Protein Alignment CG8757 and CBR1

DIOPT Version :10

• Sequence 1: NP_648664.2
• Gene: CG8757 / 39528
• FlyBaseID: FBgn0036380
• Length: 252
• Species: Drosophila melanogaster
• Sequence 2: NP_001748.1
• Gene: CBR1 / 873
• HGNCID: 1548
• Length: 277
• Species: Homo sapiens
• Alignment Length: 241
• Identity: 62/241 - (25%)
• Similarity: 102/241 - (42%)
• Gaps: 61/241 - (25%)

  Fly     8 VAVVSGASAGIGAACTRAL--IGAGMIVV---GLARRHERVEKLRS-GLSLEQQSRLHAIKCDIT 66
            ||:|:|.:.|||.|..|.|  :.:|.:|:   .:.|....|::|:: |||    .|.|.:..|..
Human     7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLS----PRFHQLDIDDL 67

  Fly    67 QEDQVLKAFDWTCRQLGGVDVLVSNAGIIGTGELSERDDGP---AMRSTIETNIMGTVYCVRESF 128
            |..:.|:  |:..::.||:||||:||||    .....|..|   ....|::||..||.....|..
Human    68 QSIRALR--DFLRKEYGGLDVLVNNAGI----AFKVADPTPFHIQAEVTMKTNFFGTRDVCTELL 126

  Fly   129 RSMKRRGTEGHVVIVNSVAGYQ-VPNLGPQL---------------------------------- 158
            ..:|   .:|.||.|:|:...: :.:..|:|
Human   127 PLIK---PQGRVVNVSSIMSVRALKSCSPELQQKFRSETITEEELVGLMNKFVEDTKKGVHQKEG 188

  Fly   159 -PSLNIYPATKFALRAMNEIYRQEF--QRHKTAVRVSTVSPGIVDT 201
             || :.|..||..:..::.|:.::.  ||....:.::...||.|.|
Human   189 WPS-SAYGVTKIGVTVLSRIHARKLSEQRKGDKILLNACCPGWVRT 233

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8757	NP_648664.2	Rossmann-fold NAD(P)(+)-binding proteins	1..247	CDD:473865	62/241 (26%)
CBR1	NP_001748.1	carb_red_PTCR-like_SDR_c	6..277	CDD:187585	62/241 (26%)