DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Hml and LOC100536949

DIOPT Version :9

Sequence 1:	NP_524060.2	Gene:	Hml / 39529	FlyBaseID:	FBgn0029167	Length:	3843	Species:	Drosophila melanogaster
Sequence 2:	XP_021326445.1	Gene:	LOC100536949 / 100536949	-ID:	-	Length:	3362	Species:	Danio rerio

Alignment Length:	3904	Identity:	846/3904 - (21%)
Similarity:	1296/3904 - (33%)	Gaps:	1161/3904 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   474 IVIDKTPRP----ALCTTWGGINMKTFDGLVFKAPLSCSHTLITDKVSGTFDIILKAC--PYGSG 532
            ||.:..|.|    .:|:|||..:.|||||..|:.|.:||:.|:            |.|  |. |.
Zfish    57 IVTEAVPNPDHQSTICSTWGNFHFKTFDGHFFQLPDTCSYVLV------------KMCNSPV-SD 108

  Fly   533 YGCAHTLKILWQSVLYTFE----NLNGTMQLTTPIKKLPMPVQVM-------GMKVMPVAQHVQI 586
            :......:|:..|:  ||.    ||.||:.:.|. ..:.|..||:       |:.: .::.:|:|
Zfish   109 FNIEIQRQIVNNSI--TFGKITINLEGTVIVLTN-NDIIMGDQVVYDSTYKDGITI-ELSPNVKI 169

  Fly   587 DLESVGLKLDWDHRQYVSVQAGPQMWGKVGGLCGTLDGDPNTDLTSRTGKKLATVKAFADAWRVE 651
            . ...|:.:.|:..:...::...:...|..||||..:||.:.| ..:....|||       |: |
Zfish   170 S-NKHGVSVFWEKDRSFLIELSEKYKEKTCGLCGNFNGDKSDD-AFKNEYDLAT-------WK-E 224

  Fly   652 DRSELCQVENSAEMEFGMDSCEQSKLQKAVSVCERLLANEKLGDCIKPFNYDALIRTCMADYCNC 716
            ..||.|   ...||:.. ..||..     .|:|::.|::.....|....:..:..:.|.:|.|.|
Zfish   225 SSSESC---GHIEMQLN-GQCENQ-----TSLCQQYLSSPGFSGCYDVMDMSSFEKACESDLCQC 280

  Fly   717 ANREHPESCNCDAIAMLAKECAFKGIKLEHG----WRNLEICPISCGFGRVYQACGPNVEPTCDS 777
            ...   ..|.|:.:..::::|...|     |    ||..::||.:|....:|..||...:.||.:
Zfish   281 YGN---HDCLCNTLTEISQQCTHAG-----GQPGTWRTKQLCPKTCPLNLLYLECGGPCKSTCSA 337

  Fly   778 DLALPASKGACNEGCFCPEGTVQ---YKEACITRELCPCSLRGKEFKPESTVKKNCNTCTCKNGQ 839
            ..|.......|.:|||||||.|:   .:..|:....|||....|.:....:..:.|.||||..|.
Zfish   338 PTADLMCTDHCVDGCFCPEGMVEDDIGQSGCVPVNKCPCVHNNKTYFSGDSYTQACKTCTCDAGH 402

  Fly   840 WRCTEDKCGARCGAVGDPHYQTFDGKRYDFMGKCSYHLLKTQNTSVEAENVACSGAVSESMNFAA 904
            |.|:...|...|..||..|..|:|||.:.|.|.|.|.|.|..|.|    :.|..|.:       |
Zfish   403 WTCSYLDCPGICSVVGGSHVTTYDGKTFTFSGNCDYILTKHSNDS----DFAVVGNL-------A 456

  Fly   905 PDDPSCTK-----------AVTIRFILRDGTPSVIKLDQGLTTIVNDKPIAKLPKMLGLGEVLIR 958
            |.:|..|.           .:||.|           ...|..|:..:.|. .||.:  :|.|.|.
Zfish   457 PCNPDRTDICLNSVALVILGITISF-----------SSNGDVTLNGNSPF-NLPAI--IGPVSIF 507

