DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG8757 and NRE1

DIOPT Version :9

Sequence 1:NP_648664.2 Gene:CG8757 / 39528 FlyBaseID:FBgn0036380 Length:252 Species:Drosophila melanogaster
Sequence 2:NP_012301.3 Gene:NRE1 / 854853 SGDID:S000001474 Length:254 Species:Saccharomyces cerevisiae


Alignment Length:264 Identity:70/264 - (26%)
Similarity:110/264 - (41%) Gaps:51/264 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly     7 KVAVVSGASAGIGAACTRAL--IGAGMIVVGLARRHERVEKLRSGLSLEQQSRLHAIKCDITQED 69
            ||.:|:|.|.|||.:....|  :....:|.|:||....::||:.    :...|...:..||| ||
Yeast     3 KVILVTGVSRGIGKSIVDVLFSLDKDTVVYGVARSEAPLKKLKE----KYGDRFFYVVGDIT-ED 62

  Fly    70 QVLKAF-DWTCRQLGGVDVLVSNAGIIGTGELSERDDGPAMRSTIETNIMGTVYCVRESFRSMKR 133
            .|||.. :...:..|.:|.||:|||::...:.....|..|.:...:.|....|..|..:...:|:
Yeast    63 SVLKQLVNAAVKGHGKIDSLVANAGVLEPVQNVNEIDVNAWKKLYDINFFSIVSLVGIALPELKK 127

  Fly   134 RGTEGHVVIVNSVAGYQVPNLGPQLPSLNIYPATK-----FALRAMNEIYRQEFQRHKTAVRVST 193
              |.|:||.|:|.|      ......|...|.::|     ||:...||         :..|:...
Yeast   128 --TNGNVVFVSSDA------CNMYFSSWGAYGSSKAALNHFAMTLANE---------ERQVKAIA 175

  Fly   194 VSPGIVDT---VILPEQI--QGIIKQHMPMLRS--------DDVADAVLWAIGTPPNVQVHNITI 245
            |:||||||   |.:.|.:  ..:..:.:.|.|.        |....|.::|     .:.:|.|  
Yeast   176 VAPGIVDTDMQVNIRENVGPSSMSAEQLKMFRGLKENNQLLDSSVPATVYA-----KLALHGI-- 233

  Fly   246 KPQG 249
             |.|
Yeast   234 -PDG 236

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8757NP_648664.2 YdfG 1..252 CDD:226674 70/264 (27%)
NADB_Rossmann 1..247 CDD:304358 68/260 (26%)
NRE1NP_012301.3 SPR-like_SDR_c 4..246 CDD:187625 69/263 (26%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C157341291
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.840

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