Protein Alignment Hml and LOC100498223

DIOPT Version :9

• Sequence 1: NP_524060.2
• Gene: Hml / 39529
• FlyBaseID: FBgn0029167
• Length: 3843
• Species: Drosophila melanogaster
• Sequence 2: XP_031756618.1
• Gene: LOC100498223 / 100498223
• -ID: -
• Length: 4761
• Species: Xenopus tropicalis
• Alignment Length: 5122
• Identity: 980/5122 - (19%)
• Similarity: 1535/5122 - (29%)
• Gaps: 2106/5122 - (41%)

  Fly   431 ERQKL--LALLAKYRDLERRSEWWSSEETVVTMSSYSLYQSNNLDIV----IDKTPRPALCTTWG 489
            :||||  .....|.::.....:.|        :.:..|..||..||:    ||.|  .::|::||
 Frog     3 KRQKLREAGCHCKAKEQTMGHQMW--------VLALMLSLSNAYDIIPGRPIDHT--NSICSSWG 57

  Fly   490 GINMKTFDGLVFKAPLSCSHTLITDKVSGTFDI---ILKACPYGSGYGCAHTLKILWQSVLYTFE 551
            ..:.|||||::::.|.:|::.|.||..:...|.   |.:|...||  ...|.:.:..:.|
 Frog    58 NFHYKTFDGVIYQFPGTCNYNLATDCGNSYHDFSIHIQRAIENGS--PVIHQINMQIKDV----- 115

  Fly   552 NLNGTMQLTTPIKKL-----PMPVQVMGMKVMPVAQHVQIDLESVGLKLDWDHRQYVSVQAGPQM 611
                |::|....:||     ..|....|:.:.....:..::.:: ||.|.|:....|.::...:.
 Frog   116 ----TIELKRDSEKLNGIGFETPYFSYGIFINKKDGYTMVNTKT-GLTLTWNQEDSVMLELDSKY 175

  Fly   612 WGKVGGLCGTLDGDPNTDLTSRTGKKLATVKAFADAWRVEDRSELC-QVENSAEMEFGMDSCEQS 675
            .||:.||||..:|.|.::........|..:: |.:...:.|.:..| .|:.|.:|  ...||.|
 Frog   176 NGKICGLCGDFNGMPVSNEFYMNDMPLNPIQ-FGNMQNINDPTVTCTNVDESQQM--NASSCGQ- 236

  Fly   676 KLQKAVSVCERLLANEKLGDCIKPFNYDALIRTCMADYCNCANREHPESCNCDAIAMLAKECAFK 740
                ..|||:..|:......|.........:..||.|.|:|::.:  .||.|:.:...:::|...
 Frog   237 ----YYSVCKSYLSQSAFSSCQDLLEVSDYVMACMLDVCSCSSAD--VSCLCNTLTEFSRQCTHA 295

  Fly   741 GIKLEHGWRNLEICPISCGFGRVYQACGPNVEPTCDSDLALPASKGACNE----GCFCPEGTV-- 799
            |...:: ||...:||..|....:|:..|    ..|.|..:....|..|.|    |||||:|||
 Frog   296 GGSPQN-WRTDTLCPKQCPGNMIYKESG----SPCISSCSHREVKSLCEEHDVDGCFCPDGTVWD 355

  Fly   800 QYKE-ACITRELCPCSLRGKEFKPESTVKKNCNTCTCKNGQWRCTEDKCGARCGAVGDPHYQTFD 863
            .|.. .||:...|.|..|.:.:.|.|.:..:|:.|.|..|:|.|....|...|...|..|:||||
 Frog   356 DYNNTGCISTTQCSCKFRDQLYAPGSNIINDCDECYCNEGKWVCAGGTCPKVCSIEGGAHFQTFD 420

  Fly   864 GKRYDFMGKCSYHLLK-----TQNTSVEAENVACSGAVSESMNFAAPDDPSCTKAVTIRFILRDG 923
            ||.|||.|:|.|.|.|     ..:.::.||...|:....|          :|.|  ||:|...:|
 Frog   421 GKLYDFFGRCYYLLSKIDLRSNDSYTIAAELTPCNAYSRE----------TCLK--TIKFYTDNG 473