  Fly   959 RASSTFLTVEF-ADGIRVWWDGVSRVYIDAPPSLRGQTQGLCGTFNSNTQDDFLTPEGDVETAVE 1022
            :.||:|:..:. :..:.:....:.::||.|....:|:..||||.:|...:|||.|..|.:|....
Zfish   508 QPSSSFVIADLHSIRLEIQLAPIMQLYIVASTEEKGKMTGLCGNYNDVQKDDFKTESGIIEGTST 572

  Fly  1023 PFADKWRTKDTCQFKAETHQG---PHPCTLNPEKKAQAEKFCDWILQD--IFQDCHFLVEPEQFY 1082
            .|.:.| .|:..|:.....:.   .:||:|..|.:..|:.:|..:...  :|..||..:.|:.:|
Zfish   573 TFVNYW-IKNNVQYSCTDVKDTFTENPCSLRIETEKLAKDWCSRLTNQSGVFSACHSEICPDIYY 636

  Fly  1083 EDCLYDTCACKDEMSKCFCPILSAYGTECMRQG-VKTGWRMSVKECAVK--CPLGQVFDECGDGC 1144
            :.|:||||.|.| :.:|.|..||.|...|..:| :..|| |..:.|..|  ||....:......|
Zfish   637 QWCVYDTCKCAD-IRQCMCAALSTYAHACAARGIILQGW-MDAEPCGEKTNCPDNMKYSYGVTSC 699

  Fly  1145 ALSCDDLP-SKGSCKREC--VEGCRCPHGEYVNEDGECVPKKMCHCNFDGMSFRPGYKEVRPGEK 1206
            ..:|..|. .:.:|:...  |:||.||.|.::||:..|||...|.|..|.....|.....:.|.|
Zfish   700 DSTCRSLSGQENTCQGSFTPVDGCVCPEGTFLNEEDRCVPADQCPCYLDDKVIHPSETISKDGVK 764

  Fly  1207 FLDLCTCTDGVWDC--QDAEPGDKDKYPPSSELRSKCAKQPYAEFTKCAPKE--------PKTCK 1261
                |||..|...|  ||.||                   |.. |..|:..|        ..||:
Zfish   765 ----CTCNLGKLQCSSQDCEP-------------------PMI-FFNCSNYEQDQKGLECQSTCE 805

  Fly  1262 NMDKYVADSSDCLPGCVCMEGYVYDTSRLACVLPANCSCHHAGKSYDDGEKIKEDCNLCECRAGN 1326
            ..|.....|:.|:.||:|.||.:.| ....||....|||.|.|.:|...|::::|||.|.|..|.
Zfish   806 KQDSNNCVSTGCVSGCMCPEGLLAD-GEGGCVASYECSCTHNGVTYKPMEQVQQDCNTCTCTNGM 869

  Fly  1327 WKCSKNGCESTCSVWGDSHFTTFDGHDFDFQGACDYVLAKG--VFDNGDGFSITIQNVLCGTMGV 1389
            |.|::..|..||:::|:.||.||||:.:.:.|.|.:.||..  ..|....|.:..:|.||.:...
Zfish   870 WICTEVSCYGTCTIYGEGHFKTFDGNRYSYHGDCAHTLAHDSCSMDQSPSFRLVSENKLCESTST 934

  Fly  1390 TCSKSLEIALTGHAEESLLLSADSAYSTDPNKTPIKKLRDSVNSKGHNAFHIYKAGVFVVVEVIP 1454
            .| ||:.:.........:.||.|.....:.:.|..|             :.|:.||:::||||..
Zfish   935 IC-KSISLFFGIQQPSEIHLSEDGVKVLESSNTEYK-------------YQIHSAGIYIVVEVQG 985

  Fly  1455 LKLQVKWDEGTRVYVKLGNEWRQKVSGLCGNYNGNSLDDMQTPSMGLETSPMLFGHAWKLQPHCS 1519
            | |.:.||:.|.|.::|....:..|.|||||::||:.:|....:..:.|.|..||.:||::|.|.
Zfish   986 L-LNLIWDKKTSVILQLHPNLKGNVCGLCGNFDGNANNDFMKHNGEVVTDPEKFGISWKVKPDCP 1049

