Protein Alignment Hml and muc2

DIOPT Version :10

• Sequence 1: NP_524060.2
• Gene: Hml / 39529
• FlyBaseID: FBgn0029167
• Length: 3843
• Species: Drosophila melanogaster
• Sequence 2: XP_031757181.1
• Gene: muc2 / 100493286
• XenbaseID: XB-GENE-6046886
• Length: 4693
• Species: Xenopus tropicalis
• Alignment Length: 4982
• Identity: 911/4982 - (18%)
• Similarity: 1412/4982 - (28%)
• Gaps: 1972/4982 - (39%)

  Fly   484 LCTTWGGINMKTFDGLVFKAPLSCSHTLIT--DKVSGTFDIILKACPYGSGYGCAHTLKILWQSV 546
            :|:|||.::.|||||..::.|..||:.|.:  .:....|.:.:|. ...:|:.....:.:..:.|
 Frog    35 VCSTWGNLHYKTFDGDFYQYPGLCSYELASHCGEAYREFSVHVKH-TNATGHPLVEKIVVTIKDV 98

  Fly   547 LYTFEN----LNGTMQLTTPIKKLPMPVQVMGMKVMPVAQHVQIDLESVGLKLDWDHRQYVSVQA 607
            :....:    :||.:..|        |....|:.:.....::::..:| ||.|.|:....:.|:.
 Frog    99 IVEIRSSLVVVNGQIAKT--------PYYSYGILLHKNDAYIKLYTKS-GLTLMWNKEDAIMVEL 154

  Fly   608 GPQMWGKVGGLCGTLDGDPNTDLTSRTGKKLATVKAFADAWRVEDRSELCQVENSAEMEFGMDS- 671
            .|:...:..||||..:|.|..:........|..|: |.:...:.|.:|.|  .|..|.:....|
 Frog   155 DPKYNNQTCGLCGDYNGIPFYNEFIGESFHLTPVQ-FGNLQNIYDPAEHC--TNPDETQIAETSF 216

  Fly   672 CEQSKLQKAVSVCERLLANEKLGDCIKPFNYDALIRTCMADYCNCANREHPESCNCDAIAMLAKE 736
            |.|.:     ||||..||:....||....|.:|.|:.||.|.|:| .:.....|.|..|:..:::
 Frog   217 CSQYR-----SVCEEHLAHPAFTDCQSLLNTEAYIKACMLDMCSC-GQSQDAFCLCSTISEFSRQ 275

  Fly   737 CAFKGIKLEHGWRNLEICPISCGFGRVYQACGPNVEPTCDSDLALPASKGACNE----GCFCPEG 797
            |:..|.: ...||....||.:|....:||..|    ..|.|..:.......|.|    |||||||
 Frog   276 CSHAGGR-PGTWRTENFCPKTCPGNMIYQESG----SPCTSSCSRLEIHSLCEEHFMDGCFCPEG 335

  Fly   798 TV---QYKEACITRELCPCSLRGKEFKPESTVKKNCNTCTCKNGQWRCTEDKCGARCGAVGDPHY 859
            ||   ...:.||....|.|..:|..:.|.:|::.:||.|.|..|:|:||::.|...|...|..|:
 Frog   336 TVLDDHNNKGCIPLNQCQCKHQGTLYNPGATIQNDCNECNCITGRWQCTKNSCPRVCSIEGGAHF 400

  Fly   860 QTFDGKRYDFMGKCSYHLLKTQNTSVEA---ENVACSGAVSESMNFAAPDDPSCTKAVTIRFILR 921
            .|||||:|.|.|.|.|.|||.:.....|   |...||.:..|          :|.|.|.   :|.
 Frog   401 NTFDGKKYTFHGNCYYVLLKGRRNESHALLGELAPCSSSARE----------TCLKTVK---MLT 452

  Fly   922 DGTPSVIKLDQGLTTIVNDKPIAKLPKMLGLGEVLIRRASSTFLTVEFADGIRVWWD-----GVS 981
            |...:|:..:...|.::|:..|: ||.:.....:|  :.:.:::.|:...|:.:...     .:.
 Frog   453 DNLQNVVTFNADGTVLMNELEIS-LPHVTASFSIL--QPTESYIIVQSIFGVELQIQLLPKTPMM 514

