Protein Alignment Hml and vwf

DIOPT Version :10

• Sequence 1: NP_524060.2
• Gene: Hml / 39529
• FlyBaseID: FBgn0029167
• Length: 3843
• Species: Drosophila melanogaster
• Sequence 2: NP_001268918.1
• Gene: vwf / 570643
• ZFINID: ZDB-GENE-070103-1
• Length: 2812
• Species: Danio rerio
• Alignment Length: 3628
• Identity: 803/3628 - (22%)
• Similarity: 1293/3628 - (35%)
• Gaps: 1087/3628 - (29%)

  Fly   452 WSSEETVVTMSSYSLYQSNNLDIVIDKTPRPALCTTWGGINMKTFDGLVFKAPLSCSHTLITDKV 516
            ||....:|.::...|       ::::.:.|   |:.:...::.||||::::.|..||:.|..|..
Zfish     6 WSRIMWIVILNLSDL-------LLVEGSAR---CSLFSRQHIHTFDGVIYEFPGDCSYMLAGDCR 60

  Fly   517 SGTFDIILKACPYGSGYGCAHTLKILWQSVLYTFENLNGTMQLTTPIKKLPMPVQVMGMKVMPVA 581
            ..:|. ||....:|...|....|..:::..|    :::||  |:...::||:|.....:......
Zfish    61 QRSFS-ILGDFSHGKRKGVTVFLGEMFELHL----SVDGT--LSQGAERLPLPYASSSVFAGYEL 118

  Fly   582 QHVQIDLESVGLKLDWDHRQYVSVQAGPQMWGKVGGLCGTLDGDPNTDLTSRTGKKLATVKAFAD 646
            .:|::..|..|..:..|....:.:....:...:..||||..:.....:.:::.|........||:
Zfish   119 GYVRLWSEEFGFSIRIDPLHNIQLTLEKRHSNQTCGLCGNYNYLAEDEYSAQEGFLTDDPYDFAN 183

  Fly   647 AWRVEDRSELCQVENSAEMEFGMDSC----EQSKLQKAVSVCERLLANEKLGDCIKPFNYDALIR 707
            :|.::...|.|:     .:.....||    |.:|.|  :|.||.:.::.....|....:..|.:.
Zfish   184 SWAMKGADEPCK-----RVLPPSQSCNSTGESTKDQ--MSACESMRSSVLFMHCAHLVDPAAFVS 241

  Fly   708 TCMADYCNC-ANREHPESCNCDAIAMLAKECAFKGIKLEHGWRNLEICPISCGFGRVYQACGPNV 771
            .|.:|.|:| |.:|    |.|.|:...::.||.:||.|.: |.....|...|..|..|..|.|..
Zfish   242 VCESDVCHCSAGKE----CVCQAMLEYSRACASRGITLSN-WHTQSQCSPKCPVGMEYSDCTPTC 301

  Fly   772 EPTCDSDLALPASKGACNEGCFCPEGTVQYKEACITRELCPCSLRGKEFKPESTVKKNCNTCTCK 836
            ..:|.:.......|..|.:||.||.|.|...:.|:....|.|:..|:.:.|.|.:.::||||.|:
Zfish   302 STSCQNVNIQEVCKEECVDGCICPAGKVLDGDRCVDVSQCSCTHAGRRYPPASYISQDCNTCVCR 366

  Fly   837 NGQWRCTEDKCGARCGAVGDPHYQTFDGKRYDFMGKCSYHLLK-TQNTSVEAENVACSGAVSESM 900
            :|.|.||.:.|...|...|..||:|||.|.:.|.|.|.|.|.| .|:.|.        .||.|:.
Zfish   367 HGSWECTNEGCPGECLVTGQSHYKTFDNKFFTFSGICHYLLAKDCQSNSF--------SAVIETA 423

  Fly   901 NFAAPDDPSCTKAVTIRFILRDGTPSVIKLDQGLTTIVNDKPIAKLPKMLGLGEVLIRRASSTFL 965
            ..|...|..||:::|:||  :|.....:.|..|....|:...: :.|  |..|.:.|:....:.:
Zfish   424 QCADDQDAICTRSITLRF--KDLANQTVHLKHGGVVSVDGMDV-QTP--LINGPLRIQNTVLSSV 483