  Fly   924 TPSVIKLDQGLTTIVNDKPIAKLPKMLGLGEVLIRRASSTFLTV--EFADGIRVWWDGVSRVYID 986
             .:::.:....:.::||..:: :|.:.|...|:  :.|.:|:.|  ||...|::.:..:.:|||.
 Frog   474 -KNILSIRADGSVLLNDLQVS-IPHITGSFSVI--QPSESFVVVETEFGLQIQIQFLPLMQVYIT 534

  Fly   987 APPSLRGQTQGLCGTFNSNTQDDFLTPEGDVETAVEPFADKWRTKDTCQFKAETHQGPHPCTLNP 1051
            ...|.....:||||.||....|||.|..|..|:....||:.|:.:.|||...|  ....||:.:.
 Frog   535 MDNSEENAVEGLCGNFNYIEGDDFTTSGGIDESTASAFANTWKMQSTCQDSVE--MLGDPCSFSV 597

  Fly  1052 EKKAQAEKFCDWI--LQDIFQDCHFLVEPEQFYEDCLYDTCACKDEMSKCFCPILSAYGTECMRQ 1114
            |.|..||.:|..:  ...||..||..|:|.::|:.|:.|||:| .....|.|..:|:|...|..:
 Frog   598 ETKTYAEFWCSKVKDSDSIFGTCHDTVDPNEYYKRCMSDTCSC-SRSDICMCAAMSSYARACAAK 661

  Fly  1115 G-VKTGWRMSVKECAV-KCPLGQVFDECGDGCALSCDDLPSKGSCKREC------VEGCRCPHGE 1171
            | :..|||....|..: .||..|.:......|..:|..| |.|  :::|      ::||.||.|.
 Frog   662 GKILWGWRNGTCENDIPSCPATQTYLYNITTCQPTCRSL-SLG--EKDCDSEFTPIDGCGCPDGT 723

  Fly  1172 YVNEDGECVPKKMCHCNFDGMSFRPGYKEVRPGEKFLDLCTCTDG-----------------VWD 1219
            ||||.|.|||...|.|.:.||..||.....:..|:    |:|..|                 .:|
 Frog   724 YVNEKGGCVPISECSCYYQGMYLRPYEVFYKRDER----CSCIAGKLNCASFINDTCSNGKVFFD 784

  Fly  1220 CQDAEPGDKDKYPPSSELRSKCAKQPYAEFTKC-----APKEPKTCKNMDKYVADSSDCLPGCVC 1279
            |...:.||                 |..:...|     .|..|              :|:.||||
 Frog   785 CSSLQKGD-----------------PIPQHRSCRTLNIGPVWP--------------ECISGCVC 818

  Fly  1280 MEGYVYDTSRLACVLPANCSCHHAGKSYDDGEKIKEDCNLCECRAGNWKCSKNGCESTCSVWGDS 1344
            .|| :.|.....|||.:.|.|.:..:.:..|..:.|:|..|.|.:|.|.|.:..|..||:::|..
 Frog   819 PEG-LLDDGTGGCVLESYCPCTYNNEVFPHGSSLNEECKSCACESGIWSCIQTPCYGTCTIFGSG 882

  Fly  1345 HFTTFDGHDFDFQGACDYVLAKGVFDNGDG-FSITIQNVLCGTMGVTCSKSLEIALTGHAEESLL 1408
            |:.|||...:||.|:|::|:|:....:.:| |.|..:|:.|||.|||||||::|.| |::|  |.
 Frog   883 HYITFDKKFYDFDGSCEFVVAQDYCGDVNGTFRIITENIPCGTTGVTCSKSIKIYL-GNSE--LK 944

  Fly  1409 LSADSAYST--DPNKTPIKKLRDSVNSKGHNAFHIYKAGVFVVVEVIPLKLQVKWDEGTRVYVKL 1471
            |:.:....|  ||.         ||..:    :...:.|:::|:.... .:...||:.|.:.::|
 Frog   945 LANEHLEQTVVDPL---------SVEEQ----YRAREVGLYIVIHTKD-DIFFIWDKKTSILIRL 995

  Fly  1472 GNEWRQKVSGLCGNYNGNSLDDMQTPSMGLETSPMLFGHAWKLQPHCSAPVAPIDACKKHPERET 1536
            .:.::..|.||||||:.|:.:|..|..:...::.|.||::||....|....:....|...|.|.:
 Frog   996 PSSYKGNVCGLCGNYDDNANNDFLTSQLIQASNVMDFGNSWKRSNLCPDANSIPQPCFSAPHRRS 1060

