DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8757 and dhrs11b.1

DIOPT Version :9

Sequence 1:	NP_648664.2	Gene:	CG8757 / 39528	FlyBaseID:	FBgn0036380	Length:	252	Species:	Drosophila melanogaster
Sequence 2:	NP_001002143.2	Gene:	dhrs11b.1 / 791770	ZFINID:	ZDB-GENE-040625-155	Length:	255	Species:	Danio rerio

Alignment Length:	261	Identity:	97/261 - (37%)
Similarity:	154/261 - (59%)	Gaps:	25/261 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MERWCNKVAVVSGASAGIGAACTRALIGAGMIVVGLARRHERVEKLRSG-LSLEQQSRLHAIKCD 64
            |:||..:||:|:|||.|||||..:||:..||.|||.||..|::|||.:. :|......|...|||
Zfish     1 MDRWKGRVALVTGASVGIGAAIAKALVQHGMKVVGCARNVEQIEKLAAECVSGGYSGALFPYKCD 65

  Fly    65 ITQEDQVLKAFDWTCRQLGGVDVLVSNAGI-----IGTGELSERDDGPAMRSTIETNIMGTVYCV 124
            ::.||:||..|.|...|..||||.::|||:     :..|:.|      ..|:.:..|::|...|.
Zfish    66 LSVEDEVLSMFSWIKAQHKGVDVCINNAGLALPEPLLNGKAS------GWRTMMNVNVIGLSLCT 124

  Fly   125 RESFRSMKRRG-TEGHVVIVNSVAGYQVPNLGPQLPSLNIYPATKFALRAMNEIYRQEFQRHKTA 188
            ||:|:|||.|. .:||::.:||::|::|.|..    ..:.|.|||:|:.|:.|..|||.:..||.
Zfish   125 REAFQSMKERNIDDGHIININSMSGHRVVNSA----YTHFYTATKYAVTALTEGLRQELREAKTH 185

  Fly   189 VRVSTVSPGIVDTVIL-------PEQIQGIIKQHMPMLRSDDVADAVLWAIGTPPNVQVHNITIK 246
            :|.:::|||:|:|...       .::.....|. :..|:.||:|:||::.:..||:||:.:|.::
Zfish   186 IRATSISPGLVETEFAYRLFSENQDKASATYKS-IKCLQPDDLANAVVYVLSAPPHVQIGDIQMR 249

  Fly   247 P 247
            |
Zfish   250 P 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8757	NP_648664.2	YdfG	1..252	CDD:226674	97/261 (37%)
CG8757	NP_648664.2	NADB_Rossmann	1..247	CDD:304358	96/259 (37%)
dhrs11b.1	NP_001002143.2	YdfG	1..253	CDD:226674	97/261 (37%)
dhrs11b.1	NP_001002143.2	Mgc4172-like_SDR_c	1..250	CDD:187601	96/259 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576243
Domainoid	1	1.000	169	1.000	Domainoid score	I3763
eggNOG	1	0.900	-	-		E2759_KOG1205
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H133750
Inparanoid	1	1.050	200	1.000	Inparanoid score	I3745
OMA	1	1.010	-	-		QHG45743
OrthoDB	1	1.010	-	-		D1190834at2759
OrthoFinder	1	1.000	-	-		FOG0000588
OrthoInspector	1	1.000	-	-		mtm6354
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR43115
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X367
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.870