  Fly   966 TVEFADGIRVWWDGVSRVYIDAPPSLRGQTQGLCGTFNSNTQDDFLTPEGDVETAVEPFADKWRT 1030
            .:.:...:.:.|||..||.:...|:..||..||||.:|.|..|||||..|.|||.||.|.:.|:.
Zfish   484 RLRYGHDLHLDWDGRGRVLLRLKPAYAGQMCGLCGNYNGNQGDDFLTVGGLVETRVEAFGNSWKM 548

  Fly  1031 KDTCQFKAETHQGPHPCTLNPEKKAQAEKFCDWILQDIFQDCHFLVEPEQFYEDCLYDTCACKDE 1095
            ...|.  ....|...||:|||::...||:.|..:|...|:.||::|.||.:.::|.||.|||.|.
Zfish   549 NADCD--DVQMQNSDPCSLNPKRVRFAEEACAVLLSMKFEPCHYMVNPEPYVKNCRYDVCACADG 611

  Fly  1096 MSKCFCPILSAYGTECMRQGVKTGWRMSVKECAVKCPLGQVFDECGDGCALSCD--DLPSKGSCK 1158
             .:|.|..:|:|...|..:||...|| |...|.:.||..||::.||..|..:|.  .||..| |.
Zfish   612 -QECLCDAVSSYAVACAARGVLVNWR-SHGYCELTCPDAQVYEMCGSVCNQTCRSLSLPDTG-CD 673

  Fly  1159 RECVEGCRCPHGEYVNEDGECVPKKMCHCNFDGMSFRPGYKEVRPGEKFLD---LCTCTDGVWDC 1220
            ..|.|||.||.|.::::.|||||.:.|.|:.:|..|       .|.:...|   :|.|..|...|
Zfish   674 GVCEEGCFCPRGLFLSDAGECVPPQHCSCHHNGEIF-------EPNDMIGDHHSICVCESGSMHC 731

  Fly  1221 QDAEPGDK-------DKYPPSSELRSKCAKQPYAEF---------TKCAPKEPKTCKNMDKYVAD 1269
            ...|....       |:..||...||.....|...|         .:||    |||:|::....
Zfish   732 TSNEATGSTLSDLFFDEQSPSRGRRSLSCPPPLQRFECESARDAGIECA----KTCQNLELDCV- 791

  Fly  1270 SSDCLPGCVCMEGYVYDTSRLACVLPANCSCHHAGKSYDDGEKIKEDCNLCECRAGNWKCSKNGC 1334
            |..|:.||:|..|.|  ..|..|:....|.|:|..:.|:.|:.|..|||.|.|....||||:..|
Zfish   792 SLGCVSGCMCPPGTV--RYRKDCIPQEQCPCYHNSRPYESGQSITVDCNTCVCEQRQWKCSERVC 854

  Fly  1335 ESTCSVWGDSHFTTFDGHDFDFQGACDYVLAKGVFDNGDG-FSITIQNVLCGTMGVTCSKSLEIA 1398
            :..|...||:|:.:|||..|.|.|.|.||||:...:..|| |.:.::|..||..|..||||:.:.
Zfish   855 DGVCRAIGDTHYISFDGLKFSFPGPCQYVLAQDYCNGLDGTFRVLVENSACGIAGYRCSKSITVL 919

  Fly  1399 LTG------HAEESLLLSADSAYSTDPNKTPIKKLRDSVNSKGHNAFHIYKAGVFVVVEVIPLKL 1457
            ..|      |.|..:             |.|:.|         .....|.::|::.:| ::...:
Zfish   920 YMGGLIVMEHGEVRM-------------KRPVLK---------ETEVEIVRSGLYYIV-LLGKHI 961

  Fly  1458 QVKWDEGTRVYVKLGNEWRQKVSGLCGNYNGNSLDDMQTPSMGLETSPMLFGHAWKLQPHCSAPV 1522
            .:.||.|||:.:::..::|.||.|||||::|:..:|:.:.|..:|.....||::||::|.|:..|
Zfish   962 SITWDTGTRISLQISGQYRGKVCGLCGNFDGSQNNDLLSSSNQMEVDAADFGNSWKVRPSCADAV 1026

  Fly  1523 APIDACKKHPERETWAQLKCGALKSDLFKECHAEVPLERFWKRCIFDTCACDQGGDCECLCTAVA 1587
            :.:..|.....:....:..|..|.|.:|::|::.|..|.:|..|..|||:|...|||.|.|..:|
Zfish  1027 SVVSQCSTDLVKLVTVEQSCRVLTSAIFRDCNSVVDPEPYWDICTQDTCSCPSVGDCACFCNTIA 1091

