Protein Alignment Hml and Muc5b

DIOPT Version :10

• Sequence 1: NP_524060.2
• Gene: Hml / 39529
• FlyBaseID: FBgn0029167
• Length: 3843
• Species: Drosophila melanogaster
• Sequence 2: NP_083077.2
• Gene: Muc5b / 74180
• MGIID: 1921430
• Length: 4800
• Species: Mus musculus
• Alignment Length: 5126
• Identity: 1005/5126 - (19%)
• Similarity: 1520/5126 - (29%)
• Gaps: 2116/5126 - (41%)

  Fly   453 SSEETVVTMSSYSLY------QSNNLDIVIDKTPRPAL-----------CTTWGGINMKTFDGLV 500
            |||...:|..|..:|      .:.::..:...|..|::           |:|||..:.|||||.|
Mouse    32 SSEHLELTGDSQRVYSDSISSSTRHVTFIPPITVFPSMSALHLAHNGRVCSTWGDFHYKTFDGDV 96

  Fly   501 FKAPLSCSHTLITDKVSGT---FDIILKACPYGSGYGCAHTLKILWQSVLYTFENLNGTMQLTTP 562
            |:.|..|:: :.:.....|   |:|.|:....||.....:   :|.::.....|..||::.:...
Mouse    97 FRFPGLCNY-VFSSHCGATYEDFNIQLRRGLEGSRPTVTY---VLLRAQGLVIELSNGSVLVNGH 157

  Fly   563 IKKLPMPVQVMGMKVMPVAQHVQIDLESVGLKLDWDHRQYVSVQAGPQMWGKVGGLCGTLDGDPN 627
            .:||  |....|:.:...:.:|:|.:..| |...|:......::...:...:..||||..:|.|.
Mouse   158 REKL--PYSRAGLLMEKSSGYVKISIRLV-LTFLWNEEDSALLELDSKYINQTCGLCGDFNGLPA 219

  Fly   628 TDLTSRTGKKLATVKAFADAWRVEDRSELCQ------VENSAEMEFGMDSCEQSKLQKAVSVCER 686
            .........:|..|: |.:..:::..:|.||      |.|..:.|               .:|.|
Mouse   220 VSEFYTHNTRLTPVQ-FGNLQKLDGPTEQCQDVLPSAVSNCTDTE---------------DICRR 268

  Fly   687 LLANEKLGDCIKPFNYDALIRTCMADYCNCANREHPESCNCDAIAMLAKECAFKGIKLEHGWRNL 751
            .|.......|....:....:..|:.|.|.|      .:|.|...|..:::||..| .....||:.
Mouse   269 TLLGPAFDKCTALVDVSMYLDACVQDLCRC------PTCPCATFAEYSRQCAHAG-GYPQNWRHP 326

  Fly   752 EICPISCGFGRVYQACGPNVEPTCDSDLALPASKGACNEGCFCPEGTV---QYKEACITRELCPC 813
            ::|..:|.|...|:.|......||.:.......:..|.:|||||.|||   .....|:..|.|.|
Mouse   327 DLCNWTCPFNMEYRECSSPCVDTCSNPQRSQLCEDHCMDGCFCPPGTVLDDVRHLGCLPLEQCHC 391

  Fly   814 SLRGKEFKPESTVKKNCNTCTCKNGQWRCTEDKCGARCGAVGDPHYQTFDGKRYDFMGKCSYHLL 878
            :..|:.:.|..:...:|.:|||..|.|:|.:..|...|...|..|..|||.|.|:..|.|||.|.
Mouse   392 THGGRIYAPGESFNTSCRSCTCFGGLWKCKDLPCPGTCSVQGGSHIFTFDEKLYNVHGDCSYILT 456

  Fly   879 KTQNTSVEAENVACSGA----VSESMNFAAPDDPSCTKAVTIRFILRDGTPSVIKLDQGLTTIVN 939
            |           .|:.:    :.:.......|..:|.||||:.  |..| .:||::.......:|
Mouse   457 K-----------KCADSSFTVLVDLRKCGVTDTENCLKAVTLN--LNSG-DTVIRIQVNGAVFLN 507

  Fly   940 DKPIAKLPKMLGLGEVLIRRASSTFLTVEFADG--IRVWWDGVSRVYIDAPPSLRGQTQGLCGTF 1002
             ....::|  |..|.:.|.:.||.|:.|:...|  ::|....:.:|::....|.:||..||||.|
Mouse   508 -SIFTQMP--LSAGNITIFKPSSFFIIVQTGMGLQLQVQLVPLMQVFVRLDRSYQGQMCGLCGNF 569

