Protein Alignment CG8757 and CBR4

DIOPT Version :10

• Sequence 1: NP_648664.2
• Gene: CG8757 / 39528
• FlyBaseID: FBgn0036380
• Length: 252
• Species: Drosophila melanogaster
• Sequence 2: XP_006714454.1
• Gene: CBR4 / 84869
• HGNCID: 25891
• Length: 247
• Species: Homo sapiens
• Alignment Length: 246
• Identity: 68/246 - (27%)
• Similarity: 120/246 - (48%)
• Gaps: 33/246 - (13%)

  Fly     6 NKVAVVSGASAGIGAACTRALIGAGMIVVGLARRHERVEKLRSGLSLEQQSRLHAIKCDITQEDQ 70
            :||..|.|.|.|||.|..:.:...|..:..:||..|..:.....|..:..    |..||:.:|..
Human     2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHL----AFSCDVAKEHD 62

  Fly    71 VLKAFDWTCRQLGGVDVLVSNAGIIGTGEL--SERDDGPAMRSTIETNIMGTVYCVRESFRSM-K 132
            |...|:...:.||.|:.||:.|||...|.|  ::.:|   |.|.:.||::|::...:.:.|:| :
Human    63 VQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTED---MVSQLHTNLLGSMLTCKAAMRTMIQ 124

  Fly   133 RRGTEGHVVIV----------NSVAGYQVPNLGPQLPSLNIYPATKFALRAMNEIYRQEFQRHKT 187
            ::|  |.:|.|          .|:.|.: .|.|.     ::|.|:|..|...:....:|..|.|
Human   125 QQG--GSIVNVGHRREMLLHKRSIVGLK-GNSGQ-----SVYSASKGGLVGFSRALAKEVARKK- 180

  Fly   188 AVRVSTVSPGIVDTVILPEQIQGIIKQHMPMLR---SDDVADAVLWAIGTP 235
             :||:.|:||.|.|.:..:..:..:|:::|:.|   :.:||.||::.:.:|
Human   181 -IRVNVVAPGFVHTDMTKDLKEEHLKKNIPLGRFGETIEVAHAVVFLLESP 230

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8757	NP_648664.2	Rossmann-fold NAD(P)(+)-binding proteins	1..247	CDD:473865	68/246 (28%)
CBR4	XP_006714454.1	Rossmann-fold NAD(P)(+)-binding proteins	3..243	CDD:473865	68/245 (28%)