  Fly  1588 AYADACAQKGINIRWRSQHFCPMQCDP-------HCS-DYKACTPACAVETCDNFLDQGIAERMC 1644
            |||..|||||:.:.|||...||:.|:.       .|. .|..|..||. .||.:      .|.:.
Zfish  1092 AYAHECAQKGLPVNWRSNDLCPLSCEDLNKESGVQCEWRYNTCASACP-STCQH------PEPLS 1149

  Fly  1645 NRENCLEGCHIKPCEDGFIYLNDTYRDCVPKAECKPVCMVRDGKTFYEGD---ITFTDS--CATC 1704
            ...:|:|||| ..|..|.: |::..|.||..::|: || |.||:....|.   :...|.  |..|
Zfish  1150 CPISCVEGCH-AVCPPGHL-LDEVLRKCVEPSQCQ-VC-VHDGQRVSHGKQFILNHEDPRLCQIC 1210

  Fly  1705 RCSKRKEICSGVKCDVPATTGLPAPLVEGTTLPTPLATQNQTKCVKGWTRWCDKDRDTS---DKS 1766
            .|......|.  .|.|   |||.:.|...|..||||..........     ||:..|.:   |.|
Zfish  1211 HCESNTLTCG--PCPV---TGLTSTLAPTTVTPTPLPFSTPVPADA-----CDRAMDLAFLVDGS 1265

  Fly  1767 VRLNDEE---------KVPRYDRMEN--------VYGTCLKQYMTKVECRVKDTHEAPEQMDENV 1814
            ..|::::         :|....||.:        ::.:.:|.|..:|:..:........:.....
Zfish  1266 SALSEDDFSMIKLFILRVVERFRMGSAHTRATVLLFHSGVKSYDMQVQKWIFKKMVREMRYTGGD 1330

  Fly  1815 VCSLEEGLRCIGKCHDYE-------------LRAFCQCDEELEPELPKPTEKPQ----------- 1855
            |..::|.::.:. .:.|:             |.|...         |:|....|
Zfish  1331 VAFMDEAIKYLA-VYIYDKNKREHAGRVAILLTASAN---------PRPMRSTQRLLRKKDITIL 1385

  Fly  1856 -LGLACDAAVVEYKEFPGDCHKFLHCQPKGVEGGWIYVEKTCGEYMMFNPTMLICDHIATVTEIK 1919
             :.|..|..:.:..|.           .|.......||..:..|  :.:..:.|.|::.|:
Zfish  1386 TVALGPDVNMAQVNEI-----------TKATPSSRAYVVSSVTE--LDDEALSITDYLCTL---- 1433

  Fly  1920 PNCGLKPEPEPEFEPIKQCPPGKIKSECANQCENTCHYYGSILKKRGLCQVGEHCKPGCVDELRP 1984
               ||.|||:.:       ||                                ..||....
Zfish  1434 ---GLDPEPQKK-------PP--------------------------------TAKPSTTS---- 1452

  Fly  1985 DCPKLGKFWRDEDTCVHADECPCMDKAEHYVQPHKPVLGEFEVCQCIDNAFTCVPNKPEPVPKDE 2049
                                          |.|             ..||.|.:...|
Zfish  1453 ------------------------------VTP-------------TTNAITKLTIPP------- 1467

  Fly  2050 DDDLDLVSVVPIYPVTLTP-----PLQCSPERLIPKIENP-------AHSLPDSIFNASSQLAPE 2102
                 ..::|..:|...||     |...:...|:..:||.       .:...||:.|..:.|..:
Zfish  1468 -----TAAIVTAFPSIPTPGTTLVPTTVTTYDLVFLLENANATGEDGFNKTRDSLINIITSLDQK 1527

  Fly  2103 HGPKMARLTKEQPRGSWSPSINDQMQYLELNFAKPEPFYGVVM--------------AGSPEFDN 2153
            ....: |:|...    :|.::..::..:||:..:.     ||.              .|......
Zfish  1528 EAENL-RITVMM----YSVTVTVEISRMELHHREQ-----VVQRMRQLRWTEGAEVNTGHAVQSV 1582

  Fly  2154 YVTLFKILHSHDGIAYHYLVDETEKPQMFNGPLDSRAPVQTLFKIPIEASSLRIYPLKWHGSIAM 2218
            |.|:....||           :|....:|   |.:::|...:.:.|..::..:|||:    .|..
Zfish  1583 YETITTDTHS-----------DTPDQLVF---LITQSPPTDVIQRPPSSTHKKIYPI----GIGR 1629