  Fly  1520 APVAPIDACKKHPERETWAQLKCGALKSDLFKECHAEVPLERFWKRCIFDTCACDQGGDCECLCT 1584
            ......|.|.::|.|..|::.:|..:.||:||:||..|...:::..|..|||.|:.||||:|.||
Zfish  1050 DVTNIKDLCTENPHRSVWSEKRCSIIISDVFKDCHTLVDPNQYYDDCKRDTCGCETGGDCDCFCT 1114

  Fly  1585 AVAAYADACAQKGINIRWRSQHFCPMQCDPH-----CS-DYKACTPACAVETCDNFLDQGIAERM 1643
            ||||||..|.:||..::|||.:.||:.||.:     |. .|.:|.|.|. :||.|      ....
Zfish  1115 AVAAYAAECRRKGACVKWRSPNTCPLFCDYYNPPGKCEWHYDSCGPPCP-KTCKN------PTGT 1172

  Fly  1644 CNRE-NCLEGCHIKPCEDGFIYLNDTYRDCVPKAECKPVCMVRDGKTFYEGDITFT-----DSCA 1702
            |:.: ..|||| ...|.....||.|....||.:..|     :.:||.|..|...:|     .:||
Zfish  1173 CSDQIPFLEGC-FPQCPPETPYLLDETMTCVKECYC-----IYNGKQFTVGSKVYTIEYKEGTCA 1231

  Fly  1703 TCRCSKRKEICSGVKCDVP-----ATTGLPAP-------------LVEGTTLP-----TPLATQN 1744
            :..|.:...| ..:..|.|     .||.:|.|             :...||.|     |.:.|..
Zfish  1232 SGVCIENGAI-KNITMDCPTTTPSTTTTVPPPSTATEIFISTTPTVTTTTTTPTIPTITTIVTPP 1295

  Fly  1745 QTKCVKGWTRWCDKDRDTSDKSVRLNDEEKVPRYDRMENVYGTCLKQYMTKVE---CRVKDTHEA 1806
            .|........:......|:..::........|....||  ..|.:  :.|..|   ...|.|...
Zfish  1296 STTPEISTATFTTPTVTTTTPTIPTTTTTVTPPSTTME--MSTTI--FTTPTETTTISTKPTTTT 1356

  Fly  1807 PEQMDENVVCSLEEGLRCIGKCHDYELRAFCQCDEELEPELPKPTEKPQLGLACDAAVVEYKEFP 1871
            |                                 ....||:...|.....|......:
Zfish  1357 P---------------------------------PSTTPEISTVTSTTPTGTTATPTI------- 1381

  Fly  1872 GDCHKFLHCQPKGVEGGWIYVEKTCGEYMMFNPTMLICDHIATVTEIKPNCGLKPEPEPEFEPI- 1935
                      |....  .:....|..| :...||:.......|.|...|:..::........|.
Zfish  1382 ----------PTTTT--TVTPPSTTTE-ISTTPTVSTITPTITTTTTPPSTTIEISTATSTTPTV 1433

  Fly  1936 --------KQCPPGKIKSECANQCENT---------------------CHYYGSILKKRGLCQVG 1971
                    ....|....:|.::....|                     ||:          .:..
Zfish  1434 TTTTPTKSTTITPPSTTTETSSTIRTTSTVTITTPTISTTTITLTTPICHW----------SEWF 1488

  Fly  1972 EHCKPGCVDELRPDCPKLGKFWR-DEDTCVHADECPCM----DK---AEHYVQPHKPVLG---EF 2025
            ::.:|. .|....:...:.:.|: ::..|...|:..||    ||   .|::  .|..|:.   .|
Zfish  1489 DNSQPS-TDVEGQEIESIKELWQTNKIPCEIPDKIECMSNYGDKNYTGENW--NHDQVVSCNTSF 1550