  Fly   982 RVYIDAPPSLRGQTQGLCGTFNSNTQDDFLTPEGDVETAVEPFADKWRTKDTCQFKAETHQGPHP 1046
            :::|:....:....|||||.||....|||.|..|..|.....||:.|:...||..:.:...  .|
 Frog   515 QLFINMESPITSGLQGLCGNFNYMEADDFTTSAGLAEATASAFANTWKAHPTCPEQKDWLD--DP 577

  Fly  1047 CTLNPEKKAQAEKFCDWILQ--DIFQDCHFLVEPEQFYEDCLYDTCACKDEMSKCFCPILSAYGT 1109
            |:||.|.:.....:|..:.|  ..|..||..::|..:.:.|.||.|.|||. ..|.|.|:|:|..
 Frog   578 CSLNVESQNYGNHWCTHLQQPESPFAKCHSTIDPTDYIKTCQYDVCNCKDS-EACMCAIMSSYVR 641

  Fly  1110 ECMRQG-VKTGWRMSVKECAVK-CPLGQVFDECGDGCALSCDDLPSKGSCKREC------VEGCR 1166
            .|..:| :..|||..:.|..|: ||..|::......|..:|..| ::|  ::.|      |:||.
 Frog   642 ACAAKGIILWGWRSGICEGDVRSCPSSQMYLYNLTTCQPTCRAL-AEG--EKACMSDFTPVDGCG 703

  Fly  1167 CPHGEYVNEDGECVPKKMCHCNFDGMSFRPGYKEVRPGEKFLDLCTCTDGVWDCQDAEPGDKDKY 1231
            ||.|||:||:.:|||...|.|...|....|........|:    |||.:|...| .....|..|
 Frog   704 CPDGEYLNENDKCVPISKCSCYNKGTYLNPQDVIYIQNER----CTCHNGRLIC-TTHTDDSCK- 762

  Fly  1232 PPSSELRSKCAKQPYAEFTKCAPKEP--KTCK--NMDKYVADSSDCLPGCVCMEGYVYDTSRLAC 1292
              |.::...|.|.| |:    |...|  ::||  .:|.:   .::|..||||.|| :.|.....|
 Frog   763 --SGKIYFDCNKIP-AD----ASVTPVHRSCKTLTLDMF---QTECRSGCVCPEG-LLDDGMDGC 816

  Fly  1293 VLPANCSCHHAGKSYDDGEKIKEDCNLCECRAGNWKCSKNGCESTCSVWGDSHFTTFDGHDFDFQ 1357
            |....|.|.|..:.:..|::|:.|||.|.|::|.|.|:...|..||:::|..|:.|||...:||.
 Frog   817 VPEDRCPCVHNQEHHHHGKEIQVDCNTCSCKSGRWNCTNTVCYGTCTIYGSGHYVTFDNKIYDFD 881

  Fly  1358 GACDYVLAK---GVFDNGDGFSITIQNVLCGTMGVTCSKSLEIALTGHAEESLLLSADSAYSTDP 1419
            |.|::|.|:   |...:...||:..:|:.|||.|||||||:::.| |..|..|   |:
 Frog   882 GNCEFVAAQDYCGQHQSQGNFSVITENIPCGTTGVTCSKSIKVFL-GSTELKL---AE------- 935

  Fly  1420 NKTPIKKLRDSVNSKGHNAFHIYK-AGVFVVVEVIPLKLQVKWDEGTRVYVKLGNEWRQKVSGLC 1483
                 |::.:::.......:::.: .|:::|:|. ...:.:.||:.|.:.:|:...::.|:.|||
 Frog   936 -----KQIEETLGDSAKRVYYLSREVGLYLVIEA-NNGIMLIWDKKTTIIIKVSPAYKGKLCGLC 994

  Fly  1484 GNYNGNSLDDMQTPSMGLETSPMLFGHAWKLQPHCSAPVAPIDACKKHPERETWAQLKCGALKSD 1548
            ||::|||.:|..|..|....:.:.||::||:.|.|......|..|...|.|:.||:.:||.:|||
 Frog   995 GNFDGNSNNDFTTNHMMQVNNVLEFGNSWKVDPKCPDVTQEIHPCTSTPHRKAWAEKQCGLIKSD 1059