  Fly  2219 RVE-----LLICGDK----EEPKPVPTVSTILPITERPARLVDLECIDLMGVDEGKMYQDQVQSS 2274
            ::.     ||...||    ::|..:.|:..:|....|..|...|..:.              ..:
Zfish  1630 KIRYEDLALLSFPDKPIMLDDPSDLRTLQPMLINISRTVRRPLLPTLP--------------PRA 1680

  Fly  2275 SLWQQPNLGKKLQLLELLKLSTPLAWRPLANSQNEFIEFDFLEPRNISGFVTKGGPDGWVTGYKV 2339
            :|.......|.:.:|.||:.|:...:..|    ..|:: .|::..||      |..|   |...|
Zfish  1681 TLPPSVPCSKPMDVLFLLRASSGSQFEDL----KTFVK-TFIKSTNI------GRND---TQVAV 1731

  Fly  2340 MFSKKKP----TWNTVLSTDGQARIFEANHDAETERRHHFKNPILTQYIK--------------- 2385
            |....|.    ||....:.|...::.|:.| .:|:.:     |.|...::
Zfish  1732 MVYGAKSAVAVTWRDEQTQDNLLKLLESLH-GKTDNQ-----PRLGAALRLAVQTAVSSTSGARM 1790

  Fly  2386 -----IVPAYWEKNIN-------------MRIEPLGCFLPYPEIQRQVPVEESKPTKCNICDGVS 2432
                 :|....:::|:             :.:.|:|....|.:|:                  |:
Zfish  1791 GIPKAVVMVVTDRSIDSVQEAANEALTAGVSVFPIGLGKQYDQIE------------------VN 1837

  Fly  2433 TSSSTTGCQCQDQLFWDGNTCVQHNLCPCIENYVSYPIGSKFENSACEDCVCVLGGHKNCKPKKC 2497
            |   ..|.|.|:.:...|:|              .|.:.....:.:..|.:|..|     .|..|
Zfish  1838 T---LAGPQAQENVILLGST--------------EYLLSMAAFDQSFPDKLCRAG-----PPGVC 1880

  Fly  2498 PPCLGGKLRPVITSDCFCKCEPCPKHQRLCPSSGDCIPEILWCNGVQDCADDEDASCSDSFTVEP 2562
            ....|.:.:|   .:.:...:.|  |..||..||                         :.|::.
Zfish  1881 VDDEGNERKP---GETWMLADGC--HSVLCNPSG-------------------------TITMQS 1915

  Fly  2563 D-VSREKNETEVITCPVPVCPPQMKIRITEKKSRKMSKMFTFSKQVSIVDDGTTITKTKFISSKE 2626
            . ::.||.|.       |||                                           |.
Zfish  1916 HRINCEKMEP-------PVC-------------------------------------------KN 1930

  Fly  2627 QILAMPNRELDFQLEEQCDEFTCVPIPSKQVDKNETVTCTEPKCPEKYDVELDMSASKVGDCLRY 2691
            .:.|:       :....|.                   ||. .||
Zfish  1931 NLPAL-------RYNHHCG-------------------CTW-TCP-------------------- 1948

  Fly  2692 SCVLRPNKDDVCEISGKS---FTTFDGTVFKY-GPCSHILARDIHSSSWSISVH-QQCSDETRKV 2751
                       |...|.|   ..:|.|...|. ..||::|.|   |....:.:| ..|.....::
Zfish  1949 -----------CSCMGSSTSHVVSFSGAALKVKSACSYLLLR---SGGAELVLHTTACQSSPNQI 1999

  Fly  2752 CHKVITIQDTEAGNELILLPHLKLKFNGYEFTVQQLINSPICKASFVVSQPGKTLLAV-STKYGF 2815
            |.|.:.::  |.|..::|...:|:...|.      |...|.......|:|.|..|..: |.::||
Zfish  2000 CMKSLELR--EGGTSVVLQDDMKVTVGGV------LTAVPFRTERVTVTQIGSILHQLRSEQHGF 2056

  Fly  2816 WVQLDDIGIVKVGISSKFIRTVD--------GLCGYYNGNQKDDKRSPDGQIIPNTEKFGDSWYD 2872
            .:..       ...|::|:..:|        ||||..:.:|.....| ||.:..:.:.:..:|
Zfish  2057 TLTF-------TPHSNEFMLNMDIAMKPNTTGLCGSCSDDQSGLLLS-DGSVTTDPDVYLQAW-- 2111