  Fly  1003 NSNTQDDFLTPEGDVETAVEPFADKWRTKDTCQFKAETHQGPHPCTLNPEKKAQAEKFCDWILQD 1067
            |.|..|||....|.||.....|::.|:|:.:|.....|::  .||:.:.|.:..|.::|..:.:.
Mouse   570 NQNQADDFTALSGVVEGTGAAFSNTWKTQASCPNSKNTYE--DPCSYSVENENFAREWCSMLTES 632

  Fly  1068 --IFQDCHFLVEPEQFYEDCLYDTCACKDEMSKCFCPILSAYGTECMRQGV-KTGWRMSVKEC-- 1127
              :|..||..|.|..||.:||:|||.|::. ..|.|..||:|...|..:|| .:|||..|  |
Mouse   633 SGVFSACHATVSPVPFYSNCLFDTCNCENS-EDCMCAALSSYVFACAAKGVLLSGWRDKV--CYK 694

  Fly  1128 -AVKCPLGQVFDECGDGCALSCDDLPSKG---SCKRECVEGCRCPHGEYVNEDGECVPKKMCHCN 1188
             ...||..:.:......|..:|..|....   |.....|:||.||.|.::|:...|||.:.|.|.
Mouse   695 YTNNCPQTKGYFYSVSSCQPTCRSLSEADVTCSVPFVTVDGCTCPEGTFLNDKDHCVPVEECPCY 759

  Fly  1189 FDGMSFRPGYKEVRPGEKFLD---LCTCTDGVWDCQDAEPGDKDKYPPSSELRSKC-AKQPYAEF 1249
            |.|       ..|.|.|...|   :|:||:|...|..|          ..:..::| |...|.:.
Mouse   760 FHG-------TVVAPREVVTDNGVVCSCTNGKLTCLGA----------LMQKSTECQAPMVYLDC 807

  Fly  1250 ---------TKCAPKEPKTCKNMDKYVADSSDCLPGCVCMEGYVYDTSRLACVLPANCSCHHAGK 1305
                     .:|.    |:|..:| ....|:.|:.||||..|.|.|.:. .|:...:|.|.|...
Mouse   808 NNASVGHHGAECL----KSCHTLD-VECFSTQCVSGCVCPSGLVADGNG-GCIAEEDCPCIHNEV 866

  Fly  1306 SYDDGEKIKEDCNLCECRAGNWKCSKNGCESTCSVWGDSHFTTFDGHDFDFQGACDYVLA----K 1366
            :|..||.|:.|||.|.|:...|:|:...|...|..:||.||.||||..:.|:|:|:|.||    :
Mouse   867 TYRPGEIIRVDCNNCTCKNRRWECTNKPCMGACVAYGDGHFVTFDGERYIFEGSCEYTLAQDYCR 931

  Fly  1367 GVFDNGDGFSITIQNVLCGTMGVTCSKSLEIALTGHAEESLLLSAD-SAYSTDPNKTPIKKLRDS 1430
            |.......|.|..:||.|||.|.||||:::|.:..:  |.:|...: ......|:..|..|:|
Mouse   932 GNTSTNGTFRIVTENVPCGTTGTTCSKTIKIFVESY--ELILHEGNFKVVEQGPSGDPPYKIR-- 992

  Fly  1431 VNSKGHNAFHIYKAGVFVVVEVIPLKLQVKWDEGTRVYVKLGNEWRQKVSGLCGNYNGNSLDDMQ 1495
                        ..|:|:|:| |...:.|.||..|.|:|:|...::.:|.|||||::.|:::|..
Mouse   993 ------------FMGIFLVIE-IRSGIVVSWDRKTSVFVRLQQHYKGRVCGLCGNFDDNAINDFT 1044

  Fly  1496 TPSMGLETSPMLFGHAWKLQPHC-SAPVAPIDACKKHPERETWAQLKCGALKSDLFKECHAEVPL 1559
            |.|..:....:.||::||..|.| .||| |.|.|..:|.|::|||.||..:.|..|..||::|..
Mouse  1045 TRSQSVVGDVLEFGNSWKFSPSCPDAPV-PKDPCIANPYRKSWAQKKCSIINSATFAACHSQVDS 1108