  Fly  1537 WAQLKCGALKSDLFKECHAEVPLERFWKRCIFDTCACDQGGDCECLCTAVAAYADACAQKGINIR 1601
            ||:.||..:.|::|..||:.|..:.|:..|:.|.|:||.||||||.|||:||||..|::..:.|.
 Frog  1061 WAEKKCDIINSNVFLSCHSRVNPKPFYDSCVNDVCSCDTGGDCECFCTALAAYAQQCSKVEVCID 1125

  Fly  1602 WRSQHFCPMQCD-----------------------PHCSDY---------KACTPAC-------- 1626
            ||:...||:.||                       .|.:.|         :.|.|.|
 Frog  1126 WRTPEICPIYCDYYNDDANECMWHYMSCGPQYSTFQHITKYCFSPPVTHLEGCYPVCPPERPYYD 1190

  Fly  1627 -----AVETCDN-FLDQGI--------AERMCNR--------------EN----CLEGCHIK--- 1656
                 .|:.||: |::..|        :..:|..              ||    |...|:|.
 Frog  1191 ERNKSCVDACDSCFINNRIYMINDTVPSNDICQTCKCDTNQQLRCTPIENPPAECFSKCYINGQT 1255

  Fly  1657 ----------------PCE-----------------------DGFIY-LND---TYRDCV----- 1673
                            .|:                       :|..| :||   |..||.
 Frog  1256 YNINDVVPSTDECSTCKCDINRQLSCSPIPNPPAKCISTCSINGQTYNINDVVPTSDDCSTCKCD 1320

  Fly  1674 ------------PKAECKPVCMVRDGKTFYEGDIT-FTDSCATCRCSKRKEI------------- 1712
                        |.|:|...|.: :|:|:...|:. .||.|:||:|...:::
 Frog  1321 TNRQLSCTPLQNPPAKCITTCSI-NGQTYNINDVVPTTDDCSTCKCDTNQQVTCAPVENPPAKCT 1384

  Fly  1713 ---------------------CSGVKCDVP---ATTGLPAPLVEGTT--------------LP-- 1737
                                 ||..|||..   :.|.|..|..:.||              :|
 Frog  1385 SKCYINGQTYNINDVVPTTDDCSACKCDSNRQLSCTPLQNPPAKCTTTCSINGQTYNINDVVPST 1449

  Fly  1738 ----TPLATQNQ---------------TKC-VKGWTR---------------WCDKDRDTS---- 1763
                |.|...||               :|| :.|.|.               :||.::..|
 Frog  1450 DDCYTCLCDTNQQVSCTLIQNPPAKCTSKCYINGLTYNLNDVIPTSDDCSTCYCDTNQQVSCTLI 1514

  Fly  1764 --------------DKSVRLNDEEKVPRYD----------------RMENVYGTCL-KQYMTKVE 1797
                          .::..:||  .||..|                .::|....|. |.|:....
 Frog  1515 QNPPAKCISKCYINGQTYNIND--VVPTTDDCSACLCDTNQQVSCTLIQNPPAKCTSKCYINGQT 1577

  Fly  1798 CRVKDTHEAPE-------QMDENVVCSLEEG--LRCIGKCH----DYELR---------AFCQCD 1840
            ..:.|.....:       ..::.|.|:|.:.  .:||.||:    .|.:.         :.|:||
 Frog  1578 YNINDVVPTTDDCSACLCDTNQQVSCTLIQNPPAKCISKCYINGQTYNINDVVPTTDDCSTCKCD 1642

  Fly  1841 EE-------LEPELPK------------------PTEKPQLGLACDA------------------ 1862
            ..       |:....|                  ||........||.
 Frog  1643 TNRQLSCTPLQNPPAKCITTCSINGQTYNINDVVPTTDDCYTCKCDTNQQVSCTLIQNPPAKCTS 1707

  Fly  1863 ---------AVVEYKEFPGDCH-------KFLHCQPKGVEGGWIYVEKTC---GEYMMFN---PT 1905
                     ::.:......||.       :.|.|.|  ::........||   |:....|   ||
 Frog  1708 KCYINGQTYSINDVVPTTDDCSTCKCDTTRQLSCTP--LQNPPAKCTTTCSINGQTYNINDVVPT 1770