  Fly  2873 KRIPKDQCGDLK----CPREMQAKALQLCNIIHHPTFARCHKAVNYKQFLNNYCLEAACNCMMAN 2933
              ....:|...:    ||..::    :.|:::....|:.||..|..:.:: ..|...||
Zfish  2112 --ALGSECVQHQEIQLCPAGLE----KACDVLSSEVFSHCHALVPVQDYI-QICRSVAC------ 2163

  Fly  2934 NGDPAACKCNILESFVKKCLSVNPLVQLTTWRAVAQCEINCPSPLVHTDCYKRRCEPSCD----- 2993
              .|.|. |:::.::...|......|.   ||..:.|.::|...:.:..| :..|...|.
Zfish  2164 --QPNAL-CDLVTAYSTVCRQQGVCVD---WRTSSLCPMSCSDSMEYAAC-RSGCLEQCGQSQFT 2221

  Fly  2994 ----------NVHGDDCPVLPDACFPGCYCPEGTVRKGPNCVPISECKDCVCNSLGASKYMTYDR 3048
                      ..:|..|...|.   .||:||||:|.....||....|..||.:|....::|
Zfish  2222 PGDMMGDGLLKANGSVCLNTPT---EGCFCPEGSVLMEDKCVDREACSQCVEHSGKTHQFM---- 2279

  Fly  3049 KSFSFNGN-CTYLLSRD------VVLPGVHTFQVYVSMDDCKKLGQPTPVEGGSCAKSLHILNGD 3106
            :|::...| |...:..|      ..||             |.....|   |.|.|
Zfish  2280 ESWNPEDNPCVLCVCLDQQRINCTALP-------------CTNAKAP---ECGQC---------- 2318

  Fly  3107 HVIHVQRVPQKPKSLQVLVDGFEVKKIPYKDSWISLRQVVGKELVLSLPESHVELTASFEDLIFS 3171
                           :||.:
Zfish  2319 ---------------EVLQE--------------------------------------------- 2323

  Fly  3172 LGVPSIKYGSK----MEGLCGDCNGNAGNDLQPNPAKKKAGVDVIQSWQADEPKLGLVEECLSED 3232
                  |.|||    .|.:| |.|..     :|:|.....|:.|:.:...|
Zfish  2324 ------KMGSKCCPQYECVC-DINCK-----RPDPPHCDHGLSVVLTNPGD-------------- 2362

  Fly  3233 VPKEHCIPLPPEKDPCLQFYNAELFGKCPLAVDPIAYVSACQQDICKPGNTQQGVCVA---LAAY 3294
                 |:|:                           |...|::|.| |.:|:.. |.|   |:..
Zfish  2363 -----CLPV---------------------------YQCVCKKDQC-PDSTKPS-CPAYKKLSVK 2393

  Fly  3295 AKECNQHGICTNWRRPQLCPYECPSDMVYEPCGCAKNCDTIKALSEFDAVSLKNEAVVHTVKTDE 3359
            |.||     |.:::                   |..||..|                   .:|
Zfish  2394 ASEC-----CDSYQ-------------------CLCNCQNI-------------------TRT-- 2413

  Fly  3360 MCLSSERFEGCFCPPGKV----MDGGQCVPEIACTK---C--DDGLHLPDEKWKKDKCTECQC-- 3413
                        ||||.:    .:..||. |:.||.   |  |..::....:| ::||..|:|
Zfish  2414 ------------CPPGYITKTSTNDCQCT-EVTCTPDKVCVVDAVVYQVGSRW-EEKCKTCRCTE 2464

  Fly  3414 DSKGKT-----TCVEKKCQVEENICAEG--YRPETIVSVDECCPRYRCVPETKDPSKLCLAPLVP 3471
            .:.|:|     .||:..|   ..||..|  |..    |..|||
Zfish  2465 QTDGQTGLHIAQCVDPVC---NQICPVGSTYSH----SGGECC---------------------- 2500

  Fly  3472 ICGPGQFKKEKKDVNGCSQYICE--CIPKDQC---EIIELRELLPGEIIVNVEEGCCPTQKIECK 3531
                |..:|...:..|..:.:.|  ....|:|   |.:::.|    |:.:.       ...:.|.
Zfish  2501 ----GHCRKSSCEEGGLLRQVGEQWVSANDRCVWSECVQVNE----EVFIQ-------HTNVSCH 2550

