|
Fly 484 LCTTWGGINMKTFDGLVFKAPLSCSHTLITDKVSGT---FDIILKACPYGSGYGCAHTLKILWQS 545
:|:|||..:.|||||.||:.|..|:: :.::..... |::.|:....||. ....:::.::
Human 76 VCSTWGDFHYKTFDGDVFRFPGLCNY-VFSEHCRAAYEDFNVQLRRGLVGSR---PVVTRVVIKA 136
Fly 546 VLYTFENLNGTMQLTTPIKKLPMPVQVMGMKVMPVAQHVQIDLESVGLKLDWDHRQYVSVQAGPQ 610
.....|..||::.:....::| |....|:.|.....::::.:..| |...|:......::..|:
Human 137 QGLVLEASNGSVLINGQREEL--PYSRTGLLVEQSGDYIKVSIRLV-LTFLWNGEDSALLELDPK 198
Fly 611 MWGKVGGLCGTLDGDPNTDLTSRTGKKLATVKAFADAWRVEDRSELCQVENSAEMEFGMDSCEQS 675
...:..||||..:|.|..:.......:|..:: |.:..:::..:|.| ...:.....:|...
Human 199 YANQTCGLCGDFNGLPAFNEFYAHNARLTPLQ-FGNLQKLDGPTEQC----PDPLPLPAGNCTDE 258
Fly 676 KLQKAVSVCERLLANEKLGDCIKPFNYDALIRTCMADYCNCANREHPESCNCDAIAMLAKECAFK 740
: .:|.|.|......:|....:..|.:..|..|.|.| .:|.|......:::||..
Human 259 E-----GICHRTLLGPAFAECHALVDSTAYLAACAQDLCRC------PTCPCATFVEYSRQCAHA 312
Fly 741 GIKLEHGWRNLEICPISCGFGRVYQACGPNVEPTCDSDLALPASKGACNEGCFCPEGTVQ---YK 802
|.: ...||..|:||.:|.....:|.||.....||.:.......:..|.:|||||.|||. ..
Human 313 GGQ-PRNWRCPELCPRTCPLNMQHQECGSPCTDTCSNPQRAQLCEDHCVDGCFCPPGTVLDDITH 376
Fly 803 EACITRELCPCSLRGKEFKPESTVKKNCNTCTCKNGQWRCTEDKCGARCGAVGDPHYQTFDGKRY 867
..|:....|||:..|:.:.|.::....|::|||..|.|:|.:..|...|...|..|..|:|.|.|
Human 377 SGCLPLGQCPCTHGGRTYSPGTSFNTTCSSCTCSGGLWQCQDLPCPGTCSVQGGAHISTYDEKLY 441
Fly 868 DFMGKCSYHLLK---TQNTSVEAENVACSGAVSESMNFAAPDDPSCTKAVTIRFILRDGTPSVIK 929
|..|.|||.|.| ..:.:|.||...| ...|:.:|.||||:.. ||..:.|:
Human 442 DLHGDCSYVLSKKCADSSFTVLAELRKC----------GLTDNENCLKAVTLSL---DGGDTAIR 493
Fly 930 L--DQG--LTTIVNDKPIAKLPKMLGLGEVLIRRASSTFLTVEFADGIR--VWWDGVSRVYIDAP 988
: |.| |.:|....| |....:.:...||.|:.|:...|:: |....:.:|::...
Human 494 VQADGGVFLNSIYTQLP-------LSAANITLFTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRLD 551
Fly 989 PSLRGQTQGLCGTFNSNTQDDFLTPEGDVETAVEPFADKWRTKDTCQFKAETHQGPHPCTLNPEK 1053
|:.:||..||||.||.|..|||....|.||.....||:.|:.:..|.....:.: .||:|:.|.