  Fly  1906 MLICDHIATVTEIKPNCGLKPEPEPEFEPIKQC-------------------------------- 1938
            ...|......|..:..|  .|...|..:.|..|
 Frog  1771 TDDCYTCKCDTNQQVTC--TPIANPPAKCITTCSINGQTYNINDVVPTSDDCSTCKCDTNQQVSC 1833

  Fly  1939 -----PPGKIKSEC-------------------------ANQ-------------CENTCHYYGS 1960
                 ||.|..|:|                         .||             |.:.|:..|.
 Frog  1834 TLIQNPPAKCTSKCYINGQTYNINDVIPSTNDCSTCLCDTNQQMSCTLIQNPPANCISKCYINGQ 1898

  Fly  1961 ILKKRGLCQVGEHCKP---------GCVDELRP------DCPKLGKFWRDEDTCVHADEC----- 2005
            ......:....:.|..         .|.....|      .|...|:.:...|....||:|
 Frog  1899 TYSINDVVPTSDDCSTCKCDSTQQLSCTPIANPPAKCTSTCYINGQTYNINDVVPSADDCSTCKC 1963

  Fly  2006 --------------------PCMDKAEHY-VQPHKPVLGEFEVCQCIDN---AFTCVPNKP---- 2042
                                .|....:.| :....|...:...|.|..|   :.|.:.|.|
 Frog  1964 DTNRQLSCTPLQNPPAKCTTTCSINGQTYNINDVVPTTNDCYTCLCDTNQQVSCTLIQNPPAKCT 2028

  Fly  2043 -------------EPVPKDED------DDLDLVS------------------------VVP---- 2060
                         :.||..:|      |....||                        |||
 Frog  2029 SKCYINGQTYNIYDVVPTTDDCSACYCDTNQQVSCTLIQNAKCTSKCYINGQTYNINDVVPTTDD 2093

  Fly  2061 ---------------------------------------IYPVT-------------------LT 2067
                                                   :.|.|                   ..
 Frog  2094 CSTCKCDTTRQLSCTPLQNPPAKCTTTCSINGQTYNINDVVPTTDDCYTCKCDTTQQVTCSLIQN 2158

  Fly  2068 PPLQCSPE-----------RLIPKIENPAHSLPDSIFNASSQLAPEHGPKMARLTKEQPRGSWSP 2121
            ||.:|:.:           .::|..::.:..|.|:....|..|.|.   ..|:.|.:......:.
 Frog  2159 PPAKCTSKCYINGQTYNINDVVPTTDDCSACLCDTNQQVSCTLIPN---PPAKCTSKCYINGLTY 2220

  Fly  2122 SINDQMQYLELNFAKPEPFYGVVMAGSPEFDNYVTLFKILHSHDGIAYHYLVDETEKPQMFNGPL 2186
            :|||.:                     |..|:.:|.              |.|..   |..:..|
 Frog  2221 NINDVV---------------------PTSDDCLTC--------------LCDTN---QQVSCSL 2247

  Fly  2187 DSRAPVQTLFKIPIEASSLRI---YPLKWHGSIAM--RVELLICGDKEEPKPVPTVST------- 2239
            ....|.:...|..|...:..|   .|.....|...  ..:.|.|.....| |....||
 Frog  2248 IQNPPAKCTSKCYINGQTYNINDVVPTSDDCSSCKCDSTQQLSCTPIANP-PAKCTSTCYINGQT 2311

  Fly  2240 -------------------------ILPITERPARLVDLECIDLMGVDEGKMYQ----------- 2268
                                     ..|:...||:     |.....:: |:.|.
 Frog  2312 YNINDVVPSADDCSTCKCDTNRQLSCTPLQNPPAK-----CTTTCSIN-GQTYNINDVVPTTDDC 2370

  Fly  2269 -------DQVQSSSLWQQPNL---------GKKLQLLELL---------------KLSTPLAWRP 2302
                   :|..|.:|.|.|..         |:...:.:::               ::|..|...|
 Frog  2371 YTCLCDTNQQVSCTLIQNPPAKCTSKCYINGQTYNINDVVPTSDDCSACLCDTNQQVSCTLIQNP 2435