  Fly  2026 E-VCQCIDNAFTCVPNKPEPV----------------------PKDEDDDLDLVSVVPIYPV--T 2065
            . :|..:|||:....|....|                      |..........|..|..|.  |
Zfish  1551 GLLCSNLDNAYEACDNHLIRVCCNGSLSTTSSTISTTSTTITPPSTTSVTSTTTSTTPTIPTTST 1615

  Fly  2066 LTPP----LQCSPERLIPKIENPAHSLPDSIFN-------------ASSQLAPEH---------- 2103
            :|||    :..:.....|.|...:...|.|..:             .:|.:.|..
Zfish  1616 ITPPSTTSVTSTTTSTTPTIPTTSTITPPSTTSVTSTTTFTTPTIPTTSTITPPSKTTVTSTTTF 1680

  Fly  2104 -GPKMARLTKEQPRGSWSPSINDQMQYLELNFAKPEPFYGVVMAGSPEFDNYVTLFKILHSHDGI 2167
             .|.:...|...|..:..||...::..:.          ...:.|:.......|
Zfish  1681 TTPTVTTTTPTIPTTTSPPSTTTELSTVT----------STTLTGTTATPTIPT----------- 1724

  Fly  2168 AYHYLVDETEKPQMFNGPLDSRAPVQTL------------FKIPIEASSLRIYPLKWHGSIAMRV 2220
                 ...|.:|......:.:...|.|:            ..|.|..::..|.|..
Zfish  1725 -----TSTTVRPPSTTTEISTTPTVSTITPTITTTTTPPSTTIEISTTTSTITPPS--------- 1775

  Fly  2221 ELLICGDKEEPKP-VPTVSTILPITERPARLVDLECIDLMGVDEGKMYQDQVQSSSLWQQPNLGK 2284
            ...:........| :||.|||.|    |::..                   |.|::.:..|.
Zfish  1776 TTSVTSTTTSTTPTIPTTSTITP----PSKTT-------------------VTSTTTFTTPT--- 1814

  Fly  2285 KLQLLELLKLSTPLAWRPLANS-QNEFIEFDFLEPRNISGFVTKGGPDGWVTGYKVMFSKKKPTW 2348
                   :..:||..  |...| .:...|...:....::|  |...|....|...|    :.|:.
Zfish  1815 -------VTTTTPTI--PTTTSPPSTTTELSTVTSTTLTG--TTATPTIPTTSTTV----RPPST 1864

  Fly  2349 NTVLSTDGQARIFEANHDAETERRHHFKNPILTQYIKIVPAYWEKNINMRIEPLGCFLPYPEIQR 2413
            .|.:||        |....:|...   ..|.:.....:.|......|:..|....
Zfish  1865 TTEIST--------ATSSTQTVTT---TTPTIPTITTLTPPTSTTEISTTISTTS---------- 1908

  Fly  2414 QVPVEESKPT--------KCNICD---GVSTSSSTTGCQCQD----QLFWDGN--TCVQHNLCPC 2461
              .|..|.||        ...|||   ....|..:|..:.|:    :..|:.|  .|...:...|
Zfish  1909 --TVTTSTPTISTTTITLTTPICDWSEWFDNSQPSTDVEGQEIESIKDLWETNKIPCEIPDKIEC 1971

  Fly  2462 IENY--VSYPIGSKFENSACEDCVCVLGGHKNCKPKKCPPCLGGKLRPVITSDCFCKCEPCPKHQ 2524
            :.||  .:| .|..:.:.....|....|                    ::.|:.....|.|..|.
Zfish  1972 MSNYGDKNY-TGENWNHDQVVSCNTSFG--------------------LLCSNLDNAYEACDNHL 2015

  Fly  2525 -RLCPSSGDCIPEILWCNGVQDCADDEDASCSDSFTVEPDVSREKNETEVITCPVP--------- 2579
             |:|            ||  ...:.......:.|.|:.|..:  ..||.:.|...|
Zfish  2016 IRVC------------CN--VSLSTTSSTMSTTSTTITPPST--TTETSITTSTTPTVSTTTRTI 2064