  Fly  1560 ERFWKRCIFDTCACDQGGDCECLCTAVAAYADACAQKGINIRWRSQHFCPMQCD---PH--CS-D 1618
            .::::.|:.|.||||.||||||.||||||||.||...|:.:.||:...||:.||   ||  |. .
Mouse  1109 TKYYEACVHDVCACDSGGDCECFCTAVAAYAQACRDVGVCLSWRTPDICPLFCDYYNPHGECEWH 1173

  Fly  1619 YKACTPACAVETCDNFLDQGIAERMCNRENC------LEGCHIKPCEDGFIYLNDTYRDC----- 1672
            |:.|...| ::||.|           ...:|      ||||: ..|.....:.|:....|
Mouse  1174 YQPCGAPC-LKTCRN-----------PTGHCLVDLPGLEGCY-PQCPASQPFFNEDQMKCVAQCG 1225

  Fly  1673 --------------VPKAE------CKP---VCMVR--------DGKTFYEGDITF--TDSCATC 1704
                          ||.||      |.|   .|:..        :|:|:...|:.:  ||....|
Mouse  1226 CYDDNGNYHDIGTQVPTAENCQSCLCTPGGLQCVYNLTACTCTYEGRTYNYNDVVYNTTDGLGAC 1290

  Fly  1705 ---------RCSKRKEICSGVKCDVPATTGLPAPLVEGTTLPTPLATQN-----QTKCVK---GW 1752
                     ..::..|:|.    :||:||    |....||| .||||..     .|.||.   .|
Mouse  1291 LVAICKDNGTIARTTEVCH----EVPSTT----PFTFTTTL-APLATNGSASTVSTVCVHEVCQW 1346

  Fly  1753 TRWCDKDRDTSDKSVRLNDEEKVPRYDRMENV----YGTCLKQYMTKVECR-VKDTHEAPEQMDE 1812
            :.|.|:....:..|.  .|      ::..||:    :..|  |....:||| ||......|::.:
Mouse  1347 SIWYDESHPEAGMSG--GD------FETFENLRKKGHQVC--QTPVGIECRAVKFPSMDLEKLGQ 1401

  Fly  1813 NVVCSLEEGLRCIGK------CHDYELRAFCQCD------------------------------- 1840
            .|.|....||.|...      |||||||..| ||
Mouse  1402 KVNCDPSSGLSCFNSEQSPPLCHDYELRVLC-CDYVPCGSSLTLGISTTPSQPDTSRRPSSPTLT 1465

  Fly  1841 -------------EELEPELPK-------------------------------PT---------- 1851
                         ||.:..:.|                               ||
Mouse  1466 THTASSESQSWTREEKKTSVDKSYSSRQTVPFTSNSRLTSTSMSSASSLPLSNPTWTTTLKATDE 1530

  Fly  1852 ----------------------------------------------------------------- 1851
                                                                             
Mouse  1531 NTMLSSRTTAVFTSQTRSTSRPSTVTQPISSPETSSTTCQPQCQWTKWIDVDYPSSSINGGDIET 1595

  Fly  1852 ------------EKPQ----------------LG--LACD--AAVVEYKEFPGD----CHKFL-- 1878
                        ||||                ||  :.||  :.:|.|.:..|.    |:.:|
Mouse  1596 YENIRANGEKICEKPQDIRCMAQNHPGVNVDELGQKVKCDVSSGLVCYNKDQGGTFQMCYNYLIK 1660

  Fly  1879 -------HCQPKGVEGGWIYVEKTC---------------GEYMMFNP----------------- 1904
                   |||......|.:...:|.               ..:..::|
Mouse  1661 VLCCSVSHCQGSTTPEGSVSTTETATSTPQTLSSKPLPNTSSFETWSPSGPTTSMEASEMPTFWT 1725

  Fly  1905 ---------------TMLICDH-----------IATVTEIKPNCGLKPE---------------- 1927
                           |.:...|           :.|.........|.|.
Mouse  1726 LRTSVSSPPTTPLTVTSVSTQHPKSLESSGSPSVVTARSTSQGYSLPPSSPHTTNSLSATTSKAS 1790

  Fly  1928 -------------PEPEFEP---------------------IKQCPPGKIKSE------------ 1946
                         |.|...|                     :...|..|..||
Mouse  1791 LSSMTTISTSLTTPGPSSPPHGGTTTHPVTTASTTRAVTETLSSRPHTKTTSELPTVSSASSTAG 1855