  Fly  2303 LANSQNEFIEFDFLEPRNISGFV-------------------------------TKGGPDGWVTG 2336
            .|...::.:         |:|.:                               .|.....:|.|
 Frog  2436 PAKCTSKCV---------INGQIYNINDVVPTTDECSACYCDTNQQVSCTVIQNAKCTSKCYVNG 2491

  Fly  2337 YKVMFSKKKPTWN---------------TVLST---------DGQA----RIFEANHDAETERRH 2373
            .....:...||.:               |::..         :||.    .:...:.|..|.:..
 Frog  2492 QTYNINDVVPTTDDCSACYCDTNQQVSCTLIQNAKCTSKCYINGQTYNINDVVPTSDDCSTCKCD 2556

  Fly  2374 H--------FKNP----ILTQYIK--------IVPA-------YWEKNINMRIEPL--------- 2402
            .        .:||    ..|.||.        :||:       ..:.|..:...||
 Frog  2557 STQQLSCSPIENPPAKCTSTCYINGQTYNINDVVPSADDCSTCKCDTNRQLSCTPLQNPPAKCTT 2621

  Fly  2403 -------------------GCFLPYPEIQRQVPVE--ESKPTKC-----------NICDGVSTSS 2435
                               .|:....:..:||...  ::.|.||           ||.|.|.|:.
 Frog  2622 TCSINGQTYNINDVVPTTDDCYTCKCDTNQQVSCSLIQNPPAKCTSKCYINGQTYNINDVVPTTD 2686

  Fly  2436 STTGCQCQDQLFWDGNTCVQHNLCP---------CIENYVSYPIG-------------------- 2471
            ..:.|.|      |.|..|...|.|         |..|..:|.|.
 Frog  2687 DCSTCMC------DSNQQVSCTLIPNPPAKCTSKCYINGQTYNINDVVPTTDECSACLCDTNQQV 2745

  Fly  2472 --SKFENSAC--------------------EDC-------------------------VCVLGGH 2489
              :..:|:.|                    :||                         .|.:.|.
 Frog  2746 SCTLIQNAKCTSKCYINGQTYNINDVVPTTDDCSTCKCDSTQQLSCTPIANPPAKCTSTCYINGQ 2810

  Fly  2490 K------------------------NCKPKKCPPC-------LGGK---LRPVI--TSDCF-CKC 2517
            .                        :|.|.:.||.       :.|:   :..|:  |.||: |.|
 Frog  2811 TYNINDVVPSADDCLTCKCDTTRQLSCTPLQNPPAKCTTTCSINGQTYNINDVVPTTDDCYTCLC 2875

  Fly  2518 E------------PCPKHQRLC-------------PSSGDC------IPEILWCNGVQD----CA 2547
            :            |..|....|             |::.||      ..:.|.|..:::    |.
 Frog  2876 DTNQQVSCSLIQNPPAKCTSKCYINGQTYNINDVVPTTDDCSTCTCDSTQQLTCTPIENPPAKCT 2940

  Fly  2548 ------------DDEDASCSDSFTVEPDVSREK-------------------------------- 2568
                        :|...|..|..|.:.|.:|:.
 Frog  2941 STCYINGQTYNINDVVPSADDCSTCKCDTNRQLSCTPLQNPPAKCTTTCSINGQTYNINDVVPTT 3005

  Fly  2569 --------NETEVITCPVPVCPPQMKIRITEK-----KSRKMSK-----------MFTFSKQVS- 2608
                    :.|:.:||.:.|.||   .:.|.|     ::..::.           |...::|||
 Frog  3006 DDCYTCKCDTTQQVTCTLVVNPP---AKCTSKCYINGQTYNINDVVPTTDDCSACMCDTNRQVSC 3067

  Fly  2609 -------------IVDDGTTITKTKFISSKEQILA-------------MPN-----------REL 2636
                         .|.:|.|......:.:.:..||             :||           ...
 Frog  3068 TLIPNPPAKCISKCVINGQTYNINDVVPTTDDCLACHCDTNQQVSCSLIPNPPAKCISKCYINGQ 3132

  Fly  2637 DFQLEE-----------QCD---EFTCVPI---PSKQV--------------------------- 2657
            .:.:.:           .||   :.:|.||   |:|..
 Frog  3133 TYNINDVVPTTDDCSTCMCDSTQQLSCTPIENPPAKCTTTCYINGQTYNINDVVPSADGCSSCIC 3197