  Fly  2580 ------VCPPQMKIR--------------------ITEKKSRKMSKMFTFSKQVSIVDDGT---- 2614
                  |.||.....                    .|...|...:::.|.:.....|...|
Zfish  2065 PTTTTTVTPPSTTTETSTTTTPTVTTTTPTISTAITTTTPSSTTTEISTATSTTPTVTTTTPTIP 2129

  Fly  2615 ------TITKTKFISSKEQILAMPNRELDFQLEEQCDEFTCVPIPSKQVDKNETVTCTEPKCPEK 2673
                  |.|:|...||....:....|.:..........||...| |.......|||.|.|..|
Zfish  2130 TTSPPSTTTETSTASSITPTVTTTTRTIPTTTSTVTPPFTTTEI-STAASTTYTVTTTTPTIP-- 2191

  Fly  2674 YDVELDMSASKVGDCLRYSCVLRPNKDDVCEISGKSFTTFDGTVFKYGPCSHILARDIHSSSWSI 2738
                              :...||:  ...|||..:.||  .||....|....:......|:...
Zfish  2192 ------------------TTTTRPS--TTTEISTATSTT--PTVTTTTPTIPTITTSTPPSTTQE 2234

  Fly  2739 SVHQQCSDETRKVCHKVITIQDTEAGNELILLPHLKLKFNGYEFTVQQ-LINSPICKASFVVSQP 2802
            :.....:..|.|.....|....|     .:..|....:.:....|..: ...:|....:.....|
Zfish  2235 TYTTTSTTPTVKTTTPTIPTTPT-----TVTPPSTTTEISTATSTTSKGTTTAPTIPTNTTAVTP 2294

  Fly  2803 GKTLLAVSTKYGFWVQLDDIGIVKVGISSKFIRTVDGLCGYYNGNQKDDKRSPDGQIIPNTEKFG 2867
            ..|..|.:..:          ||                  |.|.......||
Zfish  2295 PSTTTATTPAF----------IV------------------YTGPPPTPSPSP------------ 2319

  Fly  2868 DSWYDKRIPKDQCGDLKCPREMQAKALQLCNIIHHPTFARCHKAVNYKQFLNNYCLEAACNCMMA 2932
                   :|                                       |.||.......|.|:..
Zfish  2320 -------MP---------------------------------------QQLNTTTTTTTCFCIYN 2338

  Fly  2933 NNGDPAACKCNILESFVKKCLSVNPLVQLTTWRAVAQCEINCPSPLVHTDCYKRRCEPSC----- 2992
            |...||....|:|:.                                   ||...|..||
Zfish  2339 NVKYPAGSTFNLLDK-----------------------------------CYSAYCNSSCSVVQQ 2368

  Fly  2993 ---DNVHGDDCPVLPDACFPGCYCPEGTVRKG---------PNCV----PIS-----------EC 3030
               ||...|.|.:..        |..|||...         |.||    |:.           ||
Zfish  2369 INFDNSTTDACTIKT--------CKNGTVTSNHVQCDPVVVPKCVNGLGPVKVYYNNRCCYKYEC 2425

  Fly  3031 KDCVCNSLGASKYMTYDRKSFSFNGNCTYLLSRDVVLPGVHTFQVYVSM-----DDCKKLGQPTP 3090
             ||:|.:.|...|.::|.:.::|:|||||:|..::    :.|:.:.|.:     |..|::
Zfish  2426 -DCLCKAYGDPHYRSFDGQYYTFHGNCTYVLMEEI----IPTYNISVHLKNYYCDVVKRI----- 2480

  Fly  3091 VEGGSCAK-------SLHIL---NGDHVIHVQRVPQKPKSLQVLVDGFEVKKIPYKDSWISLRQV 3145
                :|.:       |..||   ..|.|:||.      .:.||.:           .::|:.|.:
Zfish  2481 ----ACTQYAIVYYNSYKILLNSTDDKVVHVY------VNNQVTI-----------PTYITDRFI 2524

  Fly  3146 V---GKELVLSLPESHVELTASFEDLIFSLGVPSIKYGSKMEGLCGDCNGNAGNDLQ-PNPAKKK 3206
            :   |....:::.:.:|::|.|..::  |:.:|...:.:..:|.||.|:.|..||.| ||.....
Zfish  2525 ITTTGIAATVNITDVNVQITVSATEV--SIRLPFSSFRNNTKGQCGCCDNNNTNDCQYPNGTINS 2587