  Fly  1549 LFKECHAEVPLERFWKRCIFDTCACDQGGDCECLCTAVAAYADACAQKGINIRWRSQHFCPMQCD 1613
            .||.||::|....|::.|:.|.|:||.||||||.|||||.||..|.:.|..:.||:...||:.||
 Frog  1060 TFKTCHSKVNPSSFYEACVNDACSCDTGGDCECFCTAVAVYAQECNKAGACVNWRTPDICPIFCD 1124

  Fly  1614 --------------------PHCSD------------YKACTPACAVE--TCDNFLDQGIAERMC 1644
                                |.|..            .:.|.|:|..:  ..|......:.|..|
 Frog  1125 YYNPKDECQWHYYPCGFHDIPTCRSINNIYSNVTVNYLEGCYPSCPTDKPIFDELTQLCVTEDQC 1189

  Fly  1645 ------------------------------------NRENCL---------EG-----------C 1653
                                                |:..|:         ||           |
 Frog  1190 GCYINGTHYPPGVPVPPKEPCYTCMCGHDSKVNCNYNQSACVCVINGTIYEEGQIISNQEQSGIC 1254

  Fly  1654 HIKPCEDGFIYLNDTYRDCV---------------PKAECKPV----------CM---VRDGKTF 1690
            ..:.|.:|.|..|.|.  |:               ||.....|          |:   :.:...:
 Frog  1255 IEEKCINGTIQANVTI--CLSTTVATIPTTSLTTPPKTSTSTVTTTPPIPSTTCVSGWICEWSQW 1317

  Fly  1691 YE----------GDITFTD----------------SCAT------------------------CR 1705
            |:          ||:...|                .|..                        ||
 Frog  1318 YDVNKPQEGPDGGDLETYDEIRRHGFTICQKPEDIQCRAASAPDVSLDQIGQTVHCDASYGLICR 1382

  Fly  1706 CSKRKEICS----------GVKC---------------------------------------DVP 1721
            .|::||..|          .|.|                                       .||
 Frog  1383 NSEQKEDASLWQRCFNYEIRVSCCVWDCLSTATTTVPTTTTTAPTTTTTVPTTTTTAPTTTTTVP 1447

  Fly  1722 ATTGLP----------------APLVEGTTLPTPLAT---------------------------- 1742
            .||..|                ....|.||.|||..|
 Frog  1448 TTTTTPPTTTTTPTTTASSTVVTTTTEETTTPTPTTTLETTTSTSTSPTTTESTTTETTSTTMST 1512

  Fly  1743 -----------------------------------------QNQTKC------------------ 1748
                                                     ::.|:|
 Frog  1513 TTTTTSTPGSSTSTPLSTSTSVSTTSSPTTKITSITTSPTSESTTECTTEVPEETTPITTTTTTS 1577

  Fly  1749 -------------------VKGWTRWCDKDRDTSDKSVRLNDEEKVPRYDRMENV--YGTCLKQY 1792
                               :..||.|.    |.|..:...|..:    ::..||:  .|..:.:.
 Frog  1578 MITSSETSRTTLPTTTCAPICWWTEWF----DVSYPAYETNGGD----FETYENIRKAGKEICEK 1634

  Fly  1793 MTKVECRVKDTHEAP-EQMDENVVCSLEEGLRCIGK--------CHDYELRAFC---QCDEELEP 1845
            ...:.||.:...:.| :|:.:.|.|.:..||.|..|        |::|::..:|   .|.....|
 Frog  1635 PENISCRAERFPDTPLDQLGQKVTCEVSNGLICYNKDQTGFLPVCYNYQISVYCCEPGCTSPTTP 1699

  Fly  1846 --------------------------ELPKPTEKPQLGL-------------------------- 1858
                                      :.|..|..|...:
 Frog  1700 TSTTTPTSTTTPTSTTTTTSTSTSTTQPPSTTTPPTTTIPTSTTLETTTTTVSTTTSITTTPTPC 1764

  Fly  1859 --AC------DAAVVEYKEFPGDCHKFLHCQPKGVEGGWIYVEKTCGEYMMFNPTMLICDHIATV 1915
              .|      |.:...|:...||...:.:.:..|.|                     ||:
 Frog  1765 APICWWTEWFDVSYPAYETNGGDFETYENIRKAGKE---------------------ICE----- 1803