  Fly  2658 DKNETVTCT-----EPKCP-------EKYDVELDMSASKVGDCLRYSCVLRPNK----------- 2699
            |.|..::||     ..||.       :.|::. |: .....||  |:|:...||
 Frog  3198 DTNRQLSCTPLQNPPAKCTTTCSINGQTYNIN-DV-VPTTDDC--YTCLCDTNKQVSCSLIENPP 3258

  Fly  2700 -----------------------DDV--------------------------CEISGKSF----- 2710
                                   ||.                          |.|:|:::
 Frog  3259 AKCIHKCYINGLTYNINDVVPTSDDCSTCLCDTNQQLSCSLIENPPAKCISKCYINGQTYNINDM 3323

  Fly  2711 --TTFDGTVFKYG-------------PCSHILARDIHSSSWSIS----VHQQCS----DETRKV- 2751
              ||.|.:..|..             |...|....|:..:::|:    ....||    |..|::
 Frog  3324 VPTTDDCSTCKCDTNRQLSCTPLQNPPEKCITTCSINGQTYNINDVVPTTDDCSVCKCDTNRQLS 3388

  Fly  2752 ----------CHKVITIQ---------------------DTEAGNELILLPH------LKLKFNG 2779
                      |....:|.                     ||.......|:|.      .|...||
 Frog  3389 CTPLQNPPAKCVTTCSINGQTYNINDVVPTTDDCYTCKCDTNQQVSCTLIPSPPAKCISKCYING 3453

  Fly  2780 YEFTVQQLI----NSPICK--------ASFVVSQPGKTLL-------------AVSTKYGFWVQL 2819
            ..:.:..::    :...||        .:.:.:.|.|.:.             .|.|.
 Frog  3454 QTYNINDVVPTTDDCSACKCDTNQQVSCTLIQNPPAKCISKCYINGQTYNINDVVPTS------- 3511

  Fly  2820 DDIGIVKVG----ISSKFIRTVDGLCGY--------YNGNQ----KDD----------------- 2851
            ||....|..    :|...|......|.|        ||.|.    .||
 Frog  3512 DDCSACKCDTNQQVSCTLIPNPPAKCIYKCYINGQTYNINDVVPTSDDCSTCLCDTNQQLSCTPL 3576

  Fly  2852 KRSP---------DGQ------IIPNTEKFGDSWYDKR--------------------------- 2874
            :..|         :||      ::|.|:.......|..
 Frog  3577 QNPPAKCISKCYINGQTYNINDVVPTTDDCSTCICDTTRQLSCTPLQNPPAKCTTTCSINGQTYN 3641

  Fly  2875 ----IP-KDQCGDLKC--PREMQAKALQ------------------------------------- 2895
                :| .|.|...||  .|::....||
 Frog  3642 INDVVPTTDDCSTCKCDTTRQLSCTPLQNPPAKCTSTCSINGQTYNINDVVPTTDVCSTCKCDSN 3706

  Fly  2896 ---LCNIIHHPTFARC-HKAVNYKQFLNNY--------CLEAAC------NCMMANNGDPAAC-- 2940
               .|.:|.:|. |:| .|.....|..|.|        |....|      :|.:..| .||.|
 Frog  3707 RQVSCTLIQNPP-AKCTSKCYINGQTYNFYDVVPTTDDCYTCLCDTNQQVSCTLIQN-PPAKCTS 3769

  Fly  2941 --------------------------------KCNILESFVKKCLS------------------- 2954
                                            .|:.:.:..:||:|
 Frog  3770 KCYINGQTYNINDVVPTTDDCSTCLCGADRQLSCSPIPNPPQKCISCIINNRSYQPGERVPSSDP 3834

  Fly  2955 ------------------------------------------------VNPLVQLTTWRAVAQCE 2971
                                                            :.|...::|:.:...|.
 Frog  3835 CLICQCAANLQQSCSSDPACCKMDDIATTTPPTYITATTVGSNNGATLIPPSTIISTYNSSVLCA 3899

  Fly  2972 ----IN---------CPSPL--------------------------------VHTDCYKRRCEPS 2991
                :|         |.:|:                                :...|||..|:.|
 Frog  3900 QRICVNGKITQTTTLCSTPVTTPTTTATTTTTCSCTYNGIVYAPGQEITRSNILGKCYKVMCDGS 3964