  Fly  3532 PETCPKAPVNCQERFYEVKTIKEPGMCCSKHSCVPPKDLCIV---------QYELDEATKFTKTV 3587
            ....|..|:..:   .:..|:.:   ||....|| |.:.|::         :..||..| ..:.|
Zfish  2551 HMDTPACPLGTE---LQCNTVDD---CCPSCHCV-PMNACVLNQTVIAAGERVMLDVCT-HCECV 2607

  Fly  3588 GDKWTHAKEVCKQETCSYGPDGNAQVVSTLEQCLTDCAPGFSYQNLDKTKCCGKCVQTSCIFEQ- 3651
            |||.:: :..|::.:||                  .|:.|::.:.:... |||:||.|:|...:
Zfish  2608 GDKRSY-RLSCRKMSCS------------------PCSEGYTMEPIPNA-CCGRCVATACSVRRP 2652

  Fly  3652 --KLYEVNALWKSADNCTTYSC-LKKDGQFLVTTSREVCP--DVGSCLSH--LLYQ--DGCCKRC 3707
              :|..:.|.....|.||.::| :.||.:.::.|....||  |..|||.|  .:.|  |.||..|
Zfish  2653 DGELITLKANTTRTDGCTKHTCSVNKDEELVLETLVTTCPPFDRKSCLEHGGKISQIGDTCCNMC 2717

  Fly  3708 KSEPLVEDKSSCLPVSLAESRTKEILKFPVQGHGTCVNADPIQG-----FTDCEGACSSGSKYNT 3767
             :||      .|       .||..:|.:        :..|..|.     .|.|||.|.|.|.|:.
Zfish  2718 -TEP------EC-------RRTVGLLNY--------IRVDDCQSEEKIELTYCEGKCGSKSVYSL 2760

  Fly  3768 LTDMHEKFCTCCSIKSYHPISVKMICDDGHTFTQKHE---VPSNCGC--SPCS 3815
            .....|..|.|||.....|::|.:.|.:|   ||.|.   ..:.|.|  ..||
Zfish  2761 EKHKVENECVCCSATGTVPMNVSLRCANG---TQTHHQVLAVTGCDCMSHTCS 2810

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hml	NP_524060.2	VWD	485..636	CDD:459671	31/150 (21%)
		C8	684..754	CDD:462584	19/70 (27%)
		TIL	758..811	CDD:410995	15/52 (29%)
		VWD	840..1015	CDD:214566	57/175 (33%)
		C8	1054..1121	CDD:214843	24/66 (36%)
		TIL	1131..1185	CDD:410995	24/55 (44%)
		TIL	1245..1298	CDD:460351	17/61 (28%)
		VWD	1327..1498	CDD:214566	55/177 (31%)
		C8	1535..1609	CDD:214843	30/73 (41%)
		TIL	1938..2005	CDD:473303	4/66 (6%)
		FA58C	2089..2223	CDD:238014	25/152 (16%)
		FA58C	<2299..2403	CDD:238014	22/140 (16%)
		VWD	2703..2858	CDD:459671	39/168 (23%)
		TIL	2974..3030	CDD:460351	16/70 (23%)
		VWD	3035..3198	CDD:459671	23/173 (13%)
		C8	3248..3313	CDD:462584	13/67 (19%)
		VWC	3397..3451	CDD:450195	18/62 (29%)
		GHB_like	<3755..3813	CDD:473907	21/62 (34%)
vwf	NP_001268918.1	VWD	29..167	CDD:459671	31/144 (22%)
		C8	218..284	CDD:462584	19/70 (27%)
		TIL	288..341	CDD:410995	15/52 (29%)
		VWC	343..>387	CDD:450195	16/43 (37%)
		VWD	381..530	CDD:459671	51/161 (32%)
		C8	572..641	CDD:214843	27/70 (39%)
		TIL	645..700	CDD:410995	24/55 (44%)
		TIL	760..818	CDD:410995	17/64 (27%)
		VWD	847..1003	CDD:214566	55/178 (31%)
		C8	1043..1113	CDD:214843	30/69 (43%)
		TIL	1131..1181	CDD:410995	18/58 (31%)
		VWA_N2	1183..>1228	CDD:465038	15/50 (30%)
		VWA	1257..1421	CDD:459670	25/186 (13%)
		vWFA_subfamily_ECM	1493..1628	CDD:238727	27/162 (17%)
		VWA	1693..1848	CDD:459670	34/195 (17%)
		VWD	1939..2091	CDD:214566	41/220 (19%)
		C8	2131..2195	CDD:214843	15/80 (19%)
		CT	2731..2808	CDD:214482	24/87 (28%)