DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8745 and agxt2

DIOPT Version :9

Sequence 1:	NP_648665.1	Gene:	CG8745 / 39530	FlyBaseID:	FBgn0036381	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	XP_002940002.3	Gene:	agxt2 / 100491739	XenbaseID:	XB-GENE-993827	Length:	508	Species:	Xenopus tropicalis

Alignment Length:	486	Identity:	188/486 - (38%)
Similarity:	263/486 - (54%)	Gaps:	55/486 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 VASEQLSKTE---------------------TIKLRNQHIGQACQLFYRSDPLKIVRGQGQYMFD 54
            |:|...||.|                     .:::|.|.|..:....|:. ||.:.:|..|::||
Frog    30 VSSRHFSKDEHPVMPPCDFEPVKYESDPFERILEIRKQRIAPSLYTIYKK-PLLLHQGHKQWLFD 93

  Fly    55 EEGTRYLDCINNV--AHVGHCHPEVVRAGALQMATI-STNNRFLHDELVQCARTLTSKMPEPLSV 116
            .||.||||.|..:  ..||||||::..|...|...: .|:|.||:..:.:.|..||..:|..|.|
Frog    94 NEGRRYLDLIAGIVTVSVGHCHPKITEAAHKQFGRLCHTSNIFLNPPIHEYAEKLTDLLPGKLKV 158

  Fly   117 CFFVNSGSEANDLALRLARNFTKRQDVITLDHAYHGH---LQSVMEVSPYKFNQPGGEAKPDYVH 178
            .:|.|||:|||:||:::||.:|...|:|:|...|||.   ..||..|:.||    .|.|.....:
Frog   159 VYFTNSGTEANELAMQMARVYTGNCDIISLRGGYHGSGPTAVSVTAVASYK----PGVATSSNCY 219

  Fly   179 VAPCPDVYGGKFTDKMYPDADMGAL---------------YAQPIEE-ICQKQLAKGQGVAAFIA 227
            ...||||:.|.:......|:.:..:               |....:| :|   .:.||.||||||
Frog   220 TTMCPDVFHGIWGGSHCRDSPVQTIRKCSCSPGCCEAKDQYIDQFKETLC---TSTGQRVAAFIA 281

  Fly   228 ESLQSCGGQILPPAGYFQAVYDAVRSAGGVCIADEVQVGFGRVGSHYWAFETQNVIPDIVCVAKP 292
            |.:|..||.:..|.|:.:..|:.||..||:|||||||.||||.|||||.|:|.:|:||||.:||.
Frog   282 EPIQGVGGAVQYPKGFLKEAYNLVRERGGLCIADEVQTGFGRTGSHYWGFQTHDVMPDIVTMAKG 346

  Fly   293 MGNGHPVGAVVTTPEIAQAFHATGVAYFNTYGGNPVSCAIANAVMRVIEEEGLQQKALVLGDYLL 357
            :|||.|:||||||.|||:.|  ....:|||:|||||:||:.:||:.||||||||:...|:|..:|
Frog   347 IGNGFPMGAVVTTQEIAKPF--ANFMHFNTFGGNPVACAVGSAVLDVIEEEGLQKNCEVIGTQML 409

  Fly   358 EECNRLKQEFECIGDVRGAGLFVGIELVQDRKERIP-DKKAAHWVVNRMKQLHRVLVSSDGPNDN 421
            .|..:|:..||.||||||.||.:|||:|:|::.|.| ..:..:.:....|.: .||....|....
Frog   410 LEFAKLRDMFEIIGDVRGKGLMIGIEMVKDKESRKPLAAQEMNLIWEDCKDM-GVLFGKGGIYGQ 473

  Fly   422 VIKLKPPMCFNRENADEFLLGFRECLTAVMQ 452
            ..::|||||...|:.......|...||..|:
Frog   474 TFRIKPPMCVTSEDVAFAADVFHRALTRHME 504

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8745	NP_648665.1	GabT	20..450	CDD:223238	183/473 (39%)
CG8745	NP_648665.1	OAT_like	37..447	CDD:99735	177/432 (41%)
agxt2	XP_002940002.3	OAT_like	74..499	CDD:99735	177/435 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG63788
OrthoDB	1	1.010	-	-		D145181at2759
OrthoFinder	1	1.000	-	-		FOG0000701
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.930