  Fly  3207 AGVDVIQSWQADEPKLGLVEECL---SEDVPKEHCIPLPPEKDPCLQFYNAELFGKCPLAVDPIA 3268
            ........|.|        .||.   |..||     |:||...|| :...:.:|..|...|..:.
Zfish  2588 LCEKTAAFWNA--------SECTPPPSPPVP-----PIPPVVPPC-EILRSNVFKSCHDVVPFVE 2638

  Fly  3269 YVSACQQDICKPGNTQQGVCVALAAYAKECNQHGICTNWR-RPQ---LCPYECPSDMVYEPCG-- 3327
            |..||:.|:...||...| |.::.:||:.|.:..||.:|| .|:   ||.::|||..||:.||
Zfish  2639 YYQACKYDVTTMGNESYG-CASVESYAQLCGRKSICVDWRSSPELKGLCDFKCPSTKVYKACGPK 2702

  Fly  3328 CAKNCDTIKALSEFDAVSLKNEAVVHTVKTDEMCLSSE----RFEGCFCPPGKV---MDGGQCVP 3385
            ..|:|.|                ..:|:..|..|.|::    ..|||:||.|:.   :....|..
Zfish  2703 VEKSCST----------------SYNTMYADTQCQSNDCNQTLAEGCYCPDGQYRVNLASNLCTA 2751

  Fly  3386 EIACTKCDDGLHLPDEKWKKDKCTECQCDSKGKTTCVEKKCQVEENICAEGYRPETIVSVDECCP 3450
            ...|...|.....|.|.|.. :|....|.:.|....|...|.. .|:|.:||:.    :|:.|||
Zfish  2752 YCDCIGPDGSPRKPGEIWTY-QCYNYTCLNTGVYVKVPVTCPT-VNMCGDGYKS----AVENCCP 2810

  Fly  3451 RYRCVPETKDPSKL--------------CLAPLV------------------------------- 3470
            ...|..|.....|.              |..|.|
Zfish  2811 TCVCDYEQCLQKKCDVGFELGFNKTEGSCCPPCVQKDVCVYNNTEYKVGVYYFTCQTLNCRQVNG 2875

  Fly  3471 -----------PI-----CGPG-QFKKEKKDVNG-CSQ---------------------YICECI 3496
                       |.     ||.| ::.|::.|..| |.|                     |.||.:
Zfish  2876 SFVAEMTTTQCPYLSSQDCGSGFEYVKQEGDCCGACVQRNCTYMIENTTYTLQVGEVHSYKCENV 2940

  Fly  3497 P-------------KDQCEIIELRELLPGEIIVNVEEGCCPT----------------------Q 3526
            .             .::|..:...:..||...|..|..||.|                      .
Zfish  2941 TCSAISGSPVTERNSEKCTYLSSLDCKPGFEYVYQEGDCCGTCVQRNCTYMVDETTHTLQVGEVH 3005

  Fly  3527 KIECKPETC---PKAPVNCQERFYEVKT--------------IKEPGMCCSKHSCVPPKDLCIVQ 3574
            ..:|:..||   ..:||.  ||..|..|              |:| |.||.  :||...  |  .
Zfish  3006 SFKCENVTCSVISGSPVT--ERNSEKCTYLSSLDCKLGSEYMIQE-GDCCG--TCVQKN--C--T 3061

  Fly  3575 YELDEATKFTKTVGDKWTHAKE------------------------------------------- 3596
            |.:|..| :|..||:.:::..|
Zfish  3062 YMMDNTT-YTLQVGEVYSYKCENVTCSLISGSPVTERNSEKCTYLSSLDCKLGSEYVIKEGDCCG 3125

  Fly  3597 VCKQETCSYGPD------------------------GNAQVVSTLEQCL----TDCAPGFSYQNL 3633
            .|.|..|:|..|                        |:.......|:|.    .||.|.|.|..
Zfish  3126 TCVQRNCTYIMDNTTYTLQVGEVHSYKCENVTCSVSGSPVTERNSEKCTYLSSLDCKPFFEYVK- 3189

