DRSC/TRiP Functional Genomics Resources

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Protein Alignment Hml and irg-5

DIOPT Version :9

Sequence 1:NP_524060.2 Gene:Hml / 39529 FlyBaseID:FBgn0029167 Length:3843 Species:Drosophila melanogaster
Sequence 2:NP_001366887.1 Gene:irg-5 / 185307 WormBaseID:WBGene00009429 Length:343 Species:Caenorhabditis elegans


Alignment Length:222 Identity:47/222 - (21%)
Similarity:80/222 - (36%) Gaps:65/222 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly   371 IDIEYKCNYLQ-----GQYLPAPLPKCIFPPGYTVRSTSSMQGVTHQNGVYHRGMSGEMAYE--- 427
            :||.   ||.|     |.:....|....|.   |||:.::.| |..:.|....|...|..|:   
 Worm   124 VDIS---NYQQVIKATGTFFNTTLEANKFT---TVRAANNDQ-VALKYGSRETGFHDETMYQTFV 181

  Fly   428 ------LQTERQKLLALLAKYRDLERRSEW--WSSEETVVTMSSY-----SLYQSNNLDIVIDKT 479
                  :.:|      .|.:|.||....::  :|:..|:..::.|     ||:.||:...|....
 Worm   182 FDGNDFMNSE------YLGRYTDLYHGPDYTAFSTSNTLTLLNLYRTPSDSLFISNDASAVKKYD 240

  Fly   480 PRPALCTTWGGINMKTFDGLV--FKAPLSCSHTLITDKVSGTFDIILKACPYGSGYGCAHTLKIL 542
            ....|..:    :.....||:  |.......:|:|.|   |...|.:|:..:.:.|         
 Worm   241 QYKILVVS----SANQISGLMYNFHDNADAWYTIICD---GCNSINIKSLDFDTSY--------- 289

  Fly   543 WQSVLYTFENLNGTMQL--TTPIKKLP 567
                       ||.:::  .:|.:|||
 Worm   290 -----------NGYLEVQELSPTQKLP 305

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
HmlNP_524060.2 VWD 485..636 CDD:295339 16/87 (18%)
C8 680..754 CDD:285899
TIL 758..811 CDD:280072
VWD 840..1015 CDD:214566
C8 1054..1121 CDD:214843
TIL 1131..1185 CDD:280072
TIL 1245..1298 CDD:280072
VWD 1327..1498 CDD:214566
C8 1535..1609 CDD:214843
Mucin2_WxxW 1751..1837 CDD:290069
TIL 1938..2005 CDD:280072
FA58C 2089..2223 CDD:238014
FA58C 2104..2225 CDD:214572
FA58C <2299..2404 CDD:214572
FA58C <2299..2403 CDD:238014
VWD 2703..2858 CDD:295339
C8 2893..2970 CDD:285899
TIL 2974..3030 CDD:280072
VWD 3035..3198 CDD:295339
C8 3257..3313 CDD:285899
VWC 3397..3451 CDD:302663
GHB_like <3755..3813 CDD:304424
irg-5NP_001366887.1 CUB_2 17..127 CDD:280554 1/2 (50%)
BBS2_N <209..278 CDD:405471 16/75 (21%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1216
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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