Protein Alignment CG8757 and NRE1

DIOPT Version :10

• Sequence 1: NP_648664.2
• Gene: CG8757 / 39528
• FlyBaseID: FBgn0036380
• Length: 252
• Species: Drosophila melanogaster
• Sequence 2: NP_012301.3
• Gene: NRE1 / 854853
• SGDID: S000001474
• Length: 254
• Species: Saccharomyces cerevisiae
• Alignment Length: 264
• Identity: 70/264 - (26%)
• Similarity: 110/264 - (41%)
• Gaps: 51/264 - (19%)

  Fly     7 KVAVVSGASAGIGAACTRAL--IGAGMIVVGLARRHERVEKLRSGLSLEQQSRLHAIKCDITQED 69
            ||.:|:|.|.|||.:....|  :....:|.|:||....::||:.    :...|...:..||| ||
Yeast     3 KVILVTGVSRGIGKSIVDVLFSLDKDTVVYGVARSEAPLKKLKE----KYGDRFFYVVGDIT-ED 62

  Fly    70 QVLKAF-DWTCRQLGGVDVLVSNAGIIGTGELSERDDGPAMRSTIETNIMGTVYCVRESFRSMKR 133
            .|||.. :...:..|.:|.||:|||::...:.....|..|.:...:.|....|..|..:...:|:
Yeast    63 SVLKQLVNAAVKGHGKIDSLVANAGVLEPVQNVNEIDVNAWKKLYDINFFSIVSLVGIALPELKK 127

  Fly   134 RGTEGHVVIVNSVAGYQVPNLGPQLPSLNIYPATK-----FALRAMNEIYRQEFQRHKTAVRVST 193
              |.|:||.|:|.|      ......|...|.::|     ||:...||         :..|:...
Yeast   128 --TNGNVVFVSSDA------CNMYFSSWGAYGSSKAALNHFAMTLANE---------ERQVKAIA 175

  Fly   194 VSPGIVDT---VILPEQI--QGIIKQHMPMLRS--------DDVADAVLWAIGTPPNVQVHNITI 245
            |:||||||   |.:.|.:  ..:..:.:.|.|.        |....|.::|     .:.:|.|
Yeast   176 VAPGIVDTDMQVNIRENVGPSSMSAEQLKMFRGLKENNQLLDSSVPATVYA-----KLALHGI-- 233

  Fly   246 KPQG 249
             |.|
Yeast   234 -PDG 236

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8757	NP_648664.2	Rossmann-fold NAD(P)(+)-binding proteins	1..247	CDD:473865	68/260 (26%)
NRE1	NP_012301.3	SPR-like_SDR_c	4..246	CDD:187625	69/263 (26%)