  Fly  2992 C--------------------------------------------------------DNVHGDDC 3000
            |                                                        ..:.....
 Frog  3965 CGQTPAVEIPCDTTTTITTTPTTTKTTTKTTTTTPTTTKTTTTATTTKTTTKTTKSSTTIISTTT 4029

  Fly  3001 PVLPDACFPGCYCPEG---------TVRKGPNCVPISECK----------------------DCV 3034
            |.:|...:..|.|.:.         .|.||  |:|..:.|                      .|:
 Frog  4030 PCVPYTNWQICNCTKAICNAAGQLQIVEKG--CIPPPQIKCANQMQPIAVPDDDLCCWHWECPCM 4092

  Fly  3035 CNSLGASKYMTYDRKSFSFNGNCTYLLSRDVVLPGVHTFQVYVSMDDCKKLGQPTPVEGGSCAKS 3099
            |...|...|:|:|...:::||||||:|..::| ..:..|.:|:...||   |..|   |.:|.::
 Frog  4093 CAGWGDPHYLTFDGTYYTYNGNCTYVLVEEIV-KTIDNFGIYLDNYDC---GDTT---GVTCPRN 4150

  Fly  3100 LHILNGDHVIHVQRVPQKPKSLQVLVDGFEVKKIPYKDSWISLRQVVGKELVLSLPESHVELTAS 3164
            |.:......|.:......|.:|:..::| ::..:||....:.|.: .|...|:.:|:....:|
 Frog  4151 LTVQYETQEITISPTSFAPINLETRING-QLVLLPYTKYGLKLYK-SGVYYVVEIPDLKTNVT-- 4211

  Fly  3165 FEDLIFSLGVPSIKYGSKMEGLCGDC-NGNAGNDLQPNPAKKKAGVDVIQSWQADEPKLGLVEEC 3228
            :..:.|::.:|..|:.:...|.||.| |..|.:.:..|....|..:.:..|:...:|   ...:|
 Frog  4212 YNGITFTIKMPYGKFYNNTHGQCGTCTNSQADDCMMANGTIAKDCITMADSYIVSDP---AKPQC 4273

  Fly  3229 LSE-DVPKEHCIPLPPE-KDPCLQFYNAELFGKCPLAVDPIAYVSACQQDICKPGNTQQGVCVAL 3291
            .|. .:||    |:.|. |..........:|..|..|..|..:..||..|.|...|:.. .|.:|
 Frog  4274 KSNTPLPK----PINPTCKSSLCDLIMGPIFKACHAAQPPQPFYQACLYDSCNVANSNI-ECTSL 4333

  Fly  3292 AAYAKECNQHGICTNWRRPQL-CPYECPSDMVYEPCG--CAKNCDTIKALSEFDAVSLKNEAVVH 3353
            ..||..|..||||..||...| ||..||||.||..||  ....|.|..:    ||.:|||:..|
 Frog  4334 QHYATICGDHGICIPWRSQALDCPITCPSDRVYNACGSPIPLTCQTTPS----DAAALKNDKRV- 4393

  Fly  3354 TVKTDEMCLSSERFEGCFCPP-----GKVMDGGQCVPEIACTKCDDGLHLPDEKWKKDKCTECQC 3413
                         .||||||.     ...:|  .||.:..|...|:......|.:..: |..|.|
 Frog  4394 -------------VEGCFCPTDTKPFSAAID--ICVSDCGCVGPDNVPRSYGESFVFN-CEICTC 4442

  Fly  3414 DSKGK-TTCVEKKC--QVEENICAEGYRPETIVS-VDECCPR--YRCVPETKDPSKLCLAPLVPI 3472
            ...|: .||..::|  .|.|....||:...|..| .::||..  .||     ||| || :.::|.
 Frog  4443 LEGGRGITCQNQECLDVVNEQCILEGFYSVTQPSATNKCCNETVCRC-----DPS-LC-SDILPK 4500

  Fly  3473 CGPGQFKKEKKDVNGCSQYICECIPKDQCEIIELRELLPGEIIVNVEEGCCPTQKIECKPETCPK 3537
            ||||
 Frog  4501 CGPG------------------------------------------------------------- 4504

