSEKLHETFDS 363

  Fly   367 FECIGDVRGAGLFVGIELVQDR--KERIPDKKAAHWVVNRMKQLHRVLV-----SSDGPNDNVIK 424
            ...:|::||.|||.|:|:|:|:  ||..|.:.....:.|::...|.|.|     :.||...:.:.
pombe   364 HPNVGNIRGRGLFWGLEIVKDKATKECFPPEYKVGSLANKIGCEHGVFVYPGMGTIDGTRGDHVL 428

  Fly   425 LKPPMCFNRENADEFLLGFRECLTAVM 451
            |.||....||..||.:....:.:|:.:
pombe   429 LAPPYIITREQIDELVEALSKTITSTV 455

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8745	NP_648665.1	GabT	20..450	CDD:223238	135/472 (29%)
CG8745	NP_648665.1	OAT_like	37..447	CDD:99735	131/452 (29%)
SPBC1773.03c	NP_595118.1	AAT_I	18..459	CDD:302748	134/461 (29%)
SPBC1773.03c	NP_595118.1	GabT	28..452	CDD:223238	129/446 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	158	1.000	Domainoid score	I1020
eggNOG	1	0.900	-	-		E1_COG0160
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	163	1.000	Inparanoid score	I1230
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000701
OrthoInspector	1	1.000	-	-		otm47079
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2389
SonicParanoid	1	1.000	-	-		X1960
TreeFam	0	0.000	Not matched by this tool.
	9	8.890