Human 552 PAHQGQMCGLCGNFNQNQADDFTALSGVVEATGAAFANTWKAQAACANARNSFE--DPCSLSVEN 614
Fly 1054 KAQAEKFCDWIL--QDIFQDCHFLVEPEQFYEDCLYDTCACKDEMSKCFCPILSAYGTECMRQGV 1116
:..|..:|..:. ...|..||.::.|:.|:.:|::|||.| :....|.|..||:|...|..:||
Human 615 ENYARHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNC-ERSEDCLCAALSSYVHACAAKGV 678
Fly 1117 K-TGWRMSVKECA---VKCPLGQVFDECGDGCALSCDDLPSKG-SCKREC--VEGCRCPHGEYVN 1174
: :.||..| |. ..||..|.:....|.|..:|..|.... :|.... |:||.||.|.::|
Human 679 QLSDWRDGV--CTKYMQNCPKSQRYAYVVDACQPTCRGLSEADVTCSVSFVPVDGCTCPAGTFLN 741
Fly 1175 EDGECVPKKMCHCNFDGMSFRPGYKEVRPGEKFLDLCTCTDGVWDCQDAEPGDKDKYPPSSELRS 1239
:.|.|||.:.|.|...|....|| ||...|. .:|:||.|...|..| |.:..:
Human 742 DAGACVPAQECPCYAHGTVLAPG--EVVHDEG--AVCSCTGGKLSCLGA----------SLQKST 792
Fly 1240 KC-AKQPYAEFTKCAPKEP-----KTCKNMDKYVADSSDCLPGCVCMEGYVYDTSRLACVLPANC 1298
.| |...|.:.:..:...| ::|..:| ....|:.|:.||||..|.|.|.|. .|:...:|
Human 793 GCAAPMVYLDCSNSSAGTPGAECLRSCHTLD-VGCFSTHCVSGCVCPPGLVSDGSG-GCIAEEDC 855
Fly 1299 SCHHAGKSYDDGEKIKEDCNLCECRAGNWKCSKNGCESTCSVWGDSHFTTFDGHDFDFQGACDYV 1363
.|.|...:|..||.|:.|||.|.||...|:||...|..||..:||.||.||||..:.|:|:|:|:
Human 856 PCVHNEATYKPGETIRVDCNTCTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDRYSFEGSCEYI 920
Fly 1364 LAKGVFDNGDG-----FSITIQNVLCGTMGVTCSKSLEIALTGHAEESLLLSADS--AYSTDPNK 1421
||:... ||. |.|..:|:.|||.|.||||::::.:..: .|:|...: |.:..|..
Human 921 LAQDYC--GDNTTHGTFRIVTENIPCGTTGTTCSKAIKLFVESY---ELILQEGTFKAVARGPGG 980
Fly 1422 TPIKKLRDSVNSKGHNAFHIYKAGVFVVVEVIPLKLQVKWDEGTRVYVKLGNEWRQKVSGLCGNY 1486
.|..|:| ..|:|:|:|. ..:.|.||..|.|:::|..:::.:|.|||||:
Human 981 DPPYKIR--------------YMGIFLVIET--HGMAVSWDRKTSVFIRLHQDYKGRVCGLCGNF 1029
Fly 1487 NGNSLDDMQTPSMGLETSPMLFGHAWKLQPHCSAPVAPIDACKKHPERETWAQLKCGALKSDLFK 1551
:.|:::|..|.|..:....:.||::|||.|.|...:||.|.|..:|.|::|||.:|..|....|.
Human 1030 DDNAINDFATRSRSVVGDALEFGNSWKLSPSCPDALAPKDPCTANPFRKSWAQKQCSILHGPTFA 1094
Fly 1552 ECHAEVPLERFWKRCIFDTCACDQGGDCECLCTAVAAYADACAQKGINIRWRSQHFCPMQCD--- 1613
.|.::|...::::.|:.|.||||.||||||.||||||||.||...|:.:.||:...||:.||
Human 1095 ACRSQVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQACHDAGLCVSWRTPDTCPLFCDFYN 1159
Fly 1614 PH--CS-DYKACTPACAVETCDNFLDQGIAERMCNRENC------LEGCHIKPCEDGFIYLNDTY 1669
|| |. .|:.|...| ::||.| ..| :| ||||:.| |.....:.|:..