  Fly  3538 APVNCQERFYEVKTIKEPGMCCSKHSCVPPKDLCI---VQYELDEATKFTKTVGDKWTHAKEVCK 3599
                     |.:|...|.|.||..:|| .||.:|:   .:| |..:..:|           |.|
 Frog  4505 ---------YAMKGGIEDGHCCPTYSC-EPKQVCVSGNAEY-LPGSHVYT-----------ENC- 4546

  Fly  3600 QETCSYGPDGNAQVVSTLE-QCLTDCAPGFSYQNLDKTKCCGKCVQTSCIFE-----QKLYEVNA 3658
             |.|....:||...::... .|...|..||..:....:.|||.|.||:|:..     :.:...:.
 Frog  4547 -ENCICAQNGNNFTIACDPIVCNIQCPAGFEVKPNSPSDCCGSCQQTNCVVNYDGSYRLMNPGDV 4610

  Fly  3659 LWKSADNCTTYSCLKKDGQFLVTTSREVCP-------DVGSCLSHLLYQDGCCKRCKSEPLVEDK 3716
            |....|.||.|.|...:|||:.|.|:..||       :.||.   .|...||||.|
 Frog  4611 LPSVTDTCTMYKCSLINGQFVTTVSQISCPILNEDDCEPGSI---QLSPSGCCKTC--------- 4663

  Fly  3717 SSCLPVSLAESRTKEILKFPVQGHGTCVNADPIQGFTD-----------------CEGACSSGSK 3764
                                :|.:|||    .:|.|.|                 |||:|.:.|.
 Frog  4664 --------------------IQKNGTC----SVQAFDDYLTYQGCTSATRLRMSRCEGSCGTFSM 4704

  Fly  3765 YNTLTDMHEKFCTCCSIKSYHPISVKMICDDGHTFTQKHEVPSNCGC--SPC 3814
            ::.........|:||........:||:.|.||.:....:.....|.|  |.|
 Frog  4705 FSADAQAMSHKCSCCQEVQTTTNNVKLQCPDGTSLDYNYIDVQECQCTGSQC 4756

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hml	NP_524060.2	VWD	485..636	CDD:295339	39/158 (25%)
		C8	680..754	CDD:285899	17/73 (23%)
		TIL	758..811	CDD:280072	19/59 (32%)
		VWD	840..1015	CDD:214566	55/181 (30%)
		C8	1054..1121	CDD:214843	23/69 (33%)
		TIL	1131..1185	CDD:280072	22/59 (37%)
		TIL	1245..1298	CDD:280072	15/57 (26%)
		VWD	1327..1498	CDD:214566	57/173 (33%)
		C8	1535..1609	CDD:214843	32/73 (44%)
		Mucin2_WxxW	1751..1837	CDD:290069	23/157 (15%)
		TIL	1938..2005	CDD:280072	19/156 (12%)
		FA58C	2089..2223	CDD:238014	22/138 (16%)
		FA58C	2104..2225	CDD:214572	19/125 (15%)
		FA58C	<2299..2404	CDD:214572	24/218 (11%)
		FA58C	<2299..2403	CDD:238014	24/217 (11%)
		VWD	2703..2858	CDD:295339	43/287 (15%)
		C8	2893..2970	CDD:285899	24/232 (10%)
		TIL	2974..3030	CDD:280072	17/152 (11%)
		VWD	3035..3198	CDD:295339	42/163 (26%)
		C8	3257..3313	CDD:285899	21/56 (38%)
		VWC	3397..3451	CDD:302663	16/57 (28%)
		GHB_like	<3755..3813	CDD:304424	15/59 (25%)
LOC100498223	XP_031756618.1	VWD	53..199	CDD:395046	39/157 (25%)
		C8	246..308	CDD:400886	13/64 (20%)
		TIL	312..368	CDD:410995	19/59 (32%)
		VWD	397..563	CDD:214566	55/181 (30%)
		C8	600..670	CDD:214843	24/70 (34%)
		TIL	680..737	CDD:410995	22/59 (37%)
		VWD	865..1022	CDD:214566	57/173 (33%)
		C8	1061..1133	CDD:214843	32/71 (45%)
		VWD	4083..4250	CDD:214566	43/177 (24%)
		C8	4291..4354	CDD:400886	20/63 (32%)
		CT	4672..4753	CDD:214482	18/80 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	76	1.000	Domainoid score	I8782
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000