Protein Alignment CG8745 and ABAT

DIOPT Version :10

• Sequence 1: NP_648665.1
• Gene: CG8745 / 39530
• FlyBaseID: FBgn0036381
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_001373544.1
• Gene: ABAT / 18
• HGNCID: 23
• Length: 532
• Species: Homo sapiens
• Alignment Length: 533
• Identity: 112/533 - (21%)
• Similarity: 192/533 - (36%)
• Gaps: 150/533 - (28%)

  Fly    16 LSKTETIKLRNQHIGQACQLFYRSDPLKIV----RGQGQYMFDEEGTRYLDCINNVAHV------ 70
            |.|||....|:|.:.:...:...::.:...    ..:|.|:.|.:|.|.||..:.::.|
Human    45 LMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIEMVV 109

  Fly    71 ----------------------------GHCHPEVVR-AGALQMATISTNNRFL----HDELVQC 102
                                        |:.||.::: ....|.|::..|...|    .:..|:.
Human   110 SLCAAQAGLELLDSSDPPTLASQSARISGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEK 174

  Fly   103 AR-TLTSKMPEPLSVCFFVNSGSEANDLAL-----------RLARNFTKRQ-------------- 141
            .| :|.|..|:.:|....:..||.:|:.||           |..|.|::.:
Human   175 LRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPD 239

  Fly   142 -DVITLDHAYHG---------HLQSVMEVSPYKFNQPGGEAKPDYVHVAPCPDVYGGKFTDKMYP 196
             .:::...|:||         |.:::.::....|:.|          :||.|.:        .||
Human   240 YSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWP----------IAPFPRL--------KYP 286

  Fly   197 -------DADMGALYAQPIEEICQKQLAKGQGVAAFIAESLQSCGGQILPPAGYFQAVYDAVRSA 254
                   :....|...:.:|::..|...|.:.||..|.|.:||.||.......:|:.:.|..|..
Human   287 LEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKH 351

  Fly   255 GGVCIADEVQVGFGRVGSHYWAFETQNV--IPDIVCVAKPMGNGHPVGAVVTTPEIAQAFH---- 313
            |...:.||||.|.|..|. :||.|...:  ..|::..:|.|..|             ..||
Human   352 GCAFLVDEVQTGGGCTGK-FWAHEHWGLDDPADVMTFSKKMMTG-------------GFFHKEEF 402

  Fly   314 ATGVAY--FNTYGGNPVSCAIANAVMRVIEEEGLQQKALVLGDYLLEECNRLKQEF-ECIGDVRG 375
            .....|  |||:.|:|....:...|:.:|:.|.|...|...|..||.....|:..: :.|..|||
Human   403 RPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRG 467

  Fly   376 AGLFVGIELVQDRKERIPDKKAAHWVVNRMKQLHRVLVSSD------GPNDNVIKLKPPMCFNRE 434
            .|.|...:...|.            :.|::     :|::.:      |..|..|:.:|.:.|...
Human   468 RGTFCSFDTPDDS------------IRNKL-----ILIARNKGVVLGGCGDKSIRFRPTLVFRDH 515

  Fly   435 NADEFLLGFRECL 447
            :|..||..|.:.|
Human   516 HAHLFLNIFSDIL 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8745	NP_648665.1	PRK06148	<11..450	CDD:180426	112/533 (21%)
ABAT	NP_001373544.1	GABAtrns_euk	34..528	CDD:129782	111/531 (21%)