  Fly  1916 TEIKP---NCGLKPEPEPEFEPIKQCPPGKIKSECAN--QCEN--------TCHYYGSILKKRGL 1967
               ||   :|..:..|:...:.:.|    |:..|.:|  .|.|        .|:.|
 Frog  1804 ---KPENISCRAERFPDTPLDQLGQ----KVTCEVSNGLTCYNKDQTGFLPVCYNY--------- 1852

  Fly  1968 CQVGEH-CKPGCVDELRP----------------------------------------------- 1984
             |:..: |:|||.....|
 Frog  1853 -QISVYCCEPGCTSPTTPTSTTTPTSTTTPTSTTTPTSTTTTTSTSTSTTQPPSTTTLTTTTIPT 1916

  Fly  1985 ----------------------DCPKLGKF--WRDE-----------------------DTCVHA 2002
                                  .|..:..:  |.||                       :.|...
 Frog  1917 STTLETTTTTVSTTTSITTTPTPCAPICWWTEWFDESYPAYETNGGDFETYENIRNAGKEICEKP 1981

  Fly  2003 DECPCMDKAEHYVQPHKPV--LGEFEVCQCIDNAFTCVPNKPEPVPKDEDDDLDL-----VSVV- 2059
            :...|  :||.:  |..|:  ||:...|. :.|..||       ..||:...|.:     :||.
 Frog  1982 ENISC--RAEKF--PDTPLDQLGQKVTCD-VSNGLTC-------YNKDQTGFLPVCYNYQISVYC 2034

  Fly  2060 -------PIYPV-TLTPPLQCSPERLIPKIENPAHSLPDSIFNASSQLAPE-----------HGP 2105
                   |..|. |.||....:|.........   :.|.|....:|...|.           |.|
 Frog  2035 CEPGCTSPTTPTSTTTPTSTTTPTSTTTPTST---TTPTSTTTPTSTTTPTSTTTTTSTSTIHPP 2096

  Fly  2106 KMARLTKEQPRG-------------------------------------------------SWSP 2121
            .....|  ||..                                                 |:.|
 Frog  2097 STTSTT--QPPSTTTTPTTTIPTSTTLETTTLSTTTTTSITTTPTPSCVCWWTEWFDVSYPSYEP 2159

  Fly  2122 SINDQMQYLELNFA------KPE------------PFYGVVMAGSPEFDNYVTLFKILHSHDG-- 2166
            |..|...|..:..|      |||            |...:....:.|..|.:|.:.  ....|
 Frog  2160 SGGDFETYENIRNAGHEICEKPENISCRAERFPDTPLDQLGQKVTCEVSNGLTCYN--KDQTGFL 2222

  Fly  2167 -IAYHYLVD----------------------------------ETEKPQMFNGPLDSRAPVQTLF 2196
             :.|:|.:.                                  .|..|.....|..:..|..|..
 Frog  2223 PVCYNYQISVYCCNPPDCTSTTTPTSTTTPTSTTTPTSTTTPTSTTTPTSTTTPTSTTTPTSTTT 2287

  Fly  2197 KIPIEASSLRIYPLK--------------------WHGSIAMRVEL-----LICGDKEEPKPVPT 2236
            .......:....|..                    .|.|.......     ..........|..|
 Frog  2288 HTSTTTPTSTTTPTSTTTHTSTTTPTSTTTPTSTTTHTSTTTPTSTTTPTSTTTTSTSTSHPPST 2352

  Fly  2237 VSTILP---------ITERPARLVDLECIDLMGVDEGKMYQDQVQSS------------------ 2274
            .||.||         .|...:..::...........|.:|.:....|
 Frog  2353 TSTSLPPSTTTTTTTTTVPTSTTLETTTTPFSTTTSGTIYTESTPVSTTTAPTTTLETSTTHTIP 2417

  Fly  2275 -SLWQQPNLG--------------------KK--------------------------LQLLELL 2292
             |..|:....                    ||                          |...|..
 Frog  2418 TSTTQETTTSVPTTTSGTETFTSTTTSTTTKKTTTTSETTSTTPGPTTTSVSSTTTETLTTTECT 2482

