DRSC/TRiP Functional Genomics Resources

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Protein Alignment Hml and Vit

DIOPT Version :9

Sequence 1:NP_524060.2 Gene:Hml / 39529 FlyBaseID:FBgn0029167 Length:3843 Species:Drosophila melanogaster
Sequence 2:NP_083089.1 Gene:Vit / 74199 MGIID:1921449 Length:650 Species:Mus musculus


Alignment Length:206 Identity:54/206 - (26%)
Similarity:78/206 - (37%) Gaps:62/206 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly   907 DPSCTKAVTIRFILRDGTPSVIK----------------LDQG----LTTIV--NDKP------- 942
            ||:|  .:.:.|:: ||:.|:.|                ||.|    |..:|  .|.|       
Mouse   259 DPNC--KIDLSFLI-DGSTSIGKRRFRIQKQFLADVVQALDIGPAGPLVGVVQYGDNPATQFNLK 320

  Fly   943 -----------IAKLPKMLGLGEVLIRRASSTFLTVEF---ADGIRVWWDGVSRVYIDAPPSLRG 993
                       |.|:.:..||..|  .||.| |:|..|   |:|.|.....|:.|.:|..|:.:.
Mouse   321 THMNSQDLKTAIEKITQRGGLSNV--GRAIS-FVTKTFFSKANGNRGGAPNVAVVMVDGWPTDKV 382

  Fly   994 QTQGLCGTFNSNTQDDFLTPEG----DVETAVEP-FADK--WRTKDTCQFKAETHQGPHPCTLNP 1051
            :....... .|.....|:|.||    |::..||| ||.|  .||.....|..::....|. |:.|
Mouse   383 EEVSRVAR-ESGINVFFITVEGAAERDIQHVVEPGFASKAVCRTNGFYSFNVQSWLSLHK-TVQP 445

  Fly  1052 EKKAQAEKFCD 1062
            ..|    :.||
Mouse   446 LVK----RVCD 452

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
HmlNP_524060.2 VWD 485..636 CDD:295339
C8 680..754 CDD:285899
TIL 758..811 CDD:280072
VWD 840..1015 CDD:214566 36/150 (24%)
C8 1054..1121 CDD:214843 3/9 (33%)
TIL 1131..1185 CDD:280072
TIL 1245..1298 CDD:280072
VWD 1327..1498 CDD:214566
C8 1535..1609 CDD:214843
Mucin2_WxxW 1751..1837 CDD:290069
TIL 1938..2005 CDD:280072
FA58C 2089..2223 CDD:238014
FA58C 2104..2225 CDD:214572
FA58C <2299..2404 CDD:214572
FA58C <2299..2403 CDD:238014
VWD 2703..2858 CDD:295339
C8 2893..2970 CDD:285899
TIL 2974..3030 CDD:280072
VWD 3035..3198 CDD:295339
C8 3257..3313 CDD:285899
VWC 3397..3451 CDD:302663
GHB_like <3755..3813 CDD:304424
VitNP_083089.1 LCCL 44..133 CDD:281766
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 198..226
vWFA 265..428 CDD:294047 44/167 (26%)
vWA_collagen 466..626 CDD:238749
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1216
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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