  Fly  3634 DKTKCCGKCVQTSCIFEQKLYEVNALWKS---ADNCTTYSCLKKDGQFLVTTSREVCP------- 3688
            .:..|||.|.||.||:|......:.|..:   ...|.|.:|.:.:|.|....:.:.||
Zfish  3190 QEGDCCGTCKQTCCIYEAPDNTTHTLKNNEAYTSKCETGTCHEVNGLFETEKTIKQCPPFNPDDC 3254

  Fly  3689 DVGSCLSHLLYQDGCCKRCKSEPLVEDKSSCLPVSLAESRTKEILKFPVQGHGTCVNADPIQGFT 3753
            :.|:.   .|..|.||..|::.       :|:       |.:.|.:..|.   .|.:...:: .|
Zfish  3255 EPGTI---KLDSDQCCYTCETR-------NCV-------RQRNITRLQVD---DCTSVQDLE-IT 3298

  Fly  3754 DCEGACSSGSKY----NTLTDMHEKFCTCCSIKSYHPISVKMICDDGHTFTQKHEVPSNCGCSP- 3813
            .|.|.|  ||.|    |.:|.     |:||.......:.||:.|.:|......:....:|.|:|
Zfish  3299 SCTGHC--GSMYSLYANQMTS-----CSCCQKDKSTSLPVKLKCTNGTEIDYNYTYIQSCKCTPM 3356

  Fly  3814 -CSE 3816
             |::
Zfish  3357 KCAD 3360

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hml	NP_524060.2	VWD	485..636	CDD:295339	43/163 (26%)
		C8	680..754	CDD:285899	15/77 (19%)
		TIL	758..811	CDD:280072	17/55 (31%)
		VWD	840..1015	CDD:214566	52/186 (28%)
		C8	1054..1121	CDD:214843	22/69 (32%)
		TIL	1131..1185	CDD:280072	17/56 (30%)
		TIL	1245..1298	CDD:280072	17/60 (28%)
		VWD	1327..1498	CDD:214566	52/172 (30%)
		C8	1535..1609	CDD:214843	33/73 (45%)
		Mucin2_WxxW	1751..1837	CDD:290069	10/88 (11%)
		TIL	1938..2005	CDD:280072	10/88 (11%)
		FA58C	2089..2223	CDD:238014	19/169 (11%)
		FA58C	2104..2225	CDD:214572	15/132 (11%)
		FA58C	<2299..2404	CDD:214572	18/105 (17%)
		FA58C	<2299..2403	CDD:238014	18/104 (17%)
		VWD	2703..2858	CDD:295339	25/155 (16%)
		C8	2893..2970	CDD:285899	10/76 (13%)
		TIL	2974..3030	CDD:280072	17/87 (20%)
		VWD	3035..3198	CDD:295339	39/180 (22%)
		C8	3257..3313	CDD:285899	19/59 (32%)
		VWC	3397..3451	CDD:302663	15/53 (28%)
		GHB_like	<3755..3813	CDD:304424	17/61 (28%)
LOC100536949	XP_021326445.1	VWD	65..211	CDD:214566	43/163 (26%)
		C8	247..314	CDD:312319	14/74 (19%)
		TIL	318..374	CDD:307783	17/55 (31%)
		VWD	414..565	CDD:306577	49/175 (28%)
		C8	606..680	CDD:214843	24/75 (32%)
		TIL	686..743	CDD:307783	17/56 (30%)
		VWD	870..1029	CDD:214566	52/173 (30%)
		C8	1067..1139	CDD:214843	33/71 (46%)
		Mucin2_WxxW	1483..1573	CDD:315900	20/102 (20%)
		Mucin2_WxxW	1931..2020	CDD:315900	19/121 (16%)
		VWD	2418..2583	CDD:214566	46/197 (23%)
		C8	2619..2679	CDD:312319	19/61 (31%)
		CT	3282..3355	CDD:214482	20/83 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D8946at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010