  Fly  1947 ---------CANQCENT----CHYYGSI-----------LKKRG--LCQVGEHCKPGCVDELRP- 1984
                     |..||:.|    ..|..|.           ::..|  :|:..:..:  |:.:..|
Mouse  1856 PGTQTFSTTCQPQCQWTKWIDVDYPSSSINGGDIETYENIRANGEKICEKPQDIR--CMAQNYPG 1918

  Fly  1985 -DCPKLGKFWRDEDTCVHADECPCMDKAEHYVQPHKPVLGEFEVC-------------QC----- 2030
             :..|||:    :..|..:....|.:|.:.         |.|.:|             .|
Mouse  1919 VNVDKLGQ----KVKCDVSSGLVCYNKDQG---------GTFPMCYNYLIKVLCCSVSHCQGSTT 1970

  Fly  2031 ------IDNAFTCVP----NKPEP--------VPKDEDDDLDL------------VSVVPIYPVT 2065
                  .....|..|    :||.|        .|......::.            ||..|..|:|
Mouse  1971 PEGSVSTTETTTATPQTLSSKPLPNTSSIETWSPSGPTTSMEASEMPTFWTLRTSVSSPPTTPLT 2035

  Fly  2066 LT-------PPLQC--SPERLIPKIENPAHSLPDSIFNASSQL---------------------- 2099
            :|       ..|:.  ||..:..:..:|.||.|.|...|::.|
Mouse  2036 VTSVSTQHPKSLESSGSPSVVTARSTSPGHSQPPSSPYATNSLSATTSKASLSSMTTISTSLTTP 2100

  Fly  2100 ---APEHG--------------------------------PKMARL------------------- 2110
               :|.||                                |.::.:
Mouse  2101 GPSSPPHGGTTTHPVTTASTTRAVTETLSSRPHTKTTSELPTVSSVSSTAGPGTQTGSTSRPNTV 2165

  Fly  2111 -----------TKEQPRGSWSPSINDQMQYLELNFAKPEPFYGVVMAGSPEFDNYVTLFKILHSH 2164
                       |..||:..|:..|:.......:|....|.:..:...|....:....:..:..:|
Mouse  2166 TQPASSPETSSTTCQPQCQWTKWIDVDYPSSSINGGDIETYENIRANGEKICEKPQDIRCMAQNH 2230

  Fly  2165 DGI------------------------------AYHYLV------------------------DE 2175
            .|:                              .|:||:                        ..
Mouse  2231 PGVNVDELGQKVKCDVSSGLVCYNKDQGGTFQMCYNYLIKVLCCSVSHCQGSTTPEGSVSTTETT 2295

  Fly  2176 TEKPQMFNG-PLDSRAPVQTLF----KIPIEASSLRIYPLKW----------------------- 2212
            |..||..:. ||.:.:.::|..    ...:|||.:   |..|
Mouse  2296 TATPQTLSSKPLPNTSSIETWSPSGPTTSMEASEM---PTFWTLRTSVSSPPTTPLTVTSVSTQH 2357

  Fly  2213 ------HGS--------------------------------------IAMRVELLICGDKEEP-- 2231
                  .||                                      ..:...|...|....|
Mouse  2358 PKSLESSGSPSVVTARSTSPGHSQPPSSPYATNSLSATTSKASLSSMTTISTSLTTPGPSSPPHG 2422

  Fly  2232 ----KPVPTVSTILPITE----------------------------------RPARLV------- 2251
                .||.|.||...:||                                  ||..:.
Mouse  2423 GTTTHPVTTASTTRAVTETLSSRPHTKTTSELPTVSSVSSTAGPGTQTGSTSRPNTVTQPASSPE 2487

  Fly  2252 ------------------------------------------------DLECIDL----MGVDE- 2263
                                                            |:.|:..    :.|||
Mouse  2488 TSSTTCQPQCQWTKWIDVDYPSSSINGGDIETYENIRANGEKICEKPQDIRCMAQNHPGVNVDEL 2552

  Fly  2264 GKMYQDQVQSSSLWQQPNLGKKLQ-----LLELL--------KLSTPLAWRPLANSQNEFIEFDF 2315
            |:..:..|.|..:....:.|...|     |:::|        :.:||....|...:
Mouse  2553 GQKVKCDVSSGLVCYNKDQGGTFQMCYNYLIKVLCCSVSHCQRSTTPAGSAPTTGT--------- 2608

  Fly  2316 LEPRNISGFVTKGGPDGW----------------------------------------------- 2333
             .|...||..|.   ..|
Mouse  2609 -APTATSGTATH---TSWPASSMPTSTTESPSSSGKTTILTTASSLATGTPRETQTSSLLTTGLS 2669

