Protein Alignment CG8757 and DHRS11

DIOPT Version :9

• Sequence 1: NP_648664.2
• Gene: CG8757 / 39528
• FlyBaseID: FBgn0036380
• Length: 252
• Species: Drosophila melanogaster
• Sequence 2: NP_077284.2
• Gene: DHRS11 / 79154
• HGNCID: 28639
• Length: 260
• Species: Homo sapiens
• Alignment Length: 262
• Identity: 89/262 - (33%)
• Similarity: 149/262 - (56%)
• Gaps: 27/262 - (10%)

  Fly     1 MERWCNKVAVVSGASAGIGAACTRALIGAGMIVVGLARRHERVEKLRSGL-SLEQQSRLHAIKCD 64
            ||||.:::|:|:|||.|||||..|||:..|:.|||.||....:|:|.:.. |......|...:||
Human     6 MERWRDRLALVTGASGGIGAAVARALVQQGLKVVGCARTVGNIEELAAECKSAGYPGTLIPYRCD 70

  Fly    65 ITQEDQVLKAFDWTCRQLGGVDVLVSNAGI-----IGTGELSERDDGPAMRSTIETNIMGTVYCV 124
            ::.|:.:|..|.....|..|||:.::|||:     :.:|..|      ..:.....|::....|.
Human    71 LSNEEDILSMFSAIRSQHSGVDICINNAGLARPDTLLSGSTS------GWKDMFNVNVLALSICT 129

  Fly   125 RESFRSMKRRGT-EGHVVIVNSVAGYQV-PNLGPQLPSLNIYPATKFALRAMNEIYRQEFQRHKT 187
            ||:::|||.|.. :||::.:||::|::| |     |...:.|.|||:|:.|:.|..|||.:..:|
Human   130 REAYQSMKERNVDDGHIININSMSGHRVLP-----LSVTHFYSATKYAVTALTEGLRQELREAQT 189

  Fly   188 AVRVSTVSPGIVDTVIL-------PEQIQGIIKQHMPMLRSDDVADAVLWAIGTPPNVQVHNITI 245
            .:|.:.:|||:|:|...       ||:.....:| |..|:.:|||:||::.:.||.::|:.:|.:
Human   190 HIRATCISPGVVETQFAFKLHDKDPEKAAATYEQ-MKCLKPEDVAEAVIYVLSTPAHIQIGDIQM 253

  Fly   246 KP 247
            :|
Human   254 RP 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8757	NP_648664.2	YdfG	1..252	CDD:226674	89/262 (34%)
		NADB_Rossmann	1..247	CDD:304358	88/260 (34%)
DHRS11	NP_077284.2	Mgc4172-like_SDR_c	6..256	CDD:187601	89/262 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143375
Domainoid	1	1.000	154	1.000	Domainoid score	I4257
eggNOG	1	0.900	-	-		E2759_KOG1205
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	188	1.000	Inparanoid score	I3916
Isobase	1	0.950	-	0	Normalized mean entropy	S2090
OMA	1	1.010	-	-		QHG45743
OrthoDB	1	1.010	-	-		D1190834at2759
OrthoFinder	1	1.000	-	-		FOG0000588
OrthoInspector	1	1.000	-	-		otm40752
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR43115
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X367
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	13	12.860