DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8745 and Phykpl

DIOPT Version :9

Sequence 1:	NP_648665.1	Gene:	CG8745 / 39530	FlyBaseID:	FBgn0036381	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	XP_038940910.1	Gene:	Phykpl / 100169747	RGDID:	2293818	Length:	503	Species:	Rattus norvegicus

Alignment Length:	471	Identity:	229/471 - (48%)
Similarity:	330/471 - (70%)	Gaps:	13/471 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 VASEQLSKTETIKLRNQHIGQACQLFYRSDPLKIVRGQGQYMFDEEGTRYLDCINNVAHVGHCHP 75
            :|:::.:|..|:.||.:.:..:|:||:..:|:||:||||||::||:|..||||||||||||||||
  Rat     1 MAADRRAKAATLDLRRRLLSSSCRLFFPENPVKIIRGQGQYLYDEQGREYLDCINNVAHVGHCHP 65

  Fly    76 EVVRAGALQMATISTNNRFLHDELVQCARTLTSKMPEPLSVCFFVNSGSEANDLALRLARNFTKR 140
            .||:|...|...::||:|:|||.:|..|:.|:..:||.|||.:|:|||||||||||||||.:|..
  Rat    66 TVVQAAHEQNLVLNTNSRYLHDNIVDYAQRLSETLPEKLSVFYFLNSGSEANDLALRLARQYTGH 130

  Fly   141 QDVITLDHAYHGHLQSVMEVSPYKFNQPGGEAKPDYVHVAPCPDVYGGKFTDKMYPDADMGALYA 205
            |||:.|||||||||.|::::|||||....|:  .::|||||.||.|.|.:.:. :|| ..|| ||
  Rat   131 QDVVVLDHAYHGHLSSLIDISPYKFRNLDGQ--KEWVHVAPLPDTYRGPYRED-HPD-PAGA-YA 190

  Fly   206 QPIEEICQKQLAKGQGVAAFIAESLQSCGGQILPPAGYFQAVYDAVRSAGGVCIADEVQVGFGRV 270
            ..::.:......||:.:|||.||||.|..|||:||||||..|.:.:|.|||:.:|||:|||||||
  Rat   191 SEVKHVISSAQKKGRKIAAFFAESLPSVSGQIIPPAGYFSQVAEHIRRAGGLFVADEIQVGFGRV 255

  Fly   271 GSHYWAF--ETQNVIPDIVCVAKPMGNGHPVGAVVTTPEIAQAFHATGVAYFNTYGGNPVSCAIA 333
            |.|:|||  |.::.:||||.:.|.:||||||..:.||..:::||.||||.||||:||||||||:.
  Rat   256 GKHFWAFQLEGEDFVPDIVTMGKSIGNGHPVACLATTQAVSRAFEATGVEYFNTFGGNPVSCAVG 320

  Fly   334 NAVMRVIEEEGLQQKALVLGDYLLEECNRLKQEFECIGDVRGAGLFVGIELVQDRKERIPDKKAA 398
            .||:.|::.|.||..|..:|.:|:|..::.|.:...||||||.|||:|::|::|...|.|..:.|
  Rat   321 LAVLDVLKTEQLQAHATNVGSFLMEHLSQQKAKHPIIGDVRGTGLFIGVDLIKDETLRTPATEEA 385

  Fly   399 HWVVNRMKQLHRVLVSSDGPNDNVIKLKPPMCFNRENADEFLLGFRECLTAVMQERLASATSAAM 463
            .::|:|:|: :.:|:|:|||..|::|.||||||:.:||...:....:.||. |:|::.|..:..:
  Rat   386 EYLVSRLKE-NYILLSTDGPGRNILKFKPPMCFSLDNAQHVVAKLDDILTD-MEEKVRSCETLRI 448

  Fly   464 AATSGV----IATATE 475
            ....|:    :.|||:
  Rat   449 KHPPGMCVPRLRTATK 464

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8745	NP_648665.1	GabT	20..450	CDD:223238	220/431 (51%)
CG8745	NP_648665.1	OAT_like	37..447	CDD:99735	212/411 (52%)
Phykpl	XP_038940910.1	PRK06148	<6..433	CDD:180426	219/432 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	483	1.000	Domainoid score	I385
eggNOG	1	0.900	-	-		E1_COG0160
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	518	1.000	Inparanoid score	I1233
OMA	1	1.010	-	-		QHG63788
OrthoDB	1	1.010	-	-		D145181at2759
OrthoFinder	1	1.000	-	-		FOG0000701
OrthoInspector	1	1.000	-	-		otm44787
orthoMCL	1	0.900	-	-		OOG6_103965
Panther	1	1.100	-	-	O	PTHR45688
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1960
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.840