  Fly  2334 ----VTGYKVMFSKKKPTWNTVLSTD----GQARIFEANHDAETERRHHFKNPILTQYIK----- 2385
                .||......|.:.||...|.:|    ||   ||.  |.||  .:|.:|....:..|
Mouse  2670 SALTTTGTTSTGCKSQCTWTDWLDSDKPQPGQ---FEG--DIET--YYHIQNKTGIKICKKPVDI 2727

  Fly  2386 -----IVPAYWEKNINMRIEPLG-----------------------CF----------------- 2405
                 :.|       |:..:.||                       ||
Mouse  2728 ECEAVLFP-------NISFQKLGQEVVCNVDFGLICRNSKQSDNQICFNYHIRVLCCEEDTSCIS 2785

  Fly  2406 --------------------------LP-----------------YPEIQRQVPV---------- 2417
                                      ||                 .|..::.|.:
Mouse  2786 TTGLLSTTSTSAPGFPSTVSTSTTSKLPSEEPIPSTSFTTQSRPSTPRTEKIVSIATARTTGSFP 2850

  Fly  2418 ------------------EE--------------------SKP----------TKCNICDGVSTS 2434
                              ||                    :||          ||..:.:.:.:|
Mouse  2851 VSSLSTFPASPTSLLPTSEEPHSGKPSTSSWTASSNVPSTAKPTTSTGRQFPRTKTTLWNSLPSS 2915

  Fly  2435 S-----------STTGCQCQDQLFWDGNTCVQHNLCP----CIENYVSYPIGSKFENSACEDCVC 2484
            :           |||......|.....:....:::.|    ...:.|:...||:...|.....:.
Mouse  2916 TPTMATRSIHPISTTMTTKNPQTLVTSDISKSNSMLPSRPHITASSVTSTSGSQISKSYSSTSLT 2980

  Fly  2485 VLGGHKNCKPKKCPPCLGGKLRPVITSDC------FCKCEPCPKHQRLCP--------------- 2528
            ..|       ...||..|....||.|:..      .....|..|.....|
Mouse  2981 TAG-------PSSPPHGGTTTHPVTTASTTRAVTETLSSRPHTKTTSELPTVSSVSSTAGPGTQT 3038

  Fly  2529 ------------------SSGDCIPEILW-------------------------CNGVQDCADDE 2550
                              ||..|.|:..|                         .||.:.|...:
Mouse  3039 GSTSRPSIVTQPVSSPETSSTTCQPQCQWTRWINVDYPSSSINGGDIETYENIRANGEKICEKPQ 3103

  Fly  2551 DASCS---------DSF--TVEPDV-------SREKNET---------EVITCPVPVC----PPQ 2584
            |..|.         |..  .|:.||       ::::..|         :|:.|.|..|    .|:
Mouse  3104 DIRCMAQNYPGVNVDELGQKVKCDVNSGLVCYNKDQGGTFKMCYNYLIKVLCCSVSHCQGSTTPE 3168

  Fly  2585 MKIRITE----------------------------KKSRKMSKMFTF-SKQVSIVDDGTT-ITKT 2619
            ..:..||                            ..|.:.|:|.|| :.:.|:....|| :|.|
Mouse  3169 GSVSTTETASSIPQTLSSKPLPNTSSFETWSPSGPTTSMEASEMPTFWTLRTSVSSPPTTPLTVT 3233

  Fly  2620 KF-----------------------------------------ISSKEQILAMPNRELDFQLEE- 2642
            ..                                         .:||..:.:|..........|
Mouse  3234 SVSTQHPKSLESSGSPSVVTARSTSQGHSLPPSSPHTTNSLSATTSKASLSSMTTISTSLTTSEP 3298

  Fly  2643 ---------------------------------QCDEFTCVPIPSKQV----------------- 2657
                                             ...|...||..|...
Mouse  3299 SSPPHGGTTTHPVTAASTTRAVTETLSSRPHTKTTSELPTVPSASSTAGPGTQTGSTSRPSTVTQ 3363

  Fly  2658 ----DKNETVTCTEPKCPEKYDVELDMSASKV--GDCLRYSCVLRPNKDDVCE------------ 2704
                .:..:.|| :|:|.....:::|..:|.:  ||...|..: |.|.:.:||
Mouse  3364 PASSPETSSTTC-QPQCQWTKWIDVDYPSSSINGGDIETYENI-RTNGEKICEKPQDIRCMAQNH 3426