Human 1160 PHGGCEWHYQPCGAPC-LKTCRN--PSG---------HCLVDLPGLEGCYPK-CPPSQPFFNEDQ 1211
Fly 1670 RDCVPKAECKPVCMVRDGKTFYEG-DITFTDSCATCRCSKRKEICSGVKC--------------- 1718
..|| |:|. |..:||..:..| .:...::|.:|.|:. ||::|
Human 1212 MKCV--AQCG--CYDKDGNYYDVGARVPTAENCQSCNCTP-----SGIQCAHSLEACTCTYEDRT 1267
Fly 1719 ----DV--PATTGLPAPLV----------------EGTTLPTPL--------------ATQNQTK 1747
|| ..|.||.|.|: .||...||. |....|.
Human 1268 YSYQDVIYNTTDGLGACLIAICGSNGTIIRKAVACPGTPATTPFTFTTAWVPHSTTSPALPVSTV 1332
Fly 1748 CVKGWTRWCDKDRDTSDKSVRLNDEEKVP-----RYDRMENV----YGTCLKQYMTKVECRVKDT 1803
||:...|| |...|.....| .::..||: |..| ..:..:|||....
Human 1333 CVREVCRW----------SSWYNGHRPEPGLGGGDFETFENLRQRGYQVC--PVLADIECRAAQL 1385
Fly 1804 HEAP-EQMDENVVCSLEEGLRCIGK------CHDYELRAFCQCD-------------------EE 1842
.:.| |::.:.|.|....||.|... |||||||..| |: ..
Human 1386 PDMPLEELGQQVDCDRMRGLMCANSQQSPPLCHDYELRVLC-CEYVPCGPSPAPGTSPQPSLSAS 1449
Fly 1843 LEPELPKP-----TEKPQLGL---------------ACDAAVVEYKEFPGDCHKFLHCQPKGVEG 1887
.||.:|.| |||..|.: :....|......||. ..|||:....
Human 1450 TEPAVPTPTQTTATEKTTLWVTPSIRSTAALTSQTGSSSGPVTVTPSAPGT----TTCQPRCQWT 1510
Fly 1888 GWI---Y---------VE-----KTCGEYMMFNPTMLICDHIATVTEIKPN-----CGLKPEPEP 1930
.|. | || :..|.::...|..:.|. .|..|| .|.|...:.
Human 1511 EWFDEDYPKSEQLGGDVESYDKIRAAGGHLCQQPKDIECQ-----AESFPNWTLAQVGQKVHCDV 1570
Fly 1931 EFEPIKQCPPGKIKSECANQCEN--------TCHYYGSILKKRGLCQVGEHCK-----PGCVDEL 1982
.|..: |.| .|:.| :.|.||...:||: |....||
Human 1571 HFGLV---------------CRNWEQEGVFKMCYNY----RIRVLCCSDDHCRGRATTPPPTTEL 1616
Fly 1983 RPDCPKLGK--FWRDEDTCVHADECPCMDKAEHYVQPHKPVLGEF----EVCQCIDNAFTCVPNK 2041
........: |...:.| ..|.:.:|........|.|.|. .....:..|.|..|..
Human 1617 ETATTTTTQALFSTPQPT-----SSPGLTRAPPASTTAVPTLSEGLTSPRYTSTLGTATTGGPTT 1676
Fly 2042 P----EP-VPKDEDDDLDLVSVV-----------PIYPVTLTPPLQ-------------CSPERL 2077
| || ||......|...|.: |..|.||.|... .|.|.|
Human 1677 PAGSTEPTVPGVATSTLPTRSALPGTTGSLGTWRPSQPPTLAPTTMATSRARPTGTASTASKEPL 1741
Fly 2078 IPKIENPAHSLPDSIFNASSQLA-PEHGPKMARLTKE---------QPRGSWSPSINDQMQYLEL 2132
...: |.:|...:..:.::.: |.....|:.||.. ||:..|: ::.::
Human 1742 TTSL---APTLTSELSTSQAETSTPRTETTMSPLTNTTTSQGTTRCQPKCEWT-------EWFDV 1796
Fly 2133 NFAKPEPFYGVVMAGSPEFDN 2153
:| |..||.......|:|
Human 1797 DF----PTSGVAGGDMETFEN 1813
| 