  Fly  2293 -----------------KLSTPLAWRPLANSQNEFIEFDFLEPRNISG----FVTKGGPDGWVTG 2336
                             :|:|.....|.:.:|..........|...||    ..|...|....|.
 Frog  2483 TEETEETSPTTTHTTTPRLTTTPHTIPTSTTQGTTTTTTTTVPTTTSGTETYTSTTSSPTTTETT 2547

  Fly  2337 YKVMFSKKK-------PTWNTVLSTDGQARIFEANHDAETER----RHHFKNPIL---------- 2380
            .::..:..|       ||..:|.||..:..........|||.    ..|...||:
 Frog  2548 TEITTTTSKTTSATPGPTTTSVSSTTTETLTTTECTTEETEGPSSIATHTTTPIITTQSTTSPPV 2612

  Fly  2381 -------------TQYIKI----VPAYW---------------------EKNINMR--------- 2398
                         ||.:|.    ||...                     |...|.:
 Frog  2613 IIHTFSTTIGTPPTQQVKSTTSPVPTTTSGTETFTSTTTTPTTTETTTKETTTNPKTTSSTPGPT 2677

  Fly  2399 --------IE-------------------------------------PLGCFLPYP--------- 2409
                    ||                                     |.|...|.|
 Frog  2678 TTSVSPTTIETLTTTECTTEETEESPTTTHTTTPRLTTTPHTIPTSTPQGTTTPVPTTTSGTVTF 2742

  Fly  2410 -----------------------------------EIQRQVPVEESK-PTKCNICDGVSTSSSTT 2438
                                               ..:.....:|:: |:........|||.|||
 Frog  2743 TSTTTSPTTTETTTTSTSTATSTTPEPTTTIVSPTTTETLTTTKETEGPSSTTTHTTTSTSQSTT 2807

  Fly  2439 GCQCQDQLFWDGNTCVQHNL----------CPCI--------ENYVSY-PIGSKFE------NSA 2478
            ......   |...|......          .||:        |:|.|| |.|.::|      |:.
 Frog  2808 SVTITT---WPSTTTTTKETTSPTSTSTLSTPCVCWWTEWFDESYPSYEPSGGEYETYENIRNAG 2869

  Fly  2479 CEDCVCVLGGHKNCKPKKCPPCLGGKLRPVITSD------CFCK------------------CEP 2519
            .|  :|....:.:|:.:|.|.....:|...:|.|      |:.|                  |.|
 Frog  2870 KE--ICEKPENISCRAEKFPDTPLDQLGQKVTCDVSNGLTCYNKDQTGFLPVCYNYQISVYCCNP 2932

  Fly  2520 --C-------------------------------------------------------------- 2520
              |
 Frog  2933 PGCTSATTPTSTTTPTSTTSPTSTTTPTSTTTPTSTTTTTETPSTTTTTTTTITTVPTSTTLETT 2997

  Fly  2521 -----------------PKHQRLCP-------SSGDCIPEILWCNGVQDCADDEDASCS-----D 2556
                             |......|       :|....|..:.....|:.......:.|     .
 Frog  2998 TTPFSTTTSGTIYTESTPVSTTTAPTTILETSTSLTTTPSTIRTTTTQETTTSVPTTTSGTETFT 3062

  Fly  2557 SFTVEP---DVSREKNETEVITCPVPVCPPQMKIR------------ITEKKSRKMSKMFTFS-- 2604
            |.|..|   :.:.||..|.:.|...|..|....:.            .||:.......:.|||
 Frog  3063 STTTSPTTTETTTEKTTTTLTTTSTPSGPTTTSVSHTTTESLTTTECTTEETEETTPVIGTFSTT 3127

  Fly  2605 --------KQVSIVDDGTTI---------------------------TKTKFISSKEQILAMPNR 2634
                    :|||..:..||.                           |.|.:..|:......|..
 Frog  3128 PATPPTEPQQVSTTEGSTTASTTTSKTTTTSTRETTTSTRETTTISSTTTPYTPSETTTTISPTT 3192