  Fly  2705 -------------------------ISGKSF---------------------TTFDGTVFKYG-- 2721
                                     ..|.:|                     ||..|:....|
Mouse  3427 PGVNVDELGQKVKCDVNSGLVCYNKDQGGTFQMCYNYLIKVLCCSVSHCQGSTTTPGSAPMTGSA 3491

  Fly  2722 ------------PCSHILARDIHSSSW--SISVHQQCSDETRKVCHKV-------------ITIQ 2759
                        |.:.:.....||:|.  :.|:.:..|..:....|..             :|.|
Mouse  3492 TTATQTLSSMPLPNTSLTVTSPHSASTTAATSITETSSPRSVSSIHTTPKIFPETLQSTTGLTTQ 3556

  Fly  2760 DTE------------AG--NELILLPHLKLKFNGYEFTVQQLINS--PICKASFVVSQPGKTLLA 2808
            .|.            ||  :...|...|:......|.:....:.|  |:...:....| |.||..
Mouse  3557 QTSSTGIWTSMLTGTAGTVSSTSLSTSLESTTGITEVSTSMPMTSTLPVTVTNATTPQ-GTTLCQ 3620

  Fly  2809 VSTKYGFWVQLDD---------------------------------------IGIVKVG-ISSKF 2833
            ...|:..|..:|.                                       :.|.||| :.|..
Mouse  3621 PKCKWTEWFDVDSPTSGSVKGDMETYENIRASGKTLCQAPEKIECRAENYPAVSIDKVGQVVSCN 3685

  Fly  2834 IRTVDGL-CGYYNGNQKDDKR-------------------------------------------- 2853
            :.|  || |  .|.:||||.:
Mouse  3686 LET--GLVC--KNEDQKDDFKMCFNYNIRVLCCDDYSHCPTTTYTTIKSPLAPFTTSVSSSMEST 3746

  Fly  2854 -------SPDGQIIPNTE-----KFGDS----------WYDKRIPK------------------- 2877
                   ||.|   |:|:     ...||          |:|...|.
Mouse  3747 FQTNRPASPSG---PSTQASTWSTLPDSGCTPRCKWTEWFDADYPNPGPRGGDFEVYAVFREVGY 3808

  Fly  2878 ---DQCGDLKC--------PREMQAKALQLCNIIHHPTFARCHKAVNYK---QFLNNY-----CL 2923
               ||..|::|        |.|...:.:| |::    .|....|.:|..   |:.:||     |.
Mouse  3809 IFCDQPKDIECRSEKEPDRPLETLEQVVQ-CDV----RFGLICKNINQSGPLQYCDNYHVRLLCC 3868

  Fly  2924 EAACNC-----------------------------------------------------MMANNG 2935
            :...:|                                                     |:....
Mouse  3869 DNYSHCTSSPMATMSTALSSSHLPSTHTSLALNTTTFFPGLSSSSEPHSSSLMSTHTSTMLTTET 3933

  Fly  2936 DPAACKCNILES------FVKKCLSVNPLVQLT------------TWRAVAQCEINCPSP----- 2977
            .|.|....:..|      :..|   |:|..|:|            |.|.|.....:.|||
Mouse  3934 SPIATGPTVAPSSTSGTPYTPK---VSPSSQVTFSVSTAFSSVFSTPRPVFSSHASSPSPCFCQA 3995

  Fly  2978 ---------LVH-------------------TDCYKRRCEPSCDNVHGDDCPVLPDACFPGC--Y 3012
                     :::                   .|.::..|..|...:.....|:.|  ..|||  .
Mouse  3996 FGQLFLPGDIIYNKTDGAGCQFYAICNQYCDVDRFQGTCPSSSPPMSSTTVPLPP--LLPGCDNA 4058

  Fly  3013 CPEGTVRKG---PNC----------------------------VPIS-----------ECKDCVC 3035
            .|...|.:.   .||                            :||.           || :|.|
Mouse  4059 IPPRQVNESWTLENCTVARCQGNNQIILLEPEPVDNVTCANRHLPIKVWDQEPCHFHYEC-ECFC 4122

  Fly  3036 NSLGASKYMTYDRKSFSFNGNCTYLLSRDVVLPGVHTFQVYVSMDDCKKLGQPTPVEGGSCAKSL 3100
            :..|.|.|:|:|..|::|..|||.:|.|: :.|......:......|   |..|.|.  ||.::|
Mouse  4123 SGWGHSHYLTFDGTSYTFLDNCTSVLMRE-IHPRHGNLSILAHSYYC---GATTNVT--SCPRAL 4181

  Fly  3101 HI-LNGDHVIHVQRVPQKPKSLQVLVDGFEVKKIPYKDSWISLRQVVGKELV---------LSLP 3155
            .: .|...:|         .::.....|.:...|.:...||  |....|..|         :|:.
Mouse  4182 SVYYNSMEII---------LTISTTESGKDESLIIWDQMWI--RSGFSKNGVTVSLSGATTMSVN 4235

  Fly  3156 ESHVELTASFEDLIFSLGVPSIKYGSKMEGLCGDCNGNAGNDL-QPNPAKKKAGVDVIQSWQADE 3219
            .|.:....:|:..||.:.:|...:.|..||.||.|..:..:|. :|:........|:.:.|
Mouse  4236 ISTIGTIITFDGNIFQIWLPYRYFSSNTEGQCGTCTNSQIDDCRRPDGTIASDCQDMAKEW---- 4296

  Fly  3220 PKLGLV-----EECLSEDVPKEHCIPLPP-----EKDPC-----LQFYNAELFGKCPLAVDPIAY 3269
                ||     ..||::..|.....|..|     ...||     .:...:::|.:|...:.|.|:
Mouse  4297 ----LVPGNSSSSCLAQPSPLPSTTPQTPVSSTLTSTPCPSAPLCELMLSQVFAECHRLIPPDAF 4357

  Fly  3270 VSACQQDICKPGNTQQGVCVALAAYAKECNQHGICTNWRRPQ--LCPYECPSDMVYEPCGCAKNC 3332
            ..:|..|.|. .|....:|.:|.|||..|...|:|||||...  ||...||....|.|||
Mouse  4358 FRSCVSDHCN-ANITDMLCQSLEAYAALCRAQGVCTNWRNATGGLCDLSCPPTKEYRPCG----- 4416

  Fly  3333 DTIKALSEFDAVSLKNEAVVHTVKTDEMCLSSER---FEGCFCPPGKVMDGGQ---CVPEIACTK 3391
                              .:|....:.....|..   .||||||..:::...:   ||.|..|..
Mouse  4417 ------------------PLHPASCNSRTQDSTTGMLAEGCFCPENQLLFNSRMDICVSECPCVG 4463

  Fly  3392 CDDGLHLPDEKWKKDKCTECQCD-SKGKTTCVEKKCQVEEN--ICAE-GYRPETIVSVDE-CCPR 3451
            .|.....|.|.|..: |..|.|: ......|...||:.::.  .|.| |:...|..|.|. |||.
Mouse  4464 PDGLPKFPGEHWISN-CQACVCEPGSVSVQCEPVKCESQDKPPQCTEAGFVTVTWPSADNPCCPE 4527

  Fly  3452 YRCV-PETKDPSKLCLAPLVPICGPGQFKKEKKDVNGCSQYICECIPKDQCEIIELRELLPGEII 3515
            ..|| ..|..|..|      |.|.||.                        |:::..|
Mouse  4528 TLCVCNSTTCPKSL------PTCEPGY------------------------ELVQTHE------- 4555

  Fly  3516 VNVEEGCCPTQKIECKPETCPKAPVNCQERFYEVKTIKEPGMCCSKHSCVPPKDLCIVQYELDEA 3580
               ...|||:  ..|:|:.|     ...:..|.|.|....|.|   |:|....|
Mouse  4556 ---NSSCCPS--YSCRPKLC-----TYNDTIYGVGTTFPGGPC---HTCTCLSD----------- 4596

  Fly  3581 TKFTKTVGDKWTHAKEVCKQETCSYGPDGNAQVVSTLEQCLTDCAPGFSYQNLDKTKCCGKCVQT 3645
                   ||:  ..|..||:..|:                 |.|..||.| .|...:|||:|:|.
Mouse  4597 -------GDQ--EPKVECKETNCT-----------------TSCPQGFKY-TLVPEQCCGECLQN 4634

  Fly  3646 SCIF-EQKLYEVNALWKSA--DNCTTYSCLKKDGQFLVTTSREVCPDVGSCLSHLLYQDGCCKRC 3707
            :|:. |....:.|..|.::  ||||.|.|:.::|.:::|.....||||.:| :..|.:.|||..|
Mouse  4635 ACLTPEGHAVQPNETWVNSPVDNCTAYHCMAENGVYVLTPIPTSCPDVSNC-TGTLRKTGCCYSC 4698

  Fly  3708 KSEPLVEDKSSC-LPVSLAESRTKEILKFPVQGHGTCVNADPIQGFTDCEGACSSGSKYNTLTDM 3771
            :.    ||.|:| :.|:....|.|        |..|.||      .|.|||:||..|||:.....
Mouse  4699 EK----EDSSTCQVHVNATVLRYK--------GCETEVN------ITFCEGSCSGISKYSMEAQA 4745

  Fly  3772 HEKFCTCCSIKSYHPISVKMICDDG----HTFTQKHEVPSNCGCSP-CSEFSDSAI 3822
            .|:.||||.....|.::|.|.|.||    ||:|...|    |.|:| ||....:::
Mouse  4746 MERQCTCCQESKVHDVAVTMQCPDGTVIQHTYTHIDE----CNCAPACSSLPGTSM 4797

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hml	NP_524060.2	VWD	485..636	CDD:459671	38/153 (25%)
		C8	684..754	CDD:462584	16/69 (23%)
		TIL	758..811	CDD:410995	17/55 (31%)
		VWD	840..1015	CDD:214566	53/180 (29%)
		C8	1054..1121	CDD:214843	24/69 (35%)
		TIL	1131..1185	CDD:410995	16/56 (29%)
		TIL	1245..1298	CDD:460351	15/61 (25%)
		VWD	1327..1498	CDD:214566	59/175 (34%)
		C8	1535..1609	CDD:214843	35/73 (48%)
		TIL	1938..2005	CDD:473303	18/106 (17%)
		FA58C	2089..2223	CDD:238014	34/346 (10%)
		FA58C	<2299..2403	CDD:238014	25/168 (15%)
		VWD	2703..2858	CDD:459671	48/349 (14%)
		TIL	2974..3030	CDD:460351	17/132 (13%)
		VWD	3035..3198	CDD:459671	42/172 (24%)
		C8	3248..3313	CDD:462584	21/71 (30%)
		VWC	3397..3451	CDD:450195	17/58 (29%)
		GHB_like	<3755..3813	CDD:473907	25/61 (41%)
Muc5b	NP_083077.2	VWD	80..227	CDD:214566	38/153 (25%)
		C8	265..329	CDD:462584	16/70 (23%)
		TIL	333..389	CDD:410995	17/55 (31%)
		VWC_out	391..>436	CDD:214565	13/44 (30%)
		VWD	429..583	CDD:459671	50/170 (29%)
		C8	619..700	CDD:214843	28/83 (34%)
		TIL	699..756	CDD:410995	16/56 (29%)
		TIL	798..859	CDD:410995	17/66 (26%)
		VWD	888..1047	CDD:214566	59/175 (34%)
		C8	1084..1158	CDD:214843	35/73 (48%)
		Mucin2_WxxW	1346..1432	CDD:463846	27/95 (28%)
		Mucin2_WxxW	1575..1663	CDD:463846	13/87 (15%)
		PLN02217	<1687..1796	CDD:215130	6/108 (6%)
		Metaviral_G	<1742..1864	CDD:462833	11/121 (9%)
		Mucin2_WxxW	1871..1959	CDD:463846	16/102 (16%)
		Herpes_BLLF1	<1968..2181	CDD:282904	27/212 (13%)
		Mucin2_WxxW	2185..2273	CDD:463846	10/87 (11%)
		Herpes_BLLF1	<2282..2495	CDD:282904	25/215 (12%)
		Mucin2_WxxW	2499..2587	CDD:463846	11/87 (13%)
		Mucin2_WxxW	2688..2776	CDD:463846	19/101 (19%)
		DUF5585	2827..>3082	CDD:465521	33/261 (13%)
		Herpes_BLLF1	2909..3626	CDD:282904	101/726 (14%)
		Mucin2_WxxW	3067..3155	CDD:463846	12/87 (14%)
		Mucin2_WxxW	3381..3469	CDD:463846	11/88 (13%)
		Mucin2_WxxW	3625..3713	CDD:463846	16/91 (18%)
		Mucin2_WxxW	3779..3867	CDD:463846	17/92 (18%)
		VWD	4111..4283	CDD:214566	47/189 (25%)
		C8	4336..4398	CDD:462584	20/62 (32%)
		VWC	4570..4631	CDD:214564	24/106 (23%)
		CT	4708..4790	CDD:214482	34/99 (34%)