  Fly  2635 ELDFQLEEQCDEFTCVPIPSKQVDKNETVTCTEPK----CPEKYDVELDMSASKVGDCLRY---- 2691
            ...:...|.... |..|..:.......|.|...|.    .|.:.......:.::......|
 Frog  3193 TTTYTPTETTTT-TISPTTTTYTPTETTTTTISPTTTTYTPTETTTTTTYTPTETTTTTTYTPTE 3256

  Fly  2692 ------------------SCVLRPNKDDVCEIS--------GKSFTTFDGTVFKYGPCSHILARD 2730
                              :....|.:.....||        .::.||...|...|.|........
 Frog  3257 TTTTISPTTTTYTPTETTTTTYTPTETTTTTISPTTTTYTPTETTTTTSPTTTTYTPTETTTTTS 3321

  Fly  2731 IHSSSWSISVHQQCSDETRKVCHKVITIQDTEAGNELILLPHLKLKFNGYE------------FT 2783
            ..:::.|.:.......||........|...|.:.....:.|.....:...|            :|
 Frog  3322 PTTTTISPTTTTYTPTETTTTTSPTTTTPYTPSETTTTISPTTTTTYTPTETSTTTSPTTTTPYT 3386

  Fly  2784 VQQLIN--SPICKASFVVSQPGKTLLAVSTKY--------------------------------- 2813
            ..:...  ||....::..::...|....:|.|
 Frog  3387 PSETTTTISPTTTTTYTPTETSTTTSPTTTTYTPTETTTTTISPTTTTYTPTETTTTTTTYTPTE 3451

  Fly  2814 ----------------------------------------------------------------- 2813
                                                                             
 Frog  3452 TTTTTTYTPTETTTTTTYTPTETTTTISPTTTTYTPTETTTTTYTPTETTTTTISPTTTTYTPTE 3516

  Fly  2814 ------------------------------------------------GFWVQLDDIGI------ 2824
                                                            ..:...|....
 Frog  3517 TTTTTSPTTTTYTPTETTTTTSPTTTTISPTTTTYTPTETTTTTSPTTTTYTPTDTTTTTTTTTY 3581

  Fly  2825 ------------------------------------------------------VKVGISS---- 2831
                                                                  ....|||
 Frog  3582 TPTETTTTISPTTTTTSPTTTTYTPTETTTTTSPTTTTYTPTETTTTTTYTPTETTTTISSTTTT 3646

  Fly  2832 -------------KFIRTVDGLCGYYNGNQKDDKRSPDGQIIPNTEKF----------------- 2866
                         ....|:......|...:.....||...|.|.|..:
 Frog  3647 YTPTETTTTTSPTTTTTTMSPTTTTYTPTETTTTASPTTTISPTTTTYTPTETTTTTSPTTTTTI 3711

  Fly  2867 --------------------------------GDSWYDKRIPKDQCGDLK--------------- 2884
                                            .........|.:....:.
 Frog  3712 SPTTTTYTPTETTTTTTSPTTTPYTPSETTTTASPTTTTYTPTETTTTISPTTTTTTISPTTTTY 3776

  Fly  2885 CPREMQAKALQ-------------LC---NIIHHP-----------TFARCHKAVNYK----QFL 2918
            .|.|....:.:             ||   :..:||           |:  |:|.:..|    |..
 Frog  3777 TPTETTTFSTESTTTPAISSSTPCLCLYSDTTYHPGEEITSGVANGTW--CYKVICSKECEVQIE 3839

  Fly  2919 NNYC------------------------------------------------LEAACNCMMANNG 2935
            :.:|                                                ...:...:.....
 Frog  3840 HWFCGSSTTEIPITTTELSTSTTSQPTTQETTTPTTTIVTTTSETISTSQSTTPKSTTVISTTTS 3904

  Fly  2936 DPAA---CKCNILESFVKKCLSVNPL--------VQLTTWR----AVAQCEINCPSPLVHTDCYK 2985
            .|::   ......:|..|...|..||        ....||.    .:|:|..|....::     :
 Frog  3905 PPSSTTKSSTTTTKSTTKSIASTTPLGCPFDPYREHNETWMLCNCTMARCLENNVVEII-----E 3964

  Fly  2986 RRCEPSCDNVHGDDCPVLPDACFPGCYCPEGTVRKGPNCVPIS-------ECKDCVCNSLGASKY 3043
            .:|||.                 |...|..|   :.|..||..       || ||||:..|...|
 Frog  3965 LKCEPP-----------------PMITCASG---RPPVAVPDEDLCCWHWEC-DCVCSGWGDPHY 4008

  Fly  3044 MTYDRKSFSFNGNCTYLLSRDVVLPGVHTFQVYVSMDDCKKLGQPTPVEGGSCAKSLHILNGDHV 3108
            :|:|...:|:.|||||:|..::. ..|..|.||:....|....:.      ||.:::.:.:....
 Frog  4009 LTFDGSYYSYQGNCTYVLVEEIE-KKVDNFGVYIDNYYCGAFDRV------SCPRNIIVRHETQE 4066

  Fly  3109 IHVQRVPQKPKSLQVLVDGFEVKKIPYKDSWISLRQVVGKELVLSLPESHVELTASFEDLIFSLG 3173
            |.:......|.|:||||:| ||..:|||...:.: ...|...|:.:||....:|  |..:.||:.
 Frog  4067 IQILAKTLAPLSIQVLVNG-EVVGVPYKKYGVKI-YTSGINYVVEIPELKANIT--FNGMAFSVK 4127

  Fly  3174 VPSIKYGSKMEGLCGDCNGNAGND-LQPNPAKKKAGVDVIQSWQADEPKLGLVEECLSEDVPKEH 3237
            :|...:|...:|.||.|..|..:| :..|.........:..:|...:|:   ..||:|:
 Frog  4128 LPYNLFGGNTQGQCGTCTNNRADDCMMRNHTTTSNCEAMADTWIVHDPR---KPECISK------ 4183

  Fly  3238 CIPLPP--------EKDPCLQFYNAELFGKCPLAVDPIAYVSACQQDICK-PGNTQQGVCVALAA 3293
              ||||        :..|..:...::.|..|...|:...:..||..|.|. |.:..:  |.:|..
 Frog  4184 --PLPPTTTPSPSCKPSPLCELMKSQAFKACHSIVNHEDFYQACIFDSCHVPHSNME--CTSLQH 4244

  Fly  3294 YAKECNQHGICTNWR-RPQLCPYECPSDMVYEPCGCA--KNCDTIKALSEFDAVSLKNEAVVHTV 3355
            ||..|...|||.:|| :...|...||::.||..|..|  :.|.|    :..:...:|.:
 Frog  4245 YALLCGDQGICVDWRSQAPACAISCPANKVYNACAPAVPQTCQT----TPEEQTQMKED------ 4299

  Fly  3356 KTDEMCLSSERFEGCFCPPGKV---MDGGQCVPEIACTKCDDGLHLPDEKWKKDKCTECQCDSKG 3417
                    ....||||||.|.:   .|...||....|...|:......|.::.| |.:|
 Frog  4300 --------KRLVEGCFCPHGTMPFSTDKDVCVASCGCVGPDNIPRKYGEIFQLD-CQDC------ 4349

  Fly  3418 KTTCVEKKCQVEENICAEGYRPETIVSVDECCPRYRCVPETKDPSKLCLAPLVPICGPGQFKKEK 3482
                          :|.||       .....|..:.|                         |..
 Frog  4350 --------------VCREG-------GSGIFCQAHTC-------------------------KHT 4368

  Fly  3483 KDVNGCSQYICECIPKDQCEIIELRELLPGEIIV---NVEEGCCPTQKIECKPETCPKAPVNCQE 3544
            |::..|.                    |.|.:.|   :..:.||......|....|..|..||..
 Frog  4369 KNIRTCD--------------------LEGFVAVIQPSATDKCCNDTICRCDTSRCSNASPNCSI 4413

  Fly  3545 RFYEVKTIKEPGMCCSKHSCVPPKDLCIVQYELDEATKFTKTVGDKWTHAKEVCKQETCSYGPDG 3609
            .:..|.:|.| |.||..:.|| ||.:|:  :...|....:..:.||       |:...|.....|
 Frog  4414 GYEMVGSIPE-GHCCPTYQCV-PKQVCV--HGNAEYRPGSPVLSDK-------CQTCVCGNSSTG 4467

  Fly  3610 NAQVVSTLEQCLTDCAPGFSY-QNLDKTKCCGKCVQTSCIFE-----QKLYEVNALWKSADNCTT 3668
             .::......|...|.|||:. |:::  .|||.|.||.|:..     |.|...:.|....:|||.
 Frog  4468 -LEIQCQRVPCNKQCPPGFTLRQSIN--DCCGVCEQTHCVLNYDGAYQLLNPGDTLPAQNNNCTV 4529

  Fly  3669 YSCLKKDGQFLVTTSREVCP-------DVGSCLSHLLYQDGCCKRCKSEPLVEDKSSCLPVSLAE 3726
            |||.|...||:.:.|...||       :.|:.   .|..:||||.|     ::....|
 Frog  4530 YSCTKIKNQFISSVSNISCPQFFEDDCEPGTI---QLLPNGCCKIC-----IQKTKEC------- 4579

  Fly  3727 SRTKEILKF-PVQGHGTCVNADPIQGFTDCEGACSSGSKYNTLTDMHEKFCTCCSIKSYHPISVK 3790
                :|.:| ....:..|::..||| .:.|||.|.:.|.|:.........||||........:|.
 Frog  4580 ----KIQQFYDYLSYNNCISLQPIQ-ISRCEGTCDTFSMYSASAGAISHKCTCCQEVLTSQKTVN 4639

  Fly  3791 MICDDGHTFTQKHEVPSNCGC--SPC--SEFSDSAIDVRMQQ 3828
            :.|.:|.....::.....|.|  :.|  ::..||.::||.::
 Frog  4640 LRCTNGAVIAHQYLDVEQCNCVNTNCGPAQSQDSELNVRSRR 4681

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hml	NP_524060.2	VWD	485..636	CDD:459671	35/156 (22%)
		C8	684..754	CDD:462584	21/69 (30%)
		TIL	758..811	CDD:410995	19/59 (32%)
		VWD	840..1015	CDD:214566	51/182 (28%)
		C8	1054..1121	CDD:214843	21/69 (30%)
		TIL	1131..1185	CDD:410995	21/59 (36%)
		TIL	1245..1298	CDD:460351	17/56 (30%)
		VWD	1327..1498	CDD:214566	54/174 (31%)
		C8	1535..1609	CDD:214843	35/73 (48%)
		TIL	1938..2005	CDD:473303	18/171 (11%)
		FA58C	2089..2223	CDD:238014	33/273 (12%)
		FA58C	<2299..2403	CDD:238014	30/220 (14%)
		VWD	2703..2858	CDD:459671	28/399 (7%)
		TIL	2974..3030	CDD:460351	9/62 (15%)
		VWD	3035..3198	CDD:459671	48/163 (29%)
		C8	3248..3313	CDD:462584	18/66 (27%)
		VWC	3397..3451	CDD:450195	8/53 (15%)
		GHB_like	<3755..3813	CDD:473907	15/59 (25%)
muc2	XP_031757181.1	VWD	33..178	CDD:214566	35/152 (23%)
		C8	224..292	CDD:462584	21/69 (30%)
		TIL	296..352	CDD:410995	19/59 (32%)
		VWD	392..549	CDD:459671	47/172 (27%)
		C8	585..655	CDD:214843	22/70 (31%)
		TIL	665..722	CDD:410995	21/59 (36%)
		VWD	851..1007	CDD:214566	53/172 (31%)
		C8	1046..1120	CDD:214843	35/73 (48%)
		Mucin2_WxxW	1314..1405	CDD:463846	12/90 (13%)
		Mucin2_WxxW	1600..1688	CDD:463846	21/95 (22%)
		Mucin2_WxxW	1770..1858	CDD:463846	21/130 (16%)
		Mucin2_WxxW	1946..2034	CDD:463846	20/99 (20%)
		Mucin2_WxxW	2146..2234	CDD:463846	16/89 (18%)
		Mucin2_WxxW	2841..2929	CDD:463846	18/89 (20%)
		VWD	3990..4157	CDD:214566	53/178 (30%)
		C8	4200..4262	CDD:462584	18/63 (29%)
		VWC	4438..4498	CDD:450195	16/71 (23%)
		CT	4587..4660	CDD:214